Anticoccidial methods

ABSTRACT

The present invention is directed to anticoccidial methods, animal feed premixes, and animal feeds, employing a specified o-phenylenediamine or benzimidazole. The present invention is also directed to anticoccidial methods, animal feed premixes, and animal feeds employing two active agents. In such combined therapy, a first substance is a polyether antibiotic, and the second substance is a designated o-phenylenediamine, benzimidazole, or benzimidazoline.

BRIEF SUMMARY OF THE INVENTION

Coccidiosis is a protozoan disease of fowl and other animals. Uncontrolled, it is a devastating disease. Chemotherapeutics are known, such as the polyethers monensin and narasin, sold under the trademarks Coban® and Monteban®, respectively. However, there are various problems. Some chemotherapeutics cause undesirable side effects. Others, especially if used recurringly in a facility, lead to the development of reduced sensitivity or resistance to a particular chemotherapeutic or entire class of chemotherapeutics. For this reason, combinations are employed, such as the combination of narasin and nicarbazin, sold under the trademark Maxiban®. Also, "rotation" and "shuttle" regimens are used, in which different anticoccidial regimens are employed from one growout to the next, and during a growout. However, even with all of these available techniques, there is still a continuing need to discover new chemotherapeutic techniques for the control of coccidiosis.

It has now been discovered that certain phenylenediamines and benzimidazoles, more fully defined below, are efficacious against coccidiosis. These compounds can be employed to treat and/or prevent coccidiosis in fowl. They may be employed alone or, in a preferred embodiment, they are employed in combination with a polyether. In an especially preferred embodiment, the present combination therapy is used to prevent or treat coccidiosis attributable to a polyether-insensitive strain of Eimeria. The topic of drug insensitivity is well reviewed in

Jeffers, T. K. Coccidia and intestinal coccidiomorphs, Vth International Coccidiosis Conference, Tours (France) Oct. 17-20, 1989. Ed. INRA Publ., 1989 (Les Colloques de I'INRA, no. 49), pages 295-308. Anticoccidial drug resistance: a review with emphasis on the polyether ionophores.

DETAILED DESCRIPTION OF THE INVENTION

The present invention is directed to a method of preventing or treating coccidiosis in a fowl which comprises administering to the fowl an effective amount of an active agent selected from compounds of the formulae ##STR1##wherein R¹ represents bromo or chloro,

m represents an integer of 0 or 1 and n represents an integer of from 0 to 3, with the sum of m and n being an integer of from 1 to 3;

R² represents difluoroacetyl, chlorodifluoroacetyl, 2,2,3,3-tetrafluoropropionyl, or a perfluoroalkanoyl of from C₂ to C₄ ;

R³ represents H, trichloroacetyl, or an independently selected R²;

R⁴ represents H, OH, OCH₃, or a group hydrolyzable to a foregoingR⁴ moiety; and

R⁵ represents difluoromethyl, chlorodifluoromethyl, 1,1,2,2-tetrafluoroethyl, or a perfluoroalkyl of C₁ -C₃ ;

or a physiologically acceptable salt of a Formula II compound.

The present invention is also directed to animal feed premixes and final animal feeds comprising an active agent as defined above.

Further, the invention is directed to anticoccidial methods comprising administering both an active agent as defined above, or a benzimidazoline as defined below, as well as a polyether antibiotic. Animal feed premixes and final animal feeds comprising both (1) a phenylenediamine, benzimidazole, or benzimidazoline, and (2) a polyether, are another aspectof the present invention. This combined therapy has unexpectedly been foundto provide excellent control of coccidiosis attributable to polyether-insensitive strains.

The benzimidazoline compounds to be employed in this embodiment are of the formula ##STR2##wherein R¹, m, n, and R⁵ have the same meanings set forth above; and R⁶ represents sodium, potassium, lithium, silver, calcium, ammonium, or substituted ammonium derived from an organic amine which is as basic as, or more basic than, ammonia.

The compounds of Formula I, II, and III, are prepared in known procedures, and a large number of specific compounds are taught in the literature. Thefollowing U.S. patents

Formula I: U.S. Pat. Nos. 3,557,211, 3,907,892; 3,989,840;

Formula II: U.S. Pat. No. 3,980,784;

Formula III: U.S. Pat. No. 4,265,901;

teach the synthesis of many of the compounds to be employed in the present invention, and are hereby incorporated by reference. Several review articles exist and further illustrate the synthesis of compounds to be empolyed in the present invention:

Chem. Heterocycl. Compd. 40, #1 (1981), pages 1-285

J. Fluoro. Chem. 56, #1 (1992), pages 1-27

Prog. Drug Res. 27 (1983), pages 85-161

Chem. Rev. 74, #3 (1974), pages 279-314.

These also are hereby incorporated by reference.

Compounds of Formula I which can be employed in the present invention include the following:

    ______________________________________                                         Example #                                                                              Name                                                                   ______________________________________                                          1      3-nitro-5-(trifluoromethyl)-N.sup.1 -(difluoroacetyl)-o-                       phenylenediamine                                                        2      3-nitro-5-chloro-N.sup.1,N.sup.2 -bis(2,2,3,3-                                 tetrafluoropropionyl)-o-phenylenediamine                                3      3-nitro-5-chloro-N.sup.1 -(2,2,3,3-tetrafluoropropionyl)-o-                    phenylenediamine                                                        4      3-nitro-5-(trifluoromethyl)-N.sup.1,N.sup.2 -bis(2,2,3,3-                      tetrafluoropropionyl)-o-phenylenediamine                                5      3-nitro-5-(trifluoromethyl)-N.sup.1 -(2,2,3,3-                                 tetrafluoropropionyl)-o-phenylenediamine                                6      3-nitro-5-(trifluoromethyl)-N.sup.1 -(2-(trifluoromethyl)-                     2,3,3,3-tetrafluoropropionyl)-o-phenylenediamine                        7      3-nitro-5-(trifluoromethyl)-N.sup.1,N.sup.2 -bis(2-                            (trifluoromethyl)-2,3,3,3-                                                     tetrafluoropropionyl)-o-phenylenediamine                                8      5-nitro-3-(trifluoromethyl)-N.sup.1 -(perfluoropropionyl)-                     o-phenylenediamine                                                      9      3-nitro-5-(trifluoromethyl)-N.sup.1 -(perfluoro-n-butyryl)-                    o-phenylenediamine                                                     10      5-nitro-3-(trifluoromethyl)-N.sup.1 -(trifluoroacetyl)-o-                      phenylenediamine                                                       11      3-nitro-5-chloro-N.sup.1,N.sup.2 -bis(trifluoroacetyl)-                        o-phenylenediamine                                                     12      3-nitro-5-(trifluoromethyl)-N.sup.1, N.sup.2 -bis                              (trifluoroacetyl)-o-phenylenediamine                                   13      3-nitro-5-chloro-N.sup.1 -(trifluoroacetyl)-o-                                 phenylenediamine                                                       14      3-nitro-5-(trifluoromethyl)-N.sup.1 -(perfluoropropionyl)-                     o-phenylenediamine                                                     15      3-nitro-5-(trifluoromethyl)-N.sup.1 -(perfluoropropionyl)-                     N.sup.2 -(trifluoroacetyl)-o-phenylenediamine                          16      3-nitro-5-(trifluoromethyl)-N.sup.1 -(trifluoroacetyl)-o-                      phenylenediamine                                                       17      5-nitro-3-(trifluoromethyl)-N.sup.1 -(1,1,2,2-                                 tetrafluoropropionyl)-o-phenylenediamine                               18      6-nitro-4-(trifluoromethyl)-N.sup.1 -(trifluoroacetyl)-N.sup.2 -               (trichloroacetyl)-o-phenylenediamine                                   19      6-nitro-4-(trifluoromethyl)-N.sup.1 -(perfluoropropionyl)-                     N.sup.2 -(trichloroacetyl)-o-phenylenediamine                          20      3-nitro-5-(trifluoromethyl)-N.sup.  1 -(perfluoropropionyl)-                   N.sup.2 -(trichloroacetyl)-o-phenylenediamine                          ______________________________________                                    

Compounds of Formula II which can be employed in the present invention include the following:

    ______________________________________                                         Example #                                                                              Name                                                                   ______________________________________                                         21      5-nitro-2,6-bis(trifluoromethyl)benzimidazole                          22      4-nitro-6-(trifluoromethyl)-2-(perfluoroethyl)                                 benzimidazole                                                          23      4-nitro-2,6-bis(trifluoromethyl)benzimidazole                          24      6-nitro-5-chloro-2-(trifluoromethyl)benzimidazole                      25      4-nitro-6-chloro-2-(trifluoromethyl)benzimidazole                      26      4-nitro-6-(trifluoromethyl)-2-(difluoromethyl)                                 benzimidazole                                                          27      5-nitro-4-chloro-2-(trifluoromethyl)benzimidazole                      28      7-nitro-4-chloro-2-(trifluoromethyl)benzimidazole                      29      4-nitro-2,6-bis(trifluoromethyl)benzimidazole                                  sodium salt                                                            30      6-nitro-4-chloro-2-(trifluoromethyl)benzimidazole                      31      4-nitro-5-chloro-2-(trifluoromethyl)benzimidazole                      32      7-nitro-4,5-dichloro-2-(trifluoromethyl)benzimidazole                  33      4-nitro-5,6-dichloro-2-(trifluoromethyl)benzimidazole                  34      4-nitro-5,6-dichloro-2-(perfluoroethyl)benzimidazole                   35      4-nitro-7-bromo-2,6-bis(trifluoromethyl)                                       benzimidazole                                                          36      4-nitro-6-(trifluoromethyl)-2-                                                 (chlorodifluoromethyl)benzimidazole                                    37      4-nitro-2,6-bis(trifluoromethyl)-7-                                            chlorobenzimidazole                                                    38      6-nitro-2,4-bis(trifluoromethyl)benzimidazole                          39      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole                                         40      7-nitro-5-chloro-2-(perfluoro-n-propyl)benzimidazole                   41      7-nitro-5-(trifluoromethyl)-2-(1-(trifluoromethyl)-                            2,3,3,3-tetrafluoroethyl)benzimidazole                                 42      7-nitro-5-chloro-2-(2,2,3,3-tetrafluoroethyl)                                  benzimidazole                                                          43      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with tri-n-                               butylamine                                                             44      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with                                      tribenzylamine                                                         45      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with decylamine                   46      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with                                      phenethylamine                                                         47      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with                                      di-n-hexylamine                                                        48      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with                                      tri-n-propylamine                                                      49      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with                                      dodecylamine                                                           50      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with                                      triethylamine                                                          51      4-nitro-6-(trifluoromethyl)-2-(perfluoroethyl)                                 benzimidazole, sodium salt                                             52      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, tetra-n-                                       heptylammonium salt                                                    53      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, tetra-n-                                       butylammonium salt                                                     54      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, tetra-n-                                       propylammonium salt                                                    55      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole,                                                benzyltrimethylammonium salt                                           56      1-hydroxy-4-nitro-2,6-bis(trifluoromethyl)                                     benzimidazole                                                          57      1-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazole                                         58      1-hydroxy-4-nitro-6-(trifluoromethyl)-2-                                       (chlorodifluoromethyl)benzimidazole                                    59      allyl 4-nitro-2,6-bis(trifluoromethyl)-1-                                      benzimidazolecarboxylate                                               60      4-nitrophenyl 4-nitro-2,6-bis(trifluoromethyl)-1-                              benzimidazolecarboxylate                                               61      4-nitro-N,N-di(n-propyl)-2,6-bis(trifluoromethyl)thio-                         1-benzimidazolecarboxamide                                             62      7-nitro-N,N-di(n-propyl)-2,5-bis(trifluoromethyl)                              thio-1-benzimidazolecarboxamide                                        63      7-nitro-1-(piperidinothionocarbonyl)-2,5-                                      bis(trifluoromethyl)benzimidazole                                      64      4-nitro-1-(piperidinothionocarbonyl)-2,6-                                      bis(trifluoromethyl)benzimidazole                                      65      N-ethyl-4-nitro-2,6-bis(trifluoromethyl)                                       benzimidazole-1-thiocarboxanilide                                      66      N-ethyl-7-nitro-2,5-bis(trifluoromethyl)                                       benzimidazole-1-thiocarboxanilide                                      67      ethyl 4-nitro-2,6-bis(trifluoromethyl)-1-                                      benzimidazolecarboxylate                                               68      phenyl 4-nitro-2,6-bis(trifluoromethyl)-1-                                     benzimidazolecarboxylate                                               69      phenyl 7-nitro-2,5-bis(trifluoromethyl)-1-                                     benzimidazolecarboxylate                                               70      N,N-diethyl-4-nitro-2,6-bis(trifluoromethyl)thio-1-                            benzimidazolecarboxamide                                               71      1-acetyl-7-nitro-2,5-bis(trifluoromethyl)benzimidazole                 72      1-acetyl-4-nitro-2,6-bis(trifluoromethyl)benzimidazole                 73      1-hexanoyl-7-nitro-2,5-bis(trifluoromethyl)                                    benzimidazole                                                          74      1-hexanoyl-4-nitro-2,6-bis(trifluoromethyl)                                    benzimidazole                                                          75      2,6-bis(trifluoromethyl)-4-nitro-1-                                            (phenylsulfonyl)benzimidazole                                          76      1-(p-anisoyl)-4-nitro-2,6-bis(trifluoromethyl)                                 benzimidazole                                                          77      1-methoxy-4-nitro-2,6-bis(trifluoromethyl)                                     benzimidazole                                                          78      n-hexyl 4-nitro-2,6-bis(trifluoromethyl)-1-                                    benzimidazolecarboxylate                                               79      isopropyl 4-nitro-2,6-bis(trifluoromethyl)-1-                                  benzimidazolecarboxylate                                               80      1-benzoyl-4-nitro-2,6-bis(trifluoromethyl)                                     benzimidazole                                                          81      1-(4-chlorobenzoyl)-4-nitro-2,6-                                               bis(trifluoromethyl)benzimidazole                                      82      N,N-dimethyl-4-nitro-2,6-bis(trifluoromethyl)thio-1-                           benzimidazolecarboxamide                                               83      N,N-dimethyl-7-nitro-2,5-bis(trifluoromethyl)thio-1-                           benzimidazolecarboxamide                                               84      4-nitro-1-(4-nitrobenzoyl)2,6-bis(trifluoromethyl)                             benzimidazole                                                          85      benzyl 2,6-bis(trifluoromethyl)-4-nitro-1-                                     benzimidazolecarboxylate                                               86      benzyl 2,5-bis(trifluoromethyl)-7-nitro-1-                                     benzimidazolecarboxylate                                               87      methyl 4-nitro-2,6-bis(trifluoromethyl)-1-                                     benzimidazolecarboxylate                                               88      methyl 7-nitro-2,5-bis(trifluoromethyl)-1-                                     benzimidazolecarboxylate                                               89      n-butyl 4-nitro-2,6-bis(trifluoromethyl)benzimidazole-                         1-carboxylate                                                          90      isopropyl 2-(chlorodifluoromethyl)-4-nitro-6-                                  (trifluoromethyl)-1-benzimidazolecarboxylate                           91      4-nitro-2,6-bis(trifluoromethyl)-1-benzimidazolyl                              methylcarbamate                                                        92      phenyl 2-(chlorodifluoromethyl)-4-nitro-6-                                     (trifluoromethyl)-1-benzimidazolecarboxylate                           93      benzyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-                                 trifluoromethyl)-1-benzimidazolecarboxylate                            94      1-methoxy-4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-                              (trifluoromethyl)benzimidazole                                         95      2-ethylhexyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-                           (trifluoromethyl)-1-benzimidazolecarboxylate                           96      octyl 7-nitro-2-(1,1,2,2-tetrafluoroethyl)-5-                                  (trifluoromethyl)-1-benzimidazolecarboxylate                           97      octyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-                                  (trifluoromethyl)-1-benzimidazolecarboxylate                           98      ethyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-                                  (trifluoromethyl)-1-benzimidazolecarboxylate                           99      isopropyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-                              (trifluoromethyl)-1-benzimidazolecarboxylate                           100     1-(phenoxycarbonyloxy)-2-(chlorodifluoromethyl)-4-                             nitro-6-(trifluoromethyl)benzimidazole                                 101     1-methoxy-2-(chlorodifluoromethyl)-4-nitro-6-                                  (trifluoromethyl)benzimidazole                                         102     ethyl 2-(chlorodifluoromethyl)-4-nitro-6-                                      (trifluoromethyl)-1-benzimidazolecarboxylate                           103     N,N-dimethyl-2-(chlorodifluoromethyl)-7-nitro-5-                               (trifluoromethyl)-thio-1-benzimidazolecarboxamide                      104     N,N-dimethyl-2-(chlorodifluoromethyl)-4-nitro-6-                               (trifluoromethyl)-thio-1-benzimidazolecarboxamide                      105     methyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-                                 (trifluoromethyl)-1-benzimidazolecarboxylate                           106     allyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-                                  (trifluoromethyl)-1-benzimidazolecarboxylate                           107     allyl 2-(chlorodifluoromethyl)-4-nitro-6-                                      (trifluoromethyl)-1-benzimidazolecarboxylate                           108     1-(phenylsulfonyl)-2-(1,1,2,2-tetrafluoroethyl)-4-nitro-                       6-(trifluoromethyl)benzimidazole                                       ______________________________________                                    

Compounds of Formula III which can be employed in the present invention include the following:

    ______________________________________                                         Example #                                                                              Name                                                                   ______________________________________                                         109     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, sodium salt                          110     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, tetra-n-                                     butylammonium salt                                                     111     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline,                                              tetraethylammonium salt                                                112     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, silver salt                          113     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, sodium salt                          114     2-hydroxy-4-nitro-2,6-bis(trifluoromethyl)                                     benzimidazoline, sodium salt                                           115     2-hydroxy-4-nitro-2,6-bis(trifluoromethyl)                                     benzimidazoline, triethylamine salt                                    116     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, lithium salt                         117     2-hydroxy-4-nitro-6-chloro-2-(difluoromethyl)                                  benzimidazoline, hemicalcium salt                                      118     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, hemicalcium salt                     ______________________________________                                    

The polyethers are a known class of antibiotics showing common structural features. A review article is found in the Kirk-Othmer Encyclopedia of Chemical Technology-4th Ed., Volume #3, pages 306-322, and this article isincorporated herein by reference. As noted in this review article, the polyethers exhibit anticoccidial activity, and are presently the principalchemotherapeutics, worldwide, for the control of coccidiosis.

Representative polyethers which can be used in the present invention include the following; the noted reference patents are incorportated herein by reference.

    ______________________________________                                         monensin              3,501,568                                                laidlomycin                                                                    nigericin                                                                      grisorixin                                                                     dianemycin                                                                     lenoremycin                                                                    salinomycin           3,857,948                                                narasin               4,038,384                                                lonomycin                                                                      antibiotic X206                                                                allorixin                                                                      septamycin                                                                     antibiotic A204       3,705,238                                                etheromycin                                                                    lasalocid             3,719,753                                                isolasalocid                                                                   lysocellin                                                                     antibiotic A23187     4,582,822                                                portmicin (anitbiotic A80190)                                                                        4,683,204                                                kijimicin                                                                      antibiotic A82810     EPO X-7412                                               maduramicin factor A (X-4868A)                                                                       4,407,946                                                maduramicin factor C (LLC-23024B)                                              semduramicin.                                                                  ______________________________________                                    

There are certain preferred embodiments of the present invention. A preferred embodiment of Formula I and II are compounds wherein the benzo ring is substituted by nitro and a single CF₃ (i.e., compounds wherein m=1 and n=0). In Formula I, the preference is for R² =trifluoroacetyl or (1,1,2,2-tetrafluoropropionyl) and R⁴ =H or the same moiety represented by R². In Formula II, the preference is for R⁵ =(1,1,2,2-tetrafluoroethyl). Especially preferred compounds are:

3-nitro-5-(trifluoromethyl)-N¹ -(2,2,3,3-tetrafluoropropionyl)-o-phenylenediamine

4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-tetrafluoroethyl)benzimidazole

1-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-tetrafluoroethyl)benzimidazole

Among the benzimidazolines of Formula III, preferences are the same for thebenzo substitution and R⁵ ; a preferred salt is sodium (R⁶). Thus, especially preferred compounds are

2-hydroxy-4-nitro-2,6-bis(trifluoromethyl)benzimidazoline, sodium salt

2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-tetrafluoroethyl)benzimidazoline, sodium salt

Among the polyethers, preferred compounds are

antibiotic A204,

portmicin,

antibiotic A82810,

maduramicin, and

semduramicin.

Combined therapy with both (1) a phenylenediamine, benzimidazole, or benzimidazoline, and (2) a polyether, is a preferred embodiment of the present invention.

The present invention can be employed for the control of coccidiosis in anyfowl. Chickens and turkeys are the species most commonly treated for coccidiosis but the present invention can also be used with other poultry species, such as ducks, geese, quail, pheasants and ostriches.

The present invention can be used to prevent or treat coccidiosis attributable to any species. The species which commonly cause coccidiosis in chickens are

Eimeria acervulina

Eimeria brunetti

Eimeria maxima

Eimeria necatrix

Eimeria tenella.

The species which commonly cause coccidiosis in turkeys are

Eimeria meleagrimitis

Eimeria gallopavonis

Eimeria adenoeides

Eimeria dispersa.

Coccidiosis in other poultry species is attributable to yet other protozoanspecies known to those skilled in the art.

The present invention is useful generally for the prevention and/or treatment of coccidiosis; however, it is particularly useful regarding those coccidiosis-causing species which are insensitive to the polyethers,or which, based on laboratory trials or intensive use experience, could become insensitive. Thus, the present invention presents a technique for controlling coccidiosis while reducing the risk of developing insensitivity or resistance to the polyethers.

The present invention is practiced in the usual fashion of anticoccidials, that is, because coccidiosis is a malady of the intestinal tract, an anticoccidial must be administered in a way to reach the intestinal tract.This is typically achieved by incorporating the present agents in the feed.Anticoccidials are sometimes administered via the drinking water, and this route is possible for the compounds of Formula I, II, and III, especially in their salt forms. However, because of their low solubility, the polyethers are not readily administered by this route. In the embodiment of the present invention which employs both a compound of Formula I, II, or III, as well as a polyether, the former can be administered by the feedand the lattervia the drinking water. In the most preferred practice however, both are administered in the feed.

The present active agents are incorporated into an animal feed in the manner usual for anticoccidials. Typically, a compound of Formula I or II,or a compound of Formula I, II, and III as well as a polyether, are incorporated into a "premix." The premix contains the active agent or agents as well as physiologically acceptable carriers and feedstuffs. The premix is relatively concentrated and is adapted to be diluted with other carriers, vitamin and mineral supplements, and feedstuffs to form the final animal feed. Premixes which are intermediate in concentration of active agent between a first premix and the final animal feed are sometimes employed in the industry and can be used in implementing the present invention.

When employing a compound of Formula I or II as sole active agent, a premixdesirably contains the agent at a concentration of from 0.1 to 50.0% by weight. Preferred premixes will generally contain a compound of Formula I or II at a concentration of from 0.5 to 25.0%, by weight. When empolying both a compound of Formula I, II, or III, as well as a polyether, a premixdesirably contains concentrations of from 0.2 to 25.0% by weight of each active agent. Combined therapy can also be obtained using one premix containing the compound of Formula I, II, or III, and a second premix containing the polyether. Both mixes are added to carriers, vitamin and mineral supplements, and feedstuffs to yield a single animal feed containing both active agents. The identity of the other components of thepremix and ultimate animal feed is not critical; exemplary formulations arelisted below.

Various compounds to be employed in accordance with the present invention were evaluated in a standardized chicken battery test. In this test, the respective compound was mixed well with a small portion of a basal diet, to constitute a premix, and the resulting premix was added to a large amount of the same basal diet. This resulted in the ultimate diet fed to the chickens, containing the respective compound.

The battery test was conducted with Peterson x Hubbard cockerel chicks, beginning when the chicks were approximately nine days old. There were generally four chicks per pen and three or four pens per treatment. All chicks were housed in stainless steel wire cages, 13"×21"×9". The respective diet and water were provided ad libitum beginning at approximately day nine. All birds except those of a non-infected control group were infected with two or three species of Eimeria; infection was bycrop intubation of sporulated oocysts, usually two days after the trial began (in some tests, one day after the trial began). The chicks were maintained on the trial for approximately nine days at which time they were killed and the intestinal tracts evaluated for the degree of lesions attributable to coccidiosis. Other parameters evaluated during the test were mortality, weight gain, and feed/gain.

The composition of the basal feed was as follows¹ :

    ______________________________________                                         Ingredients            %                                                       ______________________________________                                         Corn, Yellow Ground    53.42                                                   Soybean Meal (49%)     31.73                                                   Animal Fat             2.83                                                    Fish Meal-Menhaden     5.00                                                    Corn Distillers Dried Solubles                                                                        4.00                                                    Dicalcium Phosphate    1.28                                                    Ground Limestone       0.62                                                    Vitamin Premix TK-01 (1.03).sup.2                                                                     0.50                                                    Salt (NaCl)            0.30                                                    Trace Mineral Premix TK-01 (1.02).sup.3                                                               0.10                                                    Methionine Hydroxy Analog                                                                             0.17                                                    Selenium Premix.sup.3  0.05                                                    Total                  100.00                                                  ______________________________________                                          .sup.1 Final feed is in mash form.                                             .sup.2 Vitamin premix provides 3000 IU of Vitamin A, 900 ICU of Vitamin        D.sub.3, 40 mg of Vitamin E, 0.7 mg of Vitamin K, 1000 mg of choline, 70       mg of niacin, 4 mg of pantothenic acid, 4 mg of ribovlavin, 0.10 mg of         Vitamin B.sub.12, 0.10 mg of biotin and 125 mg of ethoxyquin per kg of         complete feed.                                                                 .sup.3 Trace mineral premixes provide 75 mg of Mn, 50 mg of Zn, 25 mg of       Fe, 1 mg of l, and 0.10 mg of Se per kg of complete feed.                

    ______________________________________                                         CALCULATED ANALYSIS                                                            ______________________________________                                         Crude Protein,   %        23.50                                                ME,              Kcal/kg  3100.00                                              ME/CP Ratio               132.00                                               Fat,             %        5.70                                                 Fiber,           %        2.70                                                 Ash,             %        6.00                                                 Calcium,         %        0.85                                                 Total P,         %        0.77                                                 Vitamin. A,      IU/kg    4765.00                                              Vitamin D.sub.3, ICU/kg   900.00                                               Vitamin E,       mg/kg    56.50                                                Xanthophyll,     mg/kg    8.30                                                 Manganese,       mg/kg    101.30                                               Copper,          mg/kg    17.20                                                Selenium         mcg/kg   251.00                                               Potassium,       mg/kg    9072.00                                              Iodine,          mg/kg    1.00                                                 Lysine,          %        1.41                                                 Methionine,      %        0.56                                                 TSAA,            %        0.920                                                Vitamin K,       mg/kg    0.70                                                 Choline,         mg/kg    2178.00                                              Niacin,          mg/kg    96.50                                                Pant. Acid,      mg/kg    12.60                                                Riboflavin,      mg/kg    6.40                                                 Thiamine,        mg/kg    2.80                                                 Folic Acid,      mg/kg    1.50                                                 Biotin,          mcg/kg   296.00                                               Vit. B.sub.12,   mcg/kg   107.00                                               Vitamin B.sub.6, mg/kg    7.60                                                 Linoleic Acid,   %        1.30                                                 Iron,            mg/kg    119.90                                               Zinc,            mg/kg    85.40                                                Magnesium,       mg/kg    2003.00                                              Sodium,          mg/kg    1670.00                                              Arginine,        %        1.685                                                Glycine,         %        1.400                                                Cystine,         %        0.356                                                Tryptophan,      %        0.333                                                ______________________________________                                    

Results of trials in accordance with the present invention are reported in the following tables. "#" columns refer to thenumber of pens. Mortality isreported using both (1) due to all causes, and (2) due to coccidiosis, only. Weight gain is calculated only for surviving chicks. In most experiments, feed:gain ratio was calculated using only pens in which no mortality occurred. However, in some experiments, an adjusted feed:gain ratio was calculated by correcting for mortality. To determine what methodwas used to calculate feed:gain, compare the number of pens used to calculate mortality with the number of pens used to calculate feed:gain. If no mortality occurred within a particular treatment group, then all pens were used to calculate feed:gain ratio and no adjustment was necessary. If mortality occurred in a particular treatment group and thereare fewer pens used for feed:gain than for mortality, then feed:gain was calculated using only pens in which mortality did not occur. However, if mortality occurred and the number of pens used to calculate mortality is equal to the number of pens used to calculate feed:gain, then an adjusted feed:gain ratio was calculated. Statistical analyses were by the Student-Newman-Keul's Multiple Range Test, using Gerbhardt's Algorithm forunequal sample size. Means within a column with no common superscript letter differ (P<0.05).

    __________________________________________________________________________     EXPERIMENT NO. 1                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                     Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 0.0 b                                                                               3 0.0 a                                                                               3 272.3 a                                                                             3 1.584 b-c                                                                           3 0.00 d                                                                              3 0.00 e                              IC                                                                             0     3 8.3 b                                                                               3 8.3 a                                                                               3 221.6 a-b                                                                           2 1.737 a-c                                                                           3 6.00 a                                                                              3 3.33 a                              A82810                                                                         2     3 0.0 b                                                                               3 0.0 a                                                                               3 202.7 b                                                                             3 1.908 a                                                                             3 6.08 a                                                                              3 3.33 a                              4     3 0.0 b                                                                               3 0.0 a                                                                               3 221.4 a-b                                                                           3 1.817 a-c                                                                           3 3.83 a-c                                                                            3 3.08 a-b                            8     3 0.0 b                                                                               3 0.0 a                                                                               3 231.8 a-b                                                                           3 1.718 a-c                                                                           3 1.50 c-d                                                                            3 2.92 a-c                            Example No. 57                                                                 3     3 8.3 b                                                                               3 8.3 a                                                                               3 217.1 a-b                                                                           2 1.879 a-b                                                                           3 5.33 a-b                                                                            3 3.42 a                              6     3 8.3 b                                                                               3 8.3 a                                                                               3 221.8 a-b                                                                           2 1.715 a-c                                                                           3 2.75 b-d                                                                            3 2.92 a-c                            12    3 16.7 b                                                                              3 0.0 a                                                                               3 235.6 a-b                                                                           2 1.706 a-c                                                                           3 0.00 d                                                                              3 0.33 e                              A82810 + Example No. 57                                                        2 + 3 3 16.7 b                                                                              3 16.7 a                                                                              3 193.1 b                                                                             2 1.926 a                                                                             3 4.08 a-c                                                                            3 3.33 a                              2 + 6 3 8.3 b                                                                               3 0.0 a                                                                               3 239.8 a-b                                                                           2 1.769 a-c                                                                           3 0.58 d                                                                              3 2.56 a-d                            2 + 12                                                                               3 16.7 b                                                                              3 0.0 a                                                                               3 224.6 a-b                                                                           1 1.843 a- c                                                                          3 0.00 d                                                                              3 0.83 e                              4 + 3 3 0.0 b                                                                               3 0.0 a                                                                               3 255.4 a-b                                                                           3 1.675 a-c                                                                           3 1.00 c-d                                                                            3 2.58 a-d                            4 + 6 3 8.3 b                                                                               3 0.0 a                                                                               3 248.7 a-b                                                                           2 1.692 a-c                                                                           3 0.00 d                                                                              3 1.56 b-e                            4 + 12                                                                               3 75.0 a                                                                              3 0.0 a                                                                               3 220.9 a-b   3 1.50 c-d                                                                            3 1.17 d-e                            8 + 3 3 0.0 b                                                                               3 0.0 a                                                                               3 269.8 a                                                                             3 1.546 c                                                                             3 0.58 d                                                                              3 1.33 c-e                            8 + 6 3 8.3 b                                                                               3 0.0 a                                                                               3 257.4 a-b                                                                           2 1.710 a-c                                                                           3 0.25 d                                                                              3 0.92 e                              8 + 12                                                                               3 41.7 b                                                                              3 0.0 a                                                                               3 238.6 a-b                                                                           1 1.758 a-c                                                                           3 0.00 d                                                                              3 0.33 e                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 2                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                         Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 8.3 a                                                                               3 0.0 a                                                                               3 276.8 a                                                                             2 1.537 b                                                                             3 0.00 d                                                                              3 0.00 c                              IC                                                                             0     3 25.0 a                                                                              3 16.7 a                                                                              3 174.1 d-e   3 7.50 a-b                                                                            3 3.44 a                              A82810                                                                         2     3 8.3 a                                                                               3 8.3 a                                                                               3 154.6 e                                                                             2 2.332 a                                                                             3 8.75 a                                                                              3 3.42 a                              4     3 0.0 a                                                                               3 0.0 a                                                                               3 172.2 d-e                                                                           3 2.053 a-b                                                                           3 7.83 a- b                                                                           3 3.08 a                              8     3 0.0 a                                                                               3 0.0 a                                                                               3 230.0 a-d                                                                           3 1.667 b                                                                             3 8.00 a-b                                                                            3 3.08 a                              Example No. 57                                                                 3     3 0.0 a                                                                               3 0.0 a                                                                               3 180.0 d-e                                                                           3 2.065 a-b                                                                           3 8.75 a                                                                              3 3.50 a                              6     3 8.3 a                                                                               3 8.3 a                                                                               3 184.6 c-e                                                                           2 2.079 a-b                                                                           3 8.42 a                                                                              3 3.58 a                              12    3 41.7 a                                                                              3 0.0 a                                                                               3 235.8 a-d                                                                           1 1.725 a-b                                                                           3 3.00 c-d                                                                            3 1.25 b-c                            A82810 + Example No. 57                                                        2 + 3 3 0.0 a                                                                               3 0.0 a                                                                               3 201.2 b-e                                                                           3 1.870 a-b                                                                           3 7.00 a-b                                                                            3 3.33 a                              2 + 6 3 8.3 a                                                                               3 0.0 a                                                                               3 249.8 a-c                                                                           2 1.626 b                                                                             3 1.00 d                                                                              3 1.03 b-c                            2 + 12                                                                               3 16.7 a                                                                              3 0.0 a                                                                               3 215.7 a-e                                                                           1 1.881 a-b                                                                           3 0.00 d                                                                              3 0.33 c                              4 + 3 3 25.0 a                                                                              3 0.0 a                                                                               3 229.0 a-d                                                                           1 1.698 a-b                                                                           3 7.78 a-b                                                                            3 3.06 a                              4 + 6 3 0.0 a                                                                               3 0.0 a                                                                               3 245.8 a-c                                                                           3 1.693 b                                                                             3 1.58 d                                                                              3 2.08 a-b                            4 + 12                                                                               3 41.7 a                                                                              3 0.0 a                                                                               2 211.3 a-e                                                                           1 1.808 a-b                                                                           2 0.00 d                                                                              2 0.00 c                              8 + 3 3 8.3 a                                                                               3 0.0 a                                                                               3 258.3 a-b                                                                           2 1.608 b                                                                             3 4.83 b-c                                                                            3 2.06 a-b                            8 + 6 3 8.3 a                                                                               3 0.0 a                                                                               3 255.5 a-b                                                                           2 1.513 b                                                                             3 1.00 d                                                                              3 0.05 c                              8 + 12                                                                               3 25.0 a                                                                              3 0.0 a                                                                               3 215.2 a-e                                                                           1 1.813 a-b                                                                           3 0.00 d                                                                              3 0.00 c                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 3                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                     Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 0.0 b                                                                               3 0.0 b                                                                               3 274.8 a                                                                             3 1.549 b                                                                             3 0.00 d                                                                              3 0.00 d                              IC                                                                             0     3 16.7 b                                                                              3 16.7 a                                                                              3 195.2 b                                                                             1 2.305 a-b                                                                           3 5.25 a                                                                              3 3.67 a                              A82810                                                                         2     3 0.0 b                                                                               3 0.0 b                                                                               3 228.6 a-b                                                                           3 1.886 a-b                                                                           3 2.00 b                                                                              3 2.67 b                              4     3 0.0 b                                                                               3 0.0 b                                                                               3 255.2 a                                                                             3 1.762 b                                                                             3 1.25 c                                                                              3 3.42 a-b                            8     3 0.0 b                                                                               3 0.0 b                                                                               3 244.2 a                                                                             3 1.772 b                                                                             3 1.17 c                                                                              3 3.33 a-b                            Example No. 113                                                                6     3 0.0 b                                                                               3 0.0 b                                                                               3 244.7 a                                                                             3 1.747 b                                                                             3 0.58 d                                                                              3 1.50 c                              12    3 0.0 b                                                                               3 0.0 b                                                                               3 182.1 b                                                                             3 2.105 a-b                                                                           3 0.00 d                                                                              3 0.17 d                              A82810 + Example No. 113                                                       2 + 6 3 0.0 b                                                                               3 0.0 b                                                                               3 254.5 a                                                                             3 1.722 b                                                                             3 0.00 d                                                                              3 0.58 d                              2 + 12                                                                               3 8.3 b                                                                               3 0.0 b                                                                               3 192.3 b                                                                             2 2.125 a-b                                                                           3 0.00 d                                                                              3 0.00 d                              4 + 6 3 0.0 b                                                                               3 0.0 b                                                                               3 251.8 a                                                                             3 1.731 b                                                                             3 0.00 d                                                                              3 0.75 d                              4 + 12                                                                               3 16.7 b                                                                              3 0.0 b                                                                               3 193.9 b                                                                             1 2.006 a-b                                                                           3 0.00 d                                                                              3 0.19 d                              8 + 6 3 8.3 b                                                                               3 0.0 b                                                                               3 254.0 a                                                                             2 1.839 a-b                                                                           3 0.00 d                                                                              3 0.39 d                              8 + 12                                                                               3 0.0 b                                                                               3 0.0 b                                                                               3 185.7 b                                                                             3 2.323 a                                                                             3 0.00 d                                                                              3 0.00 d                              8 + 24                                                                               1 75.0 a                                                                              1 0.0 b                                                                               1 67.0 c      1 0.00 d 0.00 d                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 4                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                         Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 0.0 c                                                                               3 0.0 b                                                                               3 295.8 a                                                                             3 1.578 d                                                                             3 0.00 c                                                                              3 0.00 c                              IC                                                                             0     3 33.3 b-c                                                                            3 33.3 a                                                                              3 170.3 b-d   3 5.33 b                                                                              3 3.75 a                              A82810                                                                         2     3 41.7 b                                                                              3 41.7 a                                                                              3 138.4 d     3 6.42 b                                                                              3 3.75 a                              4     3 25.0 b-c                                                                            3 16.7 b                                                                              3 160.0 c-d                                                                           1 2.368 a                                                                             3 7.17 a-b                                                                            3 3.56 a                              8     3 0.0 c                                                                               3 0.0 b                                                                               3 208.3 b-d                                                                           3 1.978 a-c                                                                           3 8.67 a                                                                              3 3.58 a                              Example No. 113                                                                6     3 0.0 c                                                                               3 0.0 b                                                                               3 242.4 a-c                                                                           3 1.681 c-d                                                                           3 2.42 c                                                                              3 1.08 b                              12    3 16.7 b-c                                                                            3 0.0 b                                                                               3 180.4 b-d                                                                           2 2.130 a-b                                                                           3 0.00 c                                                                              3 0.00 c                              A82810 + Example No. 113                                                       2 + 6 3 0.0 c                                                                               3 0.0 b                                                                               3 251.0 a-b                                                                           3 1.771 b-d                                                                           3 0.17 c                                                                              3 0.83 b-c                            2 + 12                                                                               3 0.0 c                                                                               3 0.0 b                                                                               3 198.3 b-d                                                                           3 2.011 a-c                                                                           3 0.00 c                                                                              3 0.00 c                              4 + 6 3 0.0 c                                                                               3 0.0 b                                                                               3 241.7 a-c                                                                           3 1.783 b-d                                                                           3 0.00 c                                                                              3 0.25 c                              4 + 12                                                                               3 0.0 c                                                                               3 0.0 b                                                                               3 190.3 b-d                                                                           3 2.149 a-b                                                                           3 0.00 c                                                                              3 0.00 c                              4 + 24                                                                               2 75.0 a                                                                              2 0.0 b                                                                               2 72.8 e      2 0.00 e                                                                              2 0.00 c                              8 + 6 3 0.0 c                                                                               3 0.0 b                                                                               3 242.3 a-c                                                                           3 1.782 b-d                                                                           3 0.008 c                                                                             3 0.25 c                              8 + 12                                                                               3 8.3 c                                                                               3 0.0 b                                                                               3 163.0 c-d                                                                           2 2.235 a                                                                             3 0.00 c                                                                              3 0.00 c                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 5                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                     Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 252.6 a                                                                             3 1.677 a                                                                             3 0.00 c                                                                              3 0.00 e                              IC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 205.6 a                                                                             3 2.059 a                                                                             3 5.67 a                                                                              3 2.92 a-b                            A82810                                                                         2     3 0.0 a                                                                               3 0.0 a                                                                               3 226.1 a                                                                             3 1.894 a                                                                             3 4.83 a                                                                              3 2.92 a-b                            4     3 8.3 a                                                                               3 0.0 a                                                                               3 254.1 a                                                                             2 1.612 a                                                                             3 1.42 b-c                                                                            3 3.11 a-b                            8     3 0.0 a                                                                               3 0.0 a                                                                               3 252.5 a                                                                             3 1.802 a                                                                             3 0.92 b-c                                                                            3 1.83 a-d                            Example No. 57                                                                 2     3 16.7 a                                                                              3 0.0 a                                                                               3 212.4 a                                                                             1 1.878 a                                                                             3 5.00 a                                                                              3 3.44 a                              4     3 16.7 a                                                                              3 0.0 a                                                                               3 208.2 a                                                                             1 2.025 a                                                                             3 4.06 a                                                                              3 3.06 a-b                            8     3 16.7 a                                                                              3 8.3 a                                                                               3 233.7 a                                                                             1 1.829 a                                                                             3 1.28 b-c                                                                            3 3.39 a-b                            A82810 + Example No. 57                                                        2 + 2 3 8.3 a                                                                               3 8.3 a                                                                               3 225.5 a                                                                             2 1.862 a                                                                             3 3.17 a-b                                                                            3 2.58 a-c                            2 + 4 3 8.3 a                                                                               3 0.0 a                                                                               3 236.0 a                                                                             2 1.735 a                                                                             3 1.14 b-c                                                                            3 2.25 a-d                            2 + 8 3 16.7 a                                                                              3 0.0 a                                                                               3 214.6 a                                                                             1 1.915 a                                                                             3 0.08 c                                                                              3 0.86 c-e                            4 + 2 3 0.0 a                                                                               3 0.0 a  232.2 a                                                                             3 1.723 a                                                                             3 1.92 b-c                                                                            3 2.00 a-d                            4 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 221.8 a                                                                             3 1.903 a                                                                             3 0.42 b-c                                                                            3 1.42 b-e                            4 + 8 3 8.3 a                                                                               3 0.0 a                                                                               3 236.4 a                                                                             2 1.715 a                                                                             3 0.00 c                                                                              3 0.58 d-e                            8 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 245.3 a                                                                             3 1.714 a                                                                             3 0.67 b-c                                                                            3 1.50 a-e                            8 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 259.0 a                                                                             3 1.624 a                                                                             3 0.33 b-c                                                                            3 1.58 a-e                            8 + 8 3 0.0 a                                                                               3 0.0 a                                                                               3 248.5 a                                                                             3 1.660 a                                                                             3 0.00 c                                                                              3 0.00 e                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 6                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                         Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 8.3 b                                                                               3 0.0 b                                                                               3 254.8 a                                                                             2 1.806 a                                                                             3 0.00 c                                                                              3 0.22 c                              IC                                                                             0     3 0.0 b                                                                               3 0.0 b                                                                               3 165.6 b-c                                                                           3 2.182 a                                                                             3 8.92 a                                                                              3 3.00 a                              A82810                                                                         2     3 8.3 b                                                                               3 8.3 b                                                                               3 195.1 a-c                                                                           2 1.967 a                                                                             3 8.25 a                                                                              3 3.25 a                              4     3 8.3 b                                                                               3 0.0 b                                                                               3 189.8 a-c                                                                           2 2.083 a                                                                             3 7.39 a                                                                              3 3.19 a                              8     3 0.0 b                                                                               3 0.0 b                                                                               3 217.9 a-b                                                                           3 1.863 a                                                                             3 8.83 a                                                                              3 2.67 a                              Example No. 57                                                                 2     3 41.7 a                                                                              3 33.3 a                                                                              3 126.4 c     3 8.33 a                                                                              3 3.50 a                              4     3 8.3 b                                                                               3 8.3 b                                                                               3 177.8 a-c                                                                           2 2.048 a                                                                             3 8.25 a                                                                              3 3.08 a                              8     3 0.0 b                                                                               3 0.0 b                                                                               3 217.2 a-b                                                                           3 1.860 a                                                                             3 6.50 a-b                                                                            3 2.50 a-b                            A82810 + Example No. 57                                                        2 + 2 3 8.3 b                                                                               3 0.0 b                                                                               3 178.3 a-c                                                                           2 2.170 a                                                                             3 8.50 a                                                                              3 3.17 a                              2 + 4 3 0.0 b  0.0 b                                                                               3 221.8 a-b                                                                           3 1.840 a                                                                             3 5.67 a-b                                                                            3 3.00 a                              2 + 8 3 8.3 b                                                                               3 0.0 b                                                                               3 226.6 a-b                                                                           2 1.798 a                                                                             3 0.89 c                                                                              3 1.08 c                              4 + 2 3 8.3 b                                                                               3 0.0 b                                                                               3 226.5 a-b                                                                           2 1.728 a                                                                             3 7.50 a                                                                              3 3.06 a                              4 + 4 3 0.0 b                                                                               3 0.0 b                                                                               3 242.6 a-b                                                                           3 1.713 a                                                                             3 6.17 a-b                                                                            3 2.25 a-b                            4 + 8 3 8.3 b                                                                               3 0.0 b                                                                               3 248.1 a-b                                                                           2 1.721 a                                                                             3 0.00 c                                                                              3 0.25 c                              8 + 2 3 0.0 b                                                                               3 0.0 b                                                                               3 226.8 a-b                                                                           3 1.750 a                                                                             3 4.33 a-b                                                                            3 0.83 c                              8 + 4 3 0.0 b                                                                               3 0.0 b                                                                               3 231.5 a-b                                                                           3 1.756 a                                                                             3 2.58 b-c                                                                            3 1.42 b-c                            8 + 8 3 16.7 b                                                                              3 0.0 b                                                                               3 238.6 a-b                                                                           1 1.730 a                                                                             3 0.00 c                                                                              3 0.33 c                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 7                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                     Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 299.0 a                                                                             3 1.549 e                                                                             3 0.00 e                                                                              3 0.08 f                              IC                                                                             0     3 8.3 a                                                                               3 8.3 a                                                                               3 221.4 c-e                                                                           2 1.922 a-b                                                                           3 5.58 a                                                                              3 3.42 a                              A82810                                                                         2     3 0.0 a                                                                               3 0.0 a                                                                               3 234.4 b-e                                                                           3 1.814 a-d                                                                           3 2.83 c-d                                                                            3 2.92 a-b                            4     3 0.0 a                                                                               3 0.0 a                                                                               3 264.3 a-c                                                                           3 1.667 b-e                                                                           3 4.33 b                                                                              3 3.00 a-b                            8     3 0.0 a                                                                               3 0.0 a                                                                               3 270.5 a-c                                                                           3 1.645 c-e                                                                           3 1.67 d-e                                                                            3 3.00 a-b                            Example No. 113                                                                2     3 0.0 a                                                                               3 0.0 a                                                                               3 211.5 d-e                                                                             1.868 a-c                                                                           3 8.50 b-c                                                                            3 3.08 a-b                            4     3 0.0 a                                                                               3 0.0 a                                                                               3 251.8 a-e                                                                           3 1.685 b-e                                                                           3 0.42 e                                                                              3 2.17 b-c                            8     3 0.0 a                                                                               3 0.0 a                                                                               3 231.3 b-e                                                                           3 1.813 a-d                                                                           3 0.00 e                                                                              3 0.75 d-f                            A82810 + Example No. 113                                                       2 + 2 3 16.7 a                                                                              3 0.0 a                                                                               3 270.2 a-c                                                                           1 1.780 a-e                                                                           3 1.42 d-e                                                                            3 3.06 a-b                            2 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 257.1 a-d                                                                           3 1.712 b-e                                                                           3 0.42 e                                                                              3 1.67 c-d                            2 + 8 3 0.0 a                                                                               3 0.0 a                                                                               3 231.2 b-e                                                                           3 1.758 b-e                                                                           3 0.00 e                                                                              3 0.00 f                              4 + 2 3 8.3 a                                                                               3 0.0 a                                                                               3 267.2 a-c                                                                           2 1.590 d-e                                                                           3 0.83 e                                                                              3 2.19 b-c                            4 + 4 3 8.3 a                                                                               3 0.0 a                                                                               3 277.9 a-b                                                                           2 1.566 d-e                                                                           3 0.11 e                                                                              3 0.50 e-f                            4 + 8 3 0.0 a                                                                               3 0.0 a                                                                               3 229.5 b-e                                                                           3 1.799 a-d                                                                           3 0.00 e                                                                              3 0.42 e-f                            8 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 284.8 a                                                                             3 1.530 e                                                                             3 0.08 e                                                                              3 1.17 d-e                            8 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 267.0 a-c                                                                           3 1.629 d-e                                                                           3 0.00 e                                                                              3 0.75 d-f                            8 + 8 3 16.7 a                                                                              3 0.0 a                                                                               3 205.6 e                                                                             2 2.014 a                                                                             3 0.00 e                                                                              3 0.00 f                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 8                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                         Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 0.0 a                                                                               3 0.0 b                                                                               3 258.2 a-b                                                                           3 1.727 b                                                                             3 0.33 d                                                                              3 0.00 d                              IC                                                                             0     3 25.0 a                                                                              3 25.0 a                                                                              3 162.7 d                                                                             1 2.379 a                                                                             3 8.58 a                                                                              3 3.08 a-b                            A82810                                                                         2     3 0.0 a                                                                               3 0.0 b                                                                               3 174.8 c-d                                                                           3 2.205 a-b                                                                           3 8.83 a                                                                              3 2.92 a-b                            4     3 0.0 a                                                                               3 0.0 b                                                                               3 202.3 a-d                                                                           3 2.001 a- b                                                                          3 8.92 a                                                                              3 3.25 a                              8     3 0.0 a                                                                               3 0.0 b                                                                               3 216.0 a-d                                                                           3 1.976 a-b                                                                           3 8.42 a                                                                              3 3.33 a                              Example No. 113                                                                2     3 16.7 a                                                                              3 8.3 b                                                                               3 176.7 c-d                                                                           1 2.207 a-b                                                                           3 8.44 a                                                                              3 2.86 a-b                            4     3 8.3 a                                                                               3 0.0 b                                                                               3 231.1 a-d                                                                           2 1.789 a-b                                                                           3 7.67 a                                                                              3 2.75 a-b                            8     3 0.0 a                                                                               3 0.0 b                                                                               3 230.3 a-d                                                                           3 1.834 a-b                                                                           3 1.42 c-d                                                                            3 0.42 c-d                            A82810 + Example No. 113                                                       2 + 2 3 0.0 a                                                                               3 0.0 b                                                                               3 246.1 a-c                                                                           3 1.711 b                                                                             3 8.17 a                                                                              3 3.08 a-b                            2 + 4 3 8.3 a                                                                               3 0.0 b                                                                               3 243.9 a-c                                                                           2 1.743 a-b                                                                           3 1.42 c-d                                                                            3 1.31 c                              2 + 8 3 8.3 a                                                                               3 0.0 b                                                                               3 220.9 a-d                                                                           2 1.791 a- b                                                                          3 0.00 d                                                                              3 0.17 d                              4 + 2 3 0.0 a                                                                               3 0.0 b                                                                               3 276.3 a                                                                             3 1.636 b                                                                             3 5.25 b                                                                              3 2.08 b                              4 + 4 3 0.0 a                                                                               3 0.0 b                                                                               3 258.8 a-b                                                                           3 1.668 b                                                                             3 0.58 d                                                                              3 0.92 c-d                            4 + 8 3 0.0 a                                                                               3 0.0 b                                                                               3 232.0 a-d                                                                           3 1.776 a-b                                                                           3 0.33 d                                                                              3 0.17 d                              8 + 2 3 0.0 a                                                                               3 0.0 b                                                                               3 258.9 a-b                                                                           3 1.707 b                                                                             3 3.17 c                                                                              3 1.08 c-d                            8 + 4 3 0.0 a                                                                               3 0.0 b                                                                               3 259.3 a-b                                                                           3 1.634 b                                                                             3 0.00 d                                                                              3 0.00 d                              8 + 8 3 0.0 a                                                                               3 0.0 b                                                                               3 192.9 b-d                                                                           3 2.100 a-b                                                                           3 0.42 d                                                                              3 0.00 d                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 9                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                     Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 8.3 b                                                                               3 0.0 b                                                                               3 323.5 a                                                                             2 1.410 c                                                                             3 0.00 b                                                                              3 0.00 f                              IC                                                                             0     3 16.7 b                                                                              3 16.7 a                                                                              3 248.1 b-d                                                                           1 1.927 a-b                                                                           3 7.25 a                                                                              3 3.75 a                              A82810 + Example No. 23                                                        2 + 2 3 0.0 b                                                                               3 0.0 b                                                                               3 265.0 a-d                                                                           3 1.714 a-c                                                                           3  0.75 b                                                                             3 3.42 a                              2 + 4 3 0.0 b                                                                               3 0.0 b                                                                               3 257.9 b-d                                                                           3 1.622 b-c                                                                           3 0.17 b                                                                              3 2.00 b-c                            2 + 8 3 0.0 b                                                                               3 0.0 b                                                                               3 252.2 b-d                                                                           3 1.691 a-c                                                                           3 0.00 b                                                                              3 0.58 e-f                            4 + 2 3 8.3 b                                                                               3 8.3 b                                                                               3 292.5 a-c                                                                           2 1.482 b-c                                                                           3 0.00 b                                                                              3 1.83 b-d                            4 + 4 3 0.0 b                                                                               3 0.0 b                                                                               3 290.2 a-c                                                                           3 1.566 b-c                                                                           3 0.00 b                                                                              3 1.42 c-f                            4 + 8 3 0.0 b                                                                               3 0.0 b                                                                               3 265.3 a-d                                                                           3 1.623 b-c                                                                           3 0.00 b                                                                              3 0.42 f                              8 + 2 3 0.0 b                                                                               3 0.0 b                                                                               3 300.8 a-b                                                                           3 1.555 b-c                                                                           3 0.00 b                                                                              3 0.00 f                              8 + 4 3 0.0 b                                                                               3 0.0 b                                                                               3 292.3 a-c                                                                           3 1.565 b-c                                                                           3 0.00 b                                                                              3 0.25 f                              8 + 8 3 0.0 b                                                                               3 0.0 b                                                                               3 244.3 b-d                                                                           3 1.772 a-c                                                                           3 0.00 b                                                                              3 0.00 f                              A82810 + Example No. 39                                                        2 + 2 3 8.3 b                                                                               3 0.0 b                                                                               3 303.9 a-b                                                                           2 1.578 b-c                                                                           3 0.28 b                                                                              3 2.83 a-b                            2 + 4 3 16.7 b                                                                              3 0.0 b                                                                               3 263.3 a-d                                                                           1 1.658 a-c                                                                           3 0.00 b                                                                              3 1.75 b-e                            2 + 8 3 50.0 a                                                                              3 0.0 b                                                                               3 230.9 c-d   3 0.00 b                                                                              3 0.22 f                              4 + 2 3 0.0 b                                                                               3 0.0 b                                                                               3 280.3 a-c                                                                           3 1.554 b-c                                                                           3 0.00 b                                                                              3 1.08 c-f                            4 + 4 3 8.3 b                                                                               3 0.0 b                                                                               3 275.5 a-c                                                                           2 1.644 b-c                                                                           3 0.00 b                                                                              3 0.72 d-f                            4 + 8 3 16.7 b                                                                              3 0.0 b                                                                               3 212.2 d                                                                             2 2.025 a                                                                             3 0.00 b                                                                              3 0.00 f                              8 + 2 3 8.3 b                                                                               3 0.0 b                                                                               3 283.0 a-c                                                                           2 1.572 b-c                                                                           3 0.00 b                                                                              3 0.00 f                              8 + 4 3 16.7 b                                                                              3 0.0 b                                                                               3 273.8 a-c                                                                           1 1.804 a-c                                                                           3 0.00 b                                                                              3 0.19 f                              8 + 8 3 0.0 b                                                                               3 0.0 b                                                                               3 233.3 c-d                                                                           3 1.851 a-b                                                                           3 0.00 b                                                                              3 0.00 f                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 10                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                         Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 0.0 a                                                                               3 0.0 b                                                                               3 317.3 a                                                                             3 1.487 c-d                                                                           3 0.42 b                                                                              3 0.00 e                              IC                                                                             0     3 16.7 a                                                                              3 16.7 a                                                                              3 246.0 c-e                                                                           1 1.955 a                                                                             3 5.50 a                                                                              3 3.83 a                              A82810 + Example No. 23                                                        2 + 2 3 0.0 a                                                                               3 0.0 b                                                                               3 302.6 a-c                                                                           3 1.547 c-d                                                                           3  1.33 b                                                                             3 2.58 b                              2 + 4 3 0.0 a                                                                               3 0.0 b                                                                               3 302.8 a-c                                                                           3 1.485 c-d                                                                           3 0.83 b                                                                              3 2.00 b-c                            2 + 8 3 0.0 a                                                                               3 0.0 b                                                                               3 262.5 a-d                                                                           3 1.641 a-d                                                                           3 0.42 b                                                                              3 0.83 c-e                            4 + 2 3 0.0 a                                                                               3 0.0 b                                                                               3 307.1 a-c                                                                           3 1.456 d                                                                             3 0.83 b                                                                              3 1.58 c-d                            4 + 4 3 0.0 a                                                                               3 0.0 b                                                                               3 304.1 a-c                                                                           3 1.560 c-d                                                                           3 0.83 b                                                                              3 0.42 d-e                            4 + 8 3 0.0 a                                                                               3 0.0 b                                                                               3 263.2 a-d                                                                           3 1.640 a-d                                                                           3 0.08 b                                                                              3 0.25 b                              8 + 2 3 8.3 a                                                                               3 0.0 b                                                                               3 301.1 a-c                                                                           2 1.480 c-d                                                                           3 0.00 b                                                                              3 0.00 e                              8 + 4 3 0.0 a                                                                               3 0.0 b                                                                               3 286.3 a-c                                                                           3 1.606 b-d                                                                           3 0.33 b                                                                              3 0.00 e                              8 + 8 3 8.3 a                                                                               3 0.0 b                                                                               3 252.4 b-e                                                                           2 1.766 a-c                                                                           3 0.00 b                                                                              3 0.00 e                              A82810 + Example No. 39                                                        2 + 2 3 8.3 a                                                                               3 0.0 b                                                                               3 292.1 a-c                                                                           2 1.512 c-d                                                                           3 4.19 a                                                                              3 3.42 a                              2 + 4 3 8.3 a                                                                               3 0.0 b                                                                               3 267.8 a-d                                                                           2 1.657 a-d                                                                           3 1.61 b                                                                              3 1.19 c-e                            2 + 8 3 25.0 a                                                                              3 0.0 b                                                                               3 221.5 d-f   3 1.67 b                                                                              3 1.00 c-e                            4 + 2 3 0.0 a                                                                               3 0.0 b                                                                               3 271.3 a-d                                                                           3 1.651 a-d                                                                           3 0.42 b                                                                              3 1.00 c-e                            4 + 4 3 25.0 a                                                                              3 0.0 b                                                                               3 257.4 a-e                                                                           2 1.624 a-d                                                                           3 0.25 b                                                                              3 1.00 c-e                            4 + 8 3 41.7 a                                                                              3 0.0 b                                                                               3 186.9 f                                                                             1 1.888 a-b                                                                           3 0.33 b                                                                              3 0.33 e                              8 + 2 3 0.0 a                                                                               3 0.0 b                                                                               3 312.1 a-b                                                                           3 1.532 c-d                                                                           3 0.17 b                                                                              3 0.00 e                              8 + 4 3 25.0 a                                                                              34                                                                               0.0 b                                                                               3 275.1 a-d                                                                           1 1.616 a-d                                                                           3 0.33 b                                                                              3 0.44 d-e                            8 + 8 3 25.0 a                                                                              3 0.0 b                                                                               3 207.1 e-f                                                                           1 1.952 a                                                                             3 0.17 b                                                                              3 0.08 e                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 11                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 8.3  a  3 0.0  a  3 298.0                                                                              a-b                                                                               2 1.427                                                                              d  3 0.00                                                                               b  3 0.00                                                                               b                   IC                                                                             0     3 0.0  a  3 0.0  a  3 249.6                                                                              b-e                                                                               3 1.706                                                                              a-d                                                                               3 5.25                                                                               a  3 3.33                                                                               a                   A82810 + Example No. 113                                                       2 + 2 3 8.3  a  3 0.0  a  3 309.8                                                                              a  2 1.456                                                                              c-d                                                                               3 0.00                                                                               b  3 0.58                                                                               b                   2 + 4 3 0.0  a  3 0.0  a  3 283.8                                                                              a-c                                                                               3 1.585                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   2 + 8 3 0.0  a  3 0.0  a  3 235.2                                                                              c-e                                                                               3 1.787                                                                              a-b                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   4 + 2 3 0.0  a  3 0.0  a  3 287.3                                                                              a-b                                                                               3 1.496                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   4 + 4 3 8.3  a  3 0.0  a  3 286.4                                                                              a-c                                                                               2 1.557                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   4 + 8 3 25.0 a  3 0.0  a  3 246.3                                                                              b-e                                                                               2 1.703                                                                              a-d                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   8 + 2 3 0.0  a  3 0.0  a  3 252.7                                                                              b-e                                                                               3 1.630                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   8 + 4 3 0.0  a  3 0.0  a  3 273.8                                                                              a-d                                                                               3 1.559                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   8 + 8 3 0.0  a  3 0.0  a  3 222.7                                                                              e  3 1.736                                                                              a-d                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   A82810 + Example No. 39                                                        2 + 2 3 8.3  a  3 0.0  a  3 308.4                                                                              a  2 1.487                                                                              b-d                                                                               3 0.00                                                                               b  3 0.22                                                                               b                   2 + 4 3 8.3  a  3 0.0  a  3 255.2                                                                              b-e                                                                               2 1.630                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   2 + 8 3 8.3  a  3 0.0  a  3 213.1                                                                              e  2 1.973                                                                              a  3 0.00                                                                               b  3 0.22                                                                               b                   4 + 2 3 0.0  a  3 0.0  a  3 281.3                                                                              a-c                                                                               3 1.556                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   4 + 4 3 8.3  a  3 0.0  a  3 274.9                                                                              a-d                                                                               2 1.610                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   4 + 8 3 0.0  a  3 0.0  a  3 230.2                                                                              d-e                                                                               3 1.767                                                                              a-c                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   8 + 2 3 0.0  a  3 0.0  a  3 280.8                                                                              a-c                                                                               3 1.589                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   8 + 4 3 0.0  a  3 0.0  a  3 275.9                                                                              a-d                                                                               3 1.592                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               b                   8 + 8 3 8.3  a  3 0.0  a  3 213.9                                                                              e  2 1.954                                                                              a  3 0.00                                                                               b  3 0.00                                                                               b                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 12                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                                   Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  b  3 0.0  b  3 304.0                                                                              a-b                                                                               3 1.463                                                                              c-d                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   IC                                                                             0     3 33.3 a  3 33.3 a  3 161.9                                                                              f           3 7.75                                                                               a  3 3.67                                                                               a                   A82810 +  Example No. 113                                                      2 + 2 3 0.0  b  3 0.0  b  3 289.5                                                                              a-c                                                                               3 1.569                                                                              b-d                                                                               3 0.75                                                                               b  3 0.33                                                                               c                   2 + 4 3 0.0  b  3 0.0  b  3 300.6                                                                              a-b                                                                               3 1.451                                                                              d  3 0.00                                                                               b  3 0.00                                                                               c                   2 + 8 3 0.0  b  3 0.0  b  3 254.5                                                                              b-d                                                                               3 1.650                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   4 + 2 3 0.0  b  3 0.0  b  3 291.4                                                                              a-c                                                                               3 1.481                                                                              c-d                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   4 + 4 3 0.0  b  3 0.0  b  3 292.4                                                                              a-c                                                                               3 1.501                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   4 + 8 3 0.0  b  3 0.0  b  3 258.3                                                                              b-d                                                                               3 1.628                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   8 + 2 3 0.0  b  3 0.0  b  3 291.7                                                                              a-c                                                                               3 1.506                                                                              b-d                                                                               3 0.17                                                                               b  3 0.00                                                                               c                   8 + 4 3 0.0  b  3 0.0  b  3 276.1                                                                              a-c                                                                               3 1.555                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   8 + 8 3 0.0  b  3 0.0  b  3 253.5                                                                              b-d                                                                               3 1.660                                                                              b-c                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   A82810 + Example No. 39                                                        2 + 2 3 8.3  b  3 0.0  b  3 276.6                                                                              a-c                                                                               2 1.596                                                                              b-d                                                                               3 0.56                                                                               b  3 0.72                                                                               b                   2 + 4 3 8.3  b  3 0.0  b  3 279.4                                                                              a-c                                                                               2 1.548                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   2 + 8 3 8.3  b  3 0.0  b  3 228.2                                                                              d-e                                                                               2 1.891                                                                              a  3 0.00                                                                               b  3 0.00                                                                               c                   4 + 2 3 0.0  b  3 0.0  b  3 310.9                                                                              a  3 1.462                                                                              c-d                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   4 + 4 3 0.0  b  3 0.0  b  3 276.8                                                                              a-c                                                                               3 1.554                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   4 + 8 3 0.0  b  3 0.0  b  3 245.5                                                                              c-e                                                                               3 1.723                                                                              b  3 0.00                                                                               b  3 0.00                                                                               c                   8 + 2 3 0.0  b  3 0.0  b  3 284.5                                                                              a-c                                                                               3 1.540                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   8 + 4 3 8.3  b  3 0.0  b  3 277.6                                                                              a-c                                                                               2 1.565                                                                              b-d                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   8 + 8 3 16.7 b  3 0.0  b  3 213.1                                                                              e  1 1.782                                                                              a-b                                                                               3 0.00                                                                               b  3 0.00                                                                               c                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 13                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    3 8.3  a  3 0.0  a  3 330.7                                                                              a  2 1.448                                                                              d  3 0.00                                                                               f  3 0.00                                                                               c                   IC                                                                              0    3 0.0  a  3 0.0  a  3 250.5                                                                              d  3 1.847                                                                              a  3 7.25                                                                               a  3 3.67                                                                               a                   SALINOMYCIN                                                                      8   3 0.0  a  3 0.0  a  3 254.7                                                                              c-d                                                                               3 1.752                                                                              a-c                                                                               3 5.33                                                                               a-c                                                                               3 3.08                                                                               a-b                 16    3 8.3  a  3 0.0  a  3 279.6                                                                              b-d                                                                               2 1.620                                                                              a-d                                                                               3 2.97                                                                               c-f                                                                               3 3.72                                                                               a                   32    3 0.0  a  3 0.0  a  3 287.0                                                                              b-d                                                                               3 1.604                                                                              b-d                                                                               3 1.83                                                                               d-f                                                                               3 3.25                                                                               a-b                 Example No. 39                                                                  1    3 0.0  a  3 0.0  a  3 263.3                                                                              b-d                                                                               3 1.742                                                                              a-c                                                                               3 7.25                                                                               a  3 3.75                                                                               a                    3    3 0.0  a  3 0.0  a  3 247.0                                                                              d  3 1.851                                                                              a  3 6.17                                                                               a-b                                                                               3 3.08                                                                               a-b                  5    3 0.0  a  3 0.0  a  3 245.3                                                                              d  3 1.791                                                                              a-b                                                                               3 3.92                                                                               b-e                                                                               3 3.50                                                                               a                   SALINOMYCIN + Example No. 39                                                    8 + 1                                                                               3 0.0  a  3  0.0 a  3 270.3                                                                              b-d                                                                               3 1.706                                                                              a-d                                                                               3 4.42                                                                               b-d                                                                               3 3.75                                                                               a                    8 + 3                                                                               3 8.3  a  3 0.0  a  3 275.2                                                                              b-d                                                                               2 1.713                                                                              a-d                                                                               3 2.86                                                                               c-f                                                                               3 3.19                                                                               a-b                  8 + 5                                                                               3 0.0  a  3 0.0  a  3 266.1                                                                              b-d                                                                               3 1.684                                                                              a-d                                                                               3 2.00                                                                               d-f                                                                               3 2.83                                                                               a-b                 16 + 1                                                                               3 8.3  a  3 0.0  a  3 273.1                                                                              b-d                                                                               2 1.684                                                                              a-d                                                                               3 2.53                                                                               c-f                                                                               3 3.83                                                                               a                   16 + 3                                                                               3 0.0  a  3 0.0  a  3 284.8                                                                              b-d                                                                               3 1.599                                                                              b-d                                                                               3 1.25                                                                               e-f                                                                               3 3.33                                                                               a                   16 + 5                                                                               3 0.0  a  3 0.0  a  3 295.8                                                                              a-c                                                                               3 1.559                                                                              b-d                                                                               3 1.00                                                                               e-f                                                                               3 2.92                                                                               a-b                 32 + 1                                                                               3 8.3  a  3 0.0  a  3 296.7                                                                              a-c                                                                               2 1.536                                                                              c-d                                                                               3 1.14                                                                               e-f                                                                               3 2.67                                                                               a-b                 32 + 3                                                                               3 0.0  a  3 0.0  a  3 303.6                                                                              a-b                                                                               3 1.535                                                                              c-d                                                                               3 0.75                                                                               e-f                                                                               3 1.83                                                                               b                   32 + 5                                                                               3 0.0  a  3 0.0  a  3 298.5                                                                              a-c                                                                               3 1.568                                                                              b-d                                                                               3 0.42                                                                               f  3 0.25                                                                               c                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 14                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  a  3 0.0  a  3 319.9                                                                              a  3 1.403                                                                              c  3 0.00                                                                               d  3 0.00                                                                               e                   IC                                                                             0     3 0.0  a  3 0.0  a  3 227.6                                                                              d  3 1.837                                                                              a  3 7.50                                                                               a  3 2.92                                                                               a                   A82810 + Example No. 57                                                        2 + 2 3 0.0  a  3 0.0  a  3 262.3                                                                              b-d                                                                               3 1.622                                                                              b-c                                                                               3 4.75                                                                               b  3 2.83                                                                               a                   2 + 4 3 16.7 a  3 0.0  a  3 251.8                                                                              c-d                                                                               2 1.609                                                                              b-c                                                                               3 1.33                                                                               c-d                                                                               3 1.58                                                                               b-c                 2 + 8 3 0.0  a  3 0.0  a  3 274.6                                                                              a-d                                                                               3 1.552                                                                              b-c                                                                               3 0.00                                                                               d  3 0.75                                                                               c-e                 4 + 2 3 0.0  a  3 0.0  a  3 288.7                                                                              a-c                                                                               3 1.473                                                                              b-c                                                                               3 0.83                                                                               c-d                                                                               3 1.42                                                                               b-d                 4 + 4 3 0.0  a  3 0.0  a  3 278.9                                                                              a-c                                                                               3 1.486                                                                              b-c                                                                               3 0.33                                                                               d  3 1.50                                                                               b-c                 4 + 8 3 8.3  a  3 0.0  a  3 279.3                                                                              a-c                                                                               2 1.573                                                                              b-c                                                                               3 0.00                                                                               d  3 0.25                                                                               d-e                 8 + 2 3 0.0  a  3 0.0  a  3 304.1                                                                              a-c                                                                               3 1.419                                                                              c  3 0.00                                                                               d  3 0.17                                                                               d-e                 8 + 4 3 0.0  a  3 0.0  a  3 289.2                                                                              a-c                                                                               3 1.483                                                                              b-c                                                                               3 0.00                                                                               d  3 0.17                                                                               d-e                 8 + 8 3 25.0 a  3 0.0  a  3 269.2                                                                              a-d                                                                               1 1.541                                                                              b-c                                                                               3 0.00                                                                               d  3 0.00                                                                               e                   A82810 + Example No. 56                                                        2 + 2 3 0.0  a  3 0.0  a  3 252.2                                                                              c-d                                                                               3 1.667                                                                              b  3 5.00                                                                               b  3 3.25                                                                               a                   2 + 4 3 0.0  a  3 0.0  a  3 284.3                                                                              a-c                                                                               3 1.541                                                                              b-c                                                                               3 2.33                                                                               c  3 2.33                                                                               a-b                 2 + 8 3 0.0  a  3 0.0  a  3 264.8                                                                              b-d                                                                               3 1.587                                                                              b-c                                                                               3 0.42                                                                               d  3 1.00                                                                               c-e                 4 + 2 3 0.0  a  3 0.0  a  3 312.1                                                                              a-b                                                                               3 1.447                                                                              b-c                                                                               3 0.75                                                                               c-d                                                                               3 0.67                                                                               c-e                 4 + 4 3 0.0  a  3 0.0  a  3 295.0                                                                              a-c                                                                               3 1.460                                                                              b-c                                                                               3 0.33                                                                               d  3 1.25                                                                               b-e                 4 + 8 3 0.0  a  3 0.0  a  3 286.3                                                                              a-c                                                                               3 1.536                                                                              b-c                                                                               3 0.00                                                                               d  3 0.58                                                                               c-e                 8 + 2 3 0.0  a  3 0.0  a  3 296.8                                                                              a-c                                                                               3 1.477                                                                              b-c                                                                               3 0.00                                                                               d  3 0.25                                                                               d-e                 8 + 4 3 0.0  a  3 0.0  a  3 294.8                                                                              a-c                                                                               3 1.530                                                                              b-c                                                                               3 0.00                                                                               d  3 0.17                                                                               d-e                 8 + 8 3 0.0  a  3 0.0  a  3 263.6                                                                              b-d                                                                               3 1.577                                                                              b-c                                                                               3 0.00                                                                               d  3 0.00                                                                               e                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 15                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                                   Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  b  3 0.0  b  3 300.7                                                                              a  3 1.480                                                                              a  3 0.00                                                                               b  3 0.00                                                                               d                   IC                                                                             0     3 33.3 a  3 33.3 a  3 170.6                                                                              b           3 8.17                                                                               a  3 3.50                                                                               a                   A82810 + Example No. 57                                                        2 + 2 3 0.0  b  3 0.0  b  3 260.2                                                                              a  3 1.617                                                                              a  3 7.33                                                                               a  3 2.92                                                                               a-b                 2 + 4 3 0.0  b  3 0.0  b  3 291.5                                                                              a  3 1.484                                                                              a  3 2.50                                                                               b  3 1.50                                                                               c-d                 2 + 8 3 0.0  b  3 0.0  b  3 259.8                                                                              a  3 1.621                                                                              a  3 1.50                                                                               b  3 1.08                                                                               c-d                 4 + 2 3 0.0  b  3 0.0  b  3 285.3                                                                              a  3 1.575                                                                              a  3 6.00                                                                               a  3 2.25                                                                               b-c                 4 + 4 3 0.0  b  3 0.0  b  3 277.3                                                                              a  3 1.501                                                                              a  3 0.75                                                                               b  3 0.42                                                                               d                   4 + 8 3 0.0  b  3 0.0  b  3 262.2                                                                              a  3 1.576                                                                              a  3 0.00                                                                               b  3 0.00                                                                               d                   8 + 2 3 0.0  b  3 0.0  b  3 298.1                                                                              a  3 1.424                                                                              a  3 0.33                                                                               b  3 0.08                                                                               d                   8 + 4 3 0.0  b  3 0.0  b  3 293.8                                                                              a  3 1.474                                                                              a  3 0.00                                                                               b  3 0.00                                                                               d                   8 + 8 3 8.3  b  3 0.0  b  3 264.4                                                                              a  2 1.514                                                                              a  3 0.00                                                                               b  3 0.00                                                                               d                   A82810 + Example No. 56                                                        2 + 2 3 0.0  b  3 0.0  b  3 259.8                                                                              a  3 1.626                                                                              a  3 8.67                                                                               a  3 3.58                                                                               a                   2 + 4 3 16.7 b  3 0.0  b  3 300.2                                                                              a  1 1.449                                                                              a  3 3.56                                                                               b  3 2.31                                                                               b-c                 2 + 8 3 0.0  b  3 0.0  b  3 289.1                                                                              a  3 1.442                                                                              a  3 0.00                                                                               b  3 0.33                                                                               d                   4 + 2 3 0.0  b  3 0.0  b  3 282.5                                                                              a  3 1.475                                                                              a  3 7.42                                                                               a  3 2.17                                                                               b-c                 4 + 4 3 0.0  b  3 0.0  b  3 302.9                                                                              a  3 1.420                                                                              a  3 0.75                                                                               b  3 0.83                                                                               d                   4 + 8 3 0.0  b  3 0.0  b  3 286.3                                                                              a  3 1.516                                                                              a  3 1.50                                                                               b  3 0.25                                                                               d                   8 + 2 3 8.3  b  3 0.0  b  3 298.6                                                                              a  2 1.451                                                                              a  3 0.00                                                                               b  3 0.00                                                                               d                   8 + 4 3 0.0  b  3 0.0  b  3 293.2                                                                              a  3 1.476                                                                              a  3 0.00                                                                               b  3 0.00                                                                               d                   8 + 8 3 0.0  b  3 0.0  b  3 279.2                                                                              a  3 1.525                                                                              a  3 0.00                                                                               b  3 0.17                                                                               d                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 16                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  e  3 0.0  e  3 299.3                                                                              a  3 1.539                                                                              d  3 0.00                                                                               c  3 0.00                                                                               e                   IC                                                                             0     3 16.7 a-e                                                                               3 8.3  a-e                                                                               3 199.4                                                                              e-j                                                                               1 2.069                                                                              a-d                                                                               3 8.81                                                                               a  3 3.11                                                                               a-c                  A204                                                                          2     3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 190.3                                                                              f-j                                                                               2 2.427                                                                              a  3 7.00                                                                               a-b                                                                               3 3.58                                                                               a                   4     3 0.0  e  3 0.0  e  3 215.1                                                                              c-i                                                                               3 1.936                                                                              a-d                                                                               3 8.00                                                                               a-b                                                                               3 3.58                                                                               a                   6     3 25.0 a-c                                                                               3 16.7 a-d                                                                               3 152.5                                                                              j  1 2.215                                                                              a-b                                                                               3 7.06                                                                               a-b                                                                               3 3.75                                                                               a                   8     3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 181.6                                                                              h-j                                                                               2 2.044                                                                              a-d                                                                               3 7.58                                                                               a-b                                                                               3 3.50                                                                               a                   Example No. 56                                                                 2     3 33.3 a  3 25.0 a-b                                                                               3 178.0                                                                              i-j         3 7.53                                                                               a-b                                                                               3 3.75                                                                               a                   4     3 8.3  a-e                                                                               3 0.0  e  3 175.0                                                                              i-j                                                                               2 2.124                                                                              a-d                                                                               3 6.83                                                                               a-b                                                                               3 3.36                                                                               a-b                 6     3 25.0 a-c                                                                               3 25.0 a-b                                                                               3 206.7                                                                              d-i                                                                               1 2.110                                                                              a-d                                                                               3 6.33                                                                               a-b                                                                               3 3.67                                                                               a                   8     3 16.7 a-e                                                                               3 16.7 a-d                                                                               3 200.6                                                                              e-j                                                                               1 2.095                                                                              a-d                                                                               3 1.75                                                                               c  3 3.75                                                                               a                   A204 + Example No. 56                                                          2 + 2 3 8.3  a-e                                                                               3 0.0  e  3 188.1                                                                              g-j                                                                               2 2.128                                                                              a-d                                                                               3 8.06                                                                               a-b                                                                               3 3.36                                                                               a-b                 2 + 4 3 0.0  e  3 0.0  e  3 222.4                                                                              b-i                                                                               3 2.003                                                                              a-d                                                                               3 7.17                                                                               a-b                                                                               3 3.42                                                                               a-b                 2 + 6 3 16.7 a-e                                                                               3 0.0  e  3 216.2                                                                              c-i                                                                               1 2.172                                                                              a-c                                                                               3 6.31                                                                               a-b                                                                               3 3.61                                                                               a                   2 + 8 3 0.0  e  3 0.0  e  3 240.9                                                                              b-g                                                                               3 1.834                                                                              a-d                                                                               3 0.00                                                                               c  3 2.42                                                                               a-d                 4 + 2 3 16.7 a-e                                                                               3 8.3  a-e                                                                               3 184.8                                                                              h-j                                                                               1 2.056                                                                              a-d                                                                               3 7.42                                                                               a-b                                                                               3 3.72                                                                               a                   4 + 4 3 0.0  e  3 0.0  e  3 233.4                                                                              b-h                                                                               3 1.855                                                                              a-d                                                                               3 5.92                                                                               a-b                                                                               3 3.92                                                                               a                   4 + 6 3 8.3  a- e                                                                              3 8.3  a-e                                                                               3 240.7                                                                              b-g                                                                               2 2.050                                                                              a-d                                                                               3 0.50                                                                               c  3 2.75                                                                               a-d                 4 + 8 3 0.0  e  3 0.0  e  3 253.8                                                                              a-e                                                                               3 1.715                                                                              b-d                                                                               3 0.00                                                                               c  3 1.75                                                                               b-d                 6 + 2 3 16.7 a-e                                                                               3 8.3  a-e                                                                               3 261.3                                                                              a-d                                                                               2 1.764                                                                              a-d                                                                               3 7.11                                                                               a-b                                                                               3 3.67                                                                               a                   6 + 4 3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 247.8                                                                              b-e                                                                               2 1.874                                                                              a-d                                                                               3 1.25                                                                               c  3 2.67                                                                               a-d                 6 + 6 3 0.0  e  3 0.0  e  3 263.8                                                                              a-c                                                                               3 1.716                                                                              b-d                                                                               3 0.00                                                                               c  3 1.25                                                                               d-e                 6 + 8 3 0.0  e  3 0.0  e  3 262.5                                                                              a-d                                                                               3 1.734                                                                              b-d                                                                               3 0.00                                                                               c  3 1.25                                                                               d-e                 8 + 2 3 8.3  a-e                                                                               3 0.0  e  3 244.7                                                                              b-f                                                                               2 1.927                                                                              a-d                                                                               3 3.78                                                                               b-c                                                                               3 3.36                                                                               a-b                 8 + 4 3 8.3  a-e                                                                               3 0.0  e  3 271.4                                                                              a-c                                                                               2 1.812                                                                              a-d                                                                               3 2.50                                                                               c  3 3.25                                                                               a-b                 8 + 6 3 0.0  e  3 0.0  e  3 273.8                                                                              a-b                                                                               3 1.623                                                                              c-d                                                                               3 0.00                                                                               c  3 1.67                                                                               c-d                 8 + 8 3 0.0  e  3 0.0  e  3 240.4                                                                              b-g                                                                               3 1.924                                                                              a-d                                                                               3 0.00                                                                               c  3 1.17                                                                               d-e                 __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 17                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                                   Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 8.3  a-e                                                                               3 0.0  e  3 320.3                                                                              a  2 1.463                                                                              e  3 0.67                                                                               f  3 0.17                                                                               f                   IC                                                                             0     3 8.3  a-e                                                                               3 0.0  e  3 205.9                                                                              d-e                                                                               2 2.041                                                                              a-d                                                                               3 8.72                                                                               a  3 3.56                                                                               a-b                  A204                                                                          2     3 0.0  e  3 0.0  e  3 184.3                                                                              e  3 2.159                                                                              a-b                                                                               3 9.08                                                                               a  3 3.67                                                                               a-b                 4     3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 225.5                                                                              b-e                                                                               2 1.857                                                                              a-e                                                                               3 8.17                                                                               a  3 3.92                                                                               a                   6     3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 220.1                                                                              c-e                                                                               2 2.108                                                                              a-c                                                                               3 7.75                                                                               a  3 3.67                                                                               a-b                 8     3 0.0  e  3 0.0  e  3 255.1                                                                              a-d                                                                               3 1.751                                                                              a-e                                                                               3 9.00                                                                               a  3 3.33                                                                               a-b                 Example No. 56                                                                 2     3 0.0  e  3 0.0  e  3 207.8                                                                              d-e                                                                               3 1.929                                                                              a-e                                                                               3 8.83                                                                               a  3 3.58                                                                               a-b                 4     3 8.3  a-e                                                                               3 0.0  e  3 206.3                                                                              d-e                                                                               2 2.087                                                                              a-d                                                                               3 8.58                                                                               a  3 3.50                                                                               a-b                 6     3 0.0  e  3 0.0  e  3 203.1                                                                              d-e                                                                               3 2.192                                                                              a  3 8.42                                                                               a  3 3.67                                                                               a-b                 8     3 0.0  e  3 0.0  e  3 232.8                                                                              b-e                                                                               3 1.881                                                                              a-e                                                                               3 6.83                                                                               a-b                                                                               3 3.50                                                                               a-b                 A204 + Example No. 56                                                          2 + 2 3 0.0  e  3 0.0  e  3 235.0                                                                              b-e                                                                               3 1.955                                                                              a-d                                                                               3 8.67                                                                               a  3 3.00                                                                               a-b                 2 + 4 3 0.0  e  3 0.0  e  3 250.7                                                                              b-e                                                                               3 1.818                                                                              a-e                                                                               3 8.50                                                                               a  3 3.50                                                                               a-b                 2 + 6 3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 255.3                                                                              a-d                                                                               2 1.743                                                                              b-e                                                                               3 6.50                                                                               a-c                                                                               3 3.67                                                                               a-b                 2 + 8 3 0.0  e  3 0.0  e  3 246.3                                                                              b-e                                                                               3 1.837                                                                              a-e                                                                               3 3.17                                                                               d-f                                                                               3 1.83                                                                               c-d                 4 + 2 3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 236.7                                                                              b-e                                                                               2 1.801                                                                              a-e                                                                               3 8.17                                                                               a  3 3.58                                                                               a-b                 4 + 4 3 0.0  e  3 0.0  e  3 268.0                                                                              a-d                                                                               3 1.743                                                                              b-e                                                                               3 7.92                                                                               a  3 3.08                                                                               a-b                 4 + 6 3 0.0  e  3 0.0  e  3 269.4                                                                              a- d                                                                              3 1.728                                                                              b-e                                                                               3 4.08                                                                               b-e                                                                               3 2.17                                                                               b-d                 4 + 8 3 0.0  e  3 0.0  e  3 266.0                                                                              a-d                                                                               3 1.804                                                                              a-e                                                                               3 1.08                                                                               e-f                                                                               3 0.33                                                                               e-f                 6 + 2 3 0.0  e  3 0.0  e  3 247.5                                                                              b-e                                                                               3 1.843                                                                              a-e                                                                               3 7.58                                                                               a  3 3.25                                                                               a-b                 6 + 4 3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 281.1                                                                              a-c                                                                               2 1.685                                                                              b-e                                                                               3 4.33                                                                               b-e                                                                               3 2.75                                                                               a-c                 6 + 6 3 0.0  e  3 0.0  e  3 297.8                                                                              a-b                                                                               3 1.635                                                                              d-e                                                                               3 1.58                                                                               e-f                                                                               3 1.50                                                                               d-e                 6 + 8 3 0.0  e  3 0.0  e  3 273.3                                                                              a-d                                                                               3 1.708                                                                              b-e                                                                               3 0.50                                                                               f  3 0.50                                                                               e-f                 8 + 2 3 0.0  e  3 0.0  e  3 268.0                                                                              a-d                                                                               3 1.757                                                                              a-e                                                                               3 5.92                                                                               a-d                                                                               3 3.83                                                                               a                   8 + 4 3 0.0  e  3 0.0  e  3 281.8                                                                              a-c                                                                               3 1.636                                                                              c-e                                                                               3 3.42                                                                               c-f                                                                               3 3.42                                                                               a-b                 8 + 6 3 8.3  a-e                                                                               3 0.0  e  3 274.6                                                                              a-d                                                                               2 1.634                                                                              d-e                                                                               3 0.00                                                                               f  3 0.50                                                                               e-f                 8 + 8 3 0.0  e  3 0.0  e  3 267.4                                                                              a-d                                                                               3 1.758                                                                              a-e                                                                               3 0.00                                                                               f  3 0.33                                                                               e-f                 __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 18                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    3 0.0  e  3 0.0  e  3 308.7                                                                              a  3 1.488                                                                              c  3 0.00                                                                               g  3 0.00                                                                               d                   IC                                                                              0    3 0.0  e  3 0.0  e  3 224.2                                                                              b-e                                                                               3 1.956                                                                              a-c                                                                               3 7.92                                                                               a-b                                                                               3 3.67                                                                               a-b                 NARASIN                                                                        10    3 33.3 a  3 33.3 a  3 235.9                                                                              b-e         3 7.17                                                                               a-c                                                                               3 3.67                                                                               a-b                 20    3 16.7 a-e                                                                               3 8.3  a-e                                                                               3 194.3                                                                              d-e                                                                               1 2.162                                                                              a-b                                                                               3 6.03                                                                               a-e                                                                               3 3.64                                                                               a-b                 30    3 25.0 a-c                                                                               3 25.0 a-c                                                                               3 208.6                                                                              c-e                                                                               1 1.819                                                                              a-c                                                                               3 4.67                                                                               b-f                                                                               3 3.83                                                                               a-b                 40    3 16.7 a-e                                                                               3 16.7 a-e                                                                               3 218.5                                                                              b-e                                                                               1 1.959                                                                              a-c                                                                               3 4.50                                                                               b-f                                                                               3 3.92                                                                               a                   Example No. 56                                                                  2    3 16.7 a-e                                                                               3 16.7 a-e                                                                               3 188.3                                                                              e  1 2.049                                                                              a-c                                                                               3 8.58                                                                               a  3 3.75                                                                               a-b                  4    3 25.0 a-c                                                                               3 25.0 a-c                                                                               3 219.3                                                                              b-e         3 7.06                                                                               a-d                                                                               3 3.69                                                                               a-b                  6    3 0.0  e  3 0.0  e  3 193.4                                                                              d-e                                                                               3 2.193                                                                              a  3 5.67                                                                               a-e                                                                               3 3.42                                                                               a-b                  8    3 8.3  a-e                                                                               3 0.0  e  3 220.5                                                                              b-e                                                                               2 2.025                                                                              a-c                                                                               3 1.33                                                                               f-g                                                                               3 2.89                                                                               a-b                 NARASIN + Example No. 56                                                       10 + 2                                                                               3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 224.3                                                                              b-e                                                                               2 2.044                                                                              a-c                                                                               3 6.00                                                                               a-e                                                                               3 3.58                                                                               a-b                 10 + 4                                                                               3 8.3  a-e                                                                               3 0.0  e  3 224.4                                                                              b-e                                                                               2 1.852                                                                              a-c                                                                               3 2.14                                                                               e-g                                                                               3 3.56                                                                               a-b                 10 + 6                                                                               3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 221.8                                                                              b-e                                                                               2 1.893                                                                              a-c                                                                               3 3.42                                                                               c-g                                                                               3 3.67                                                                               a-b                 10 + 8                                                                               3 16.7 a-e                                                                               3 16.7 a-e                                                                               3 252.3                                                                              b-d                                                                               1 1.727                                                                              a-c                                                                               3 0.92                                                                               f-g                                                                               3 3.58                                                                               a-b                 20 + 2                                                                               3 0.0  e  3 0.0  e  3 225.9                                                                              b-e                                                                               3 1.907                                                                              a-c                                                                               3 3.33                                                                               c-g                                                                               3 3.42                                                                               a-b                 20 + 4                                                                               3 0.0  e  3 0.0  e  3 239.2                                                                              b-e                                                                               3 1.819                                                                              a- c                                                                              3 3.17                                                                               d-g                                                                               3 3.33                                                                               a-b                 20 + 6                                                                               3 0.0  e  3 0.0  e  3 264.0                                                                              a-c                                                                               3 1.659                                                                              b-c                                                                               3 1.17                                                                               f-g                                                                               3 3.00                                                                               a-b                 20 + 8                                                                               3 0.0  e  3 0.0  e  3 263.4                                                                              a-c                                                                               3 1.691                                                                              b-c                                                                               3 0.00                                                                               g  3 2.75                                                                               b                   30 + 2                                                                               3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 208.4                                                                              c-e                                                                               2 1.859                                                                              a-c                                                                               3 4.92                                                                               a-f                                                                               3 3.67                                                                               a-b                 30 + 4                                                                               3 0.0  e  3 0.0  e  3 264.6                                                                              a-c                                                                               3 1.732                                                                              a-c                                                                               3 1.42                                                                               f-g                                                                               3 3.75                                                                               a-b                 30 + 6                                                                               3 0.0  e  3 0.0  e  3 263.4                                                                              a-c                                                                               3 1.734                                                                              a-c                                                                               3 0.25                                                                               g  3 2.75                                                                               b                   30 + 8                                                                               3 8.3  a-e                                                                               3 0.0  e  3 249.9                                                                              b-d                                                                               2 1.690                                                                              b-c                                                                               3 0.00                                                                               g  3 1.56                                                                               c                   40 + 2                                                                               3 0.0  e  3 0.0  e  3 246.1                                                                              b-e                                                                               3 1.736                                                                              a-c                                                                               3 2.17                                                                               e-g                                                                               3 3.67                                                                               a-b                 40 + 4                                                                               3 0.0  e  3 0.0  e  3 270.1                                                                              a-b                                                                               3 1.643                                                                              b-c                                                                               3 0.92                                                                               f-g                                                                               3 3.25                                                                               a-b                 40 + 6                                                                               3 0.0  e  3 0.0  e  3 240.0                                                                              b-e                                                                               3 1.861                                                                              a-c                                                                               3 0.00                                                                               g  3 3.42                                                                               a-b                 40 + 8                                                                               3 8.3  a-e                                                                               3 0.0  e  3 261.2                                                                              a-c                                                                               2 1.804                                                                              a-c                                                                               3 0.00                                                                               g  3 1.44                                                                               c                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 19                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                                   Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    3 0.0  e  3 0.0  e  3 313.9                                                                              a  3 1.422                                                                              d  3 0.00                                                                               f  3 0.00                                                                               d                   IC                                                                              0    3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 202.3                                                                              c-e                                                                               2 1.791                                                                              a-d                                                                               3 9.00                                                                               a  3 3.67                                                                               a- b                NARASIN                                                                        10    3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 240.9                                                                              a-e                                                                               2 1.803                                                                              a-d                                                                               3 7.92                                                                               a-b                                                                               3 3.75                                                                               a-b                 20    3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 215.7                                                                              b-e                                                                               2 1.946                                                                              a-c                                                                               3 7.83                                                                               a-b                                                                               3 3.50                                                                               a-b                 30    3 0.0  e  3 0.0  e  3 227.8                                                                              b-e                                                                               3 1.778                                                                              b-d                                                                               3 7.92                                                                               a-b                                                                               3 3.92                                                                               a-b                 40    3 8.3  a-e                                                                               3 0.0  e  3 218.6                                                                              b-e                                                                               2 1.694                                                                              b-d                                                                               3 8.28                                                                               a-b                                                                               3 3.69                                                                               a-b                 Example No. 56                                                                  2    3 8.3  a-e                                                                               3 0.0  e  3 190.3                                                                              d-e                                                                               2 2.030                                                                              a-b                                                                               3 8.67                                                                               a-b                                                                               3 3.72                                                                               a-b                  4    3 0.0  e  3 0.0  e  3 190.2                                                                              e  3 2.107                                                                              a  3 8.42                                                                               a-b                                                                               3 3.75                                                                               a-b                  6    2 37.5 a  2 25.0 a  2 236.5                                                                              a-e         2 8.88                                                                               a-b                                                                               2 3.88                                                                               a-b                  8    3 0.0  e  3 0.0  e  3 224.0                                                                              b-e                                                                               3 1.922                                                                              a-c                                                                               3 8.00                                                                               a-b                                                                               3 3.83                                                                               a-b                 NARASIN + Example No. 56                                                       10 + 2                                                                               3 16.7 a-b                                                                               3 8.3  a-e                                                                               3 206.9                                                                              b-e                                                                               2 1.987                                                                              a-c                                                                               3 9.00                                                                               a  3 3.92                                                                               a-b                 10 + 4                                                                               3 0.0  e  3 0.0  e  3 244.0                                                                              a-e                                                                               3 1.699                                                                              b-d                                                                               3 6.83                                                                               a-b                                                                               3 3.50                                                                               a-b                 10 + 6                                                                               3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 250.6                                                                              a-e                                                                               2 1.704                                                                              b-d                                                                               3 5.25                                                                               a-d                                                                               3 3.92                                                                               a-b                 10 + 8                                                                               3 0.0  e  3 0.0  e  3 232.8                                                                              b-e                                                                               3 1.772                                                                              b-d                                                                               3 4.17                                                                               b-e                                                                               3 2.75                                                                               a-c                 20 + 2                                                                               3 8.3  a-e                                                                               3 0.0  e  3 203.5                                                                              b-e                                                                               2 1.783                                                                              a-d                                                                               3 8.92                                                                               a  3 3.83                                                                               a-b                 20 + 4                                                                               3 8.3  a-e                                                                               3 0.0  e  3 268.1                                                                              a-e                                                                               2 1.623                                                                              b-d                                                                               3 6.78                                                                               a- b                                                                              3 3.64                                                                               a-b                 20 + 6                                                                               3 0.0  e  3 0.0  e  3 267.2                                                                              a-e                                                                               3 1.615                                                                              c-d                                                                               3 4.17                                                                               b-e                                                                               3 3.50                                                                               a-b                 20 + 8                                                                               3 8.3  a-e                                                                               3 0.0  e  3 258.1                                                                              a-e                                                                               2 1.801                                                                              a-d                                                                               3 1.17                                                                               e-f                                                                               3 2.56                                                                               a-c                 30 + 2                                                                               3 8.3  a-e                                                                               3 0.0  e  3 229.6                                                                              b-e                                                                               2 1.746                                                                              b-d                                                                               3 8.72                                                                               a-b                                                                               3 3.75                                                                               a-b                 30 + 4                                                                               3 0.0  e  3 0.0  e  3 267.9                                                                              a-e                                                                               3 1.601                                                                              c-d                                                                               3 6.42                                                                               a-c                                                                               3 3.75                                                                               a-b                 30 + 6                                                                               3 0.0  e  3 0.0  e  3 270.9                                                                              a-e                                                                               3 1.612                                                                              c-d                                                                               3 2.00                                                                               d-f                                                                               3 2.83                                                                               a-c                 30 + 8                                                                               3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 278.4                                                                              a-b                                                                               2 1.570                                                                              c-d                                                                               3 0.92                                                                               e-f                                                                               3 2.17                                                                               c                   40 + 2                                                                               3 8.3  a-e                                                                               3 0.0  e  3 268.0                                                                              a-e                                                                               2 1.616                                                                              b-d                                                                               3 5.42                                                                               a-d                                                                               3 3.39                                                                               a-b                 40 + 4                                                                               3 0.0  e  3 0.0  e  3 265.5                                                                              a-e                                                                               3 1.547                                                                              d  3 3.00                                                                               c-f                                                                               3 3.25                                                                               a-c                 40 + 6                                                                               3 0.0  e  3 0.0  e  3 276.0                                                                              a-c                                                                               3 1.621                                                                              b-d                                                                               3 0.00                                                                               f  3 2.42                                                                               b-c                 40 + 8                                                                               3 8.3  a-e                                                                               3 0.0  e  3 271.1                                                                              a-d                                                                               2 1.580                                                                              c-d                                                                               3 0.00                                                                               f  3 0.67                                                                               d                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 20                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    3 0.0  e  3 0.0  e  3 287.3                                                                              a  3 1.598                                                                              d  3 0.00                                                                               e  3 0.00                                                                               e                   IC                                                                              0    3 8.3  a-e                                                                               3 0.0  e  3 216.7                                                                              c-e                                                                               2 1.855                                                                              a-d                                                                               3 5.42                                                                               a-c                                                                               3 3.92                                                                               a- d                NARASIN                                                                        10    3 16.7 a-c                                                                               3 0.0  e  3 221.0                                                                              b-e                                                                               1 2.028                                                                              a  3 4.28                                                                               a-d                                                                               3 4.00                                                                               a-d                 20    3 8.3  a-e                                                                               3 0.0  e  3 234.3                                                                              a-e                                                                               2 1.963                                                                              a-c                                                                               3 2.83                                                                               a-e                                                                               3 3.92                                                                               a-d                 30    3 8.3  a-e                                                                               3 0.0  e  3 250.4                                                                              a-d                                                                               2 1.849                                                                              a-d                                                                               3 2.86                                                                               a-e                                                                               3 3.64                                                                               a-d                 40    3 0.0  e  3 0.0  e  3 219.5                                                                              b-e                                                                               3 1.773                                                                              a-d                                                                               3 1.42                                                                               d-e                                                                               3 3.50                                                                               a-d                 Example No. 56                                                                  2    3 25.0 a  3 16.7 a  3 213.1                                                                              e           3 6.06                                                                               a  3 3.92                                                                               a-d                  4    3 0.0  e  3 0.0  e  3 218.8                                                                              b-e                                                                               3 2.014                                                                              a-b                                                                               3 5.67                                                                               a-b                                                                               3 4.00                                                                               a-d                  6    3 0.0  e  3 0.0  e  3 214.4                                                                              d-e                                                                               3 1.969                                                                              a-c                                                                               3 2.08                                                                               b-e                                                                               3 3.83                                                                               a-d                  8    3 0.0  e  3 0.0  e  3 225.8                                                                              b-e                                                                               3 1.990                                                                              a-c                                                                               3 0.75                                                                               d-e                                                                               3 3.17                                                                               b-d                 NARASIN + Example No. 56                                                       10 + 2                                                                               3 8.3  a-e                                                                               3 0.0  e  3 220.2                                                                              b-e                                                                               2 1.954                                                                              a-c                                                                               3 2.50                                                                               b-e                                                                               3 4.00                                                                               a-d                 10 + 4                                                                               3 0.0  e  3 0.0  e  3 241.5                                                                              a-e                                                                               3 1.850                                                                              a-d                                                                               3 2.33                                                                               b-e                                                                               3 3.67                                                                               a-d                 10 + 6                                                                               3 8.3  a-e                                                                               3 8.3  a-c                                                                               3 248.2                                                                              a-e                                                                               2 1.808                                                                              a-d                                                                               3 1.75                                                                               c-e                                                                               3 4.00                                                                               a-d                 10 + 8                                                                               3 0.0  e  3 0.0  e  3 239.8                                                                              a-e                                                                               3 1.862                                                                              a-d                                                                               3 0.42                                                                               d-e                                                                               3 2.92                                                                               d                   20 + 2                                                                               3 0.0  e  3 0.0  e  3 244.3                                                                              a-e                                                                               3 1.905                                                                              a-d                                                                               3 2.67                                                                               a-e                                                                               3 3.58                                                                               a-d                 20 + 4                                                                               3 8.3  a-e                                                                               3 0.0  e  3 240.4                                                                              a-e                                                                               2 1.923                                                                              a-d                                                                               3 2.69                                                                               a-e                                                                               3 3.78                                                                               a-d                 20 + 6                                                                               3 0.0  e  3 0.0  e  3 241.1                                                                              a-e                                                                               3 1.824                                                                              a-d                                                                               3 0.83                                                                               d-e                                                                               3 3.75                                                                               a-d                 20 + 8                                                                               3 0.0  e  3 0.0  e  3 248.0                                                                              a-e                                                                               3 1.775                                                                              a-d                                                                               3 0.67                                                                               d-e                                                                               3 3.83                                                                               a-d                 30 + 2                                                                               3 0.0  e  3 0.0  e  3 234.4                                                                              a-e                                                                               3 1.777                                                                              a-d                                                                               3 2.42                                                                               b-e                                                                               3 3.42                                                                               a-d                 30 + 4                                                                               3 8.3  a-e                                                                               3 0.0  e  3 239.8                                                                              a-e                                                                               2 1.702                                                                              c-d                                                                               3 1.81                                                                               c-e                                                                               3 3.92                                                                               a-d                 30 + 6                                                                               3 16.7 a-c                                                                               3 8.3  a-c                                                                               3 228.6                                                                              b-e                                                                               1 1.894                                                                              a-d                                                                               3 1.39                                                                               d-e                                                                               3 4.00                                                                               a-d                 30 + 8                                                                               3 0.0  e  3 0.0  e  3 235.3                                                                              a-e                                                                               3 1.837                                                                              a-d                                                                               3 0.50                                                                               d-e                                                                               3 3.08                                                                               c-d                 40 + 2                                                                               3 0.0  e  3 0.0  e  3 244.4                                                                              a-e                                                                               3 1.750                                                                              a-d                                                                               3 1.83                                                                               c-e                                                                               3 3.67                                                                               a-d                 40 + 4                                                                               3 8.3  a-e                                                                               3 0.0  e  3 234.8                                                                              a-e                                                                               2 1.887                                                                              a-d                                                                               3 1.47                                                                               d-e                                                                               3 3.92                                                                               a-d                 40 + 6                                                                               3 0.0  e  3 0.0  e  3 253.6                                                                              a-c                                                                               3 1.723                                                                              a-d                                                                               3 0.33                                                                               d-e                                                                               3 3.67                                                                               a-d                 40 + 8                                                                               3 0.0  e  3 0.0  e  3 265.4                                                                              a-b                                                                               3 1.715                                                                              b-d                                                                               3 0.17                                                                               e  3 3.58                                                                               a-d                 __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 21                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                                   Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    3 8.3  b-e                                                                               3 0.0  e  3 298.5                                                                              a  2 1.460                                                                              c  3 0.00                                                                               e  3 0.00                                                                               e                   IC                                                                              0    3 25.0 a-d                                                                               3 25.0 a-d                                                                               3 138.8                                                                              d-e         3 8.33                                                                               a-c                                                                               3 3.75                                                                               a-c                 NARASIN                                                                        10    3 0.0  e  3 0.0  e  3 148.0                                                                              d-e                                                                               3 2.458                                                                              b  3 8.75                                                                               a-c                                                                               3 3.75                                                                               a-c                 20    3 8.3  b-e                                                                               3 0.0  e  3 146.6                                                                              d-e                                                                               2 2.283                                                                              b-c                                                                               3 8.75                                                                               a-c                                                                               3 3.64                                                                               a-c                 30    3 16.7 b-e                                                                               3 16.7 a-e                                                                               3 158.2                                                                              c-e                                                                               1 2.618                                                                              b  3 8.08                                                                               a-c                                                                               3 3.67                                                                               a-c                 40    3 16.7 b-e                                                                               3 16.7 a-e                                                                               3 182.1                                                                              b-e                                                                               1 2.137                                                                              b-c                                                                               3 8.08                                                                               a-c                                                                               3 3.58                                                                               a-c                 Example No. 56                                                                  2    3 8.3  b-e                                                                               3 0.0  e  3 122.9                                                                              e  2 3.397                                                                              a  3 8.17                                                                               a-c                                                                               3 3.92                                                                               a-c                  4    3 25.0 a-d                                                                               3 25.0 a-d                                                                               3 135.6                                                                              d-e                                                                               1 2.095                                                                              b-c                                                                               3 8.92                                                                               a-c                                                                               3 3.83                                                                               a-c                  6    3 8.3  b-e                                                                               3 8.3  a-e                                                                               3 135.1                                                                              d-e                                                                               2 2.570                                                                              b  3 9.00                                                                               a  3 3.75                                                                               a-c                  8    3 0.0  e  3 0.0  e  3 200.8                                                                              b-e                                                                               3 2.071                                                                              b-c                                                                               3 8.92                                                                               a-c                                                                               3 3.58                                                                               a-c                 NARASIN + Example No. 56                                                       10 + 2                                                                               3 25.0 a-d                                                                               3 25.0 a-d                                                                               3 179.2                                                                              b-e                                                                               1 2.052                                                                              b-c                                                                               3 8.83                                                                               a-c                                                                               3 3.50                                                                               b-c                 10 + 4                                                                               3 8.3  b-e                                                                               3 8.3  a-e                                                                               3 169.8                                                                              b-e                                                                               2 2.222                                                                              b-c                                                                               3 8.50                                                                               a-c                                                                               3 3.92                                                                               a-c                 10 + 6                                                                               3 0.0  e  3 0.0  e  3 213.6                                                                              b-e                                                                               3 1.958                                                                              b-c                                                                               3 8.58                                                                               a-c                                                                               3 3.67                                                                               a-c                 10 + 8                                                                               3 0.0  e  3 0.0  e  3 218.6                                                                              b-d                                                                               3 1.872                                                                              b-c                                                                               3 8.83                                                                               a-c                                                                               3 3.50                                                                               b-c                 20 + 2                                                                               3 50.0 a  3 25.0 a-d                                                                               3 198.7                                                                              b-e         3 8.22                                                                               a-c                                                                               3 4.00                                                                               a-b                 20 + 4                                                                               3 8.3  b-e                                                                               3 8.3  a-e                                                                               3 180.3                                                                              b-e                                                                               2 1.996                                                                              b- c                                                                              3 7.67                                                                               a-c                                                                               3 3.83                                                                               a-c                 20 + 6                                                                               3 0.0  e  3 0.0  e  3 187.1                                                                              b-e                                                                               3 2.041                                                                              b-c                                                                               3 8.50                                                                               a-c                                                                               3 3.67                                                                               a-c                 20 + 8                                                                               3 0.0  e  3 0.0  e  3 216.7                                                                              b-d                                                                               3 1.857                                                                              b-c                                                                               3 6.75                                                                               b-c                                                                               3 3.00                                                                               c                   30 + 2                                                                               3 0.0  e  3 0.0  e  3 181.8                                                                              b-e                                                                               3 2.170                                                                              b-c                                                                               3 8.75                                                                               a-c                                                                               3 3.75                                                                               a-c                 30 + 4                                                                               3 8.3  b-e                                                                               3 8.3  a-e                                                                               3 219.5                                                                              b-d                                                                               2 1.803                                                                              b-c                                                                               3 8.33                                                                               a-c                                                                               3 4.00                                                                               a-b                 30 + 6                                                                               3 8.3  b-e                                                                               3 0.0  e  3 253.7                                                                              a-b                                                                               2 1.680                                                                              b-c                                                                               3 8.08                                                                               a-c                                                                               3 3.50                                                                               b-c                 30 + 8                                                                               3 8.3  b-e                                                                               3 0.0  e  3 230.3                                                                              b-d                                                                               2 1.817                                                                              b-c                                                                               3 6.14                                                                               c  3 3.58                                                                               a-c                 40 + 2                                                                               3 8.3  b-e                                                                               3 0.0  e  3 198.7                                                                              b-e                                                                               2 2.186                                                                              b-c                                                                               3 8.42                                                                               a-c                                                                               3 3.53                                                                               a-c                 40 + 4                                                                               3 0.0  e  3 0.0  e  3 208.8                                                                              b-e                                                                               3 1.832                                                                              b-c                                                                               3 8.17                                                                               a-c                                                                               3 3.75                                                                               a-c                 40 + 6                                                                               3 0.0  e  3 0.0  e  3 226.9                                                                              b-d                                                                               3 1.817                                                                              b-c                                                                               3 7.67                                                                               a-c                                                                               3 3.50                                                                               b-c                 40 + 8                                                                               3 0.0  e  3 0.0  e  3 242.8                                                                              a-c                                                                               3 1.743                                                                              b-c                                                                               3 3.17                                                                               d  3 1.83                                                                               d                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 22                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    3 0.0  e  3 0.0  e  3 286.4                                                                              a  3 1.487                                                                              d  3 0.00                                                                               e  3 0.00                                                                               f                   IC                                                                              0    3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 217.7                                                                              b-e                                                                               2 1.827                                                                              a-d                                                                               3 5.50                                                                               a-b                                                                               3 3.75                                                                               a                   NARASIN                                                                        10    3 16.7 a-d                                                                               3 16.7 a-d                                                                               3 178.0                                                                              e  2 2.100                                                                              a  3 6.17                                                                               a-b                                                                               3 3.75                                                                               a                   20    3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 188.7                                                                              d-e                                                                               2 1.725                                                                              a-d                                                                               3 4.17                                                                               a-d                                                                               3 3.42                                                                               a-c                 30    3 0.0  e  3 0.0  e  3 195.5                                                                              b-e                                                                               3 1.873                                                                              a-d                                                                               3 3.58                                                                               b-d                                                                               3 3.33                                                                               a-c                 40    3 8.3  a-e                                                                               3 0.0  e  3 232.2                                                                              a-e                                                                               2 1.757                                                                              a-d                                                                               3 2.69                                                                               c-e                                                                               3 3.81                                                                               a                   Example No. 57                                                                  2    3 16.7 a-d                                                                               3 16.7 a-d                                                                               3 195.4                                                                              c-e                                                                               1 1.911                                                                              a-d                                                                               3 6.58                                                                               a  3 3.92                                                                               a                    4    3 8.3  a-e                                                                               3 0.0  e  3 196.6                                                                              b-e                                                                               2 2.019                                                                              a-b                                                                               3 4.78                                                                               a-c                                                                               3 3.92                                                                               a                    6    3 0.0  e  3 0.0  e  3 223.1                                                                              a-e                                                                               3 1.757                                                                              a-d                                                                               3 2.08                                                                               c-e                                                                               3 3.67                                                                               a                    8    3 0.0  e  3 0.0  e  3 224.3                                                                              a-e                                                                               3 1.731                                                                              a-d                                                                               3 1.58                                                                               d-e                                                                               3 3.83                                                                               a                   NARASIN + Example No. 57                                                       10 + 2                                                                               3 25.0 a  3 25.0 a  3 213.9                                                                              b-e         3 4.00                                                                               a-d                                                                               3 3.67                                                                               a                   10 + 4                                                                               3 0.0  e  3 0.0  e  3 214.5                                                                              b-e                                                                               3 1.785                                                                              a-d                                                                               3 2.25                                                                               c-e                                                                               3 3.75                                                                               a                   10 + 6                                                                               3 16.7 a-d                                                                               3 16.7 a-d                                                                               3 248.8                                                                              a-d                                                                               2 1.689                                                                              a-d                                                                               3 0.67                                                                               e  3 3.42                                                                               a-c                 10 + 8                                                                               3 0.0  e  3 0.0  e  3 241.1                                                                              a-e                                                                               3 1.771                                                                              a-d                                                                               3 0.00                                                                               e  3 2.92                                                                               a-c                 20 + 2                                                                               3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 203.4                                                                              b-e                                                                               2 1.919                                                                              a-c                                                                               3 3.92                                                                               a-d                                                                               3 3.58                                                                               a                   20 + 4                                                                               3 0.0  e  3 0.0  e  3 241.4                                                                              a-e                                                                               3 1.683                                                                              b-d                                                                               3 0.75                                                                               e  3 3.50                                                                               a-b                 20 + 6                                                                               3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 255.4                                                                              a-d                                                                               2 1.667                                                                              b-d                                                                               3 0.08                                                                               e  3 3.42                                                                               a-c                 20 + 8                                                                               3 0.0  e  3 0.0  e  3 240.1                                                                              a-e                                                                               3 1.642                                                                              b-d                                                                               3 0.00                                                                               e  3 3.00                                                                               a-c                 30 + 2                                                                               3 0.0  e  3 0.0  e  3 243.6                                                                              a-e                                                                               3 1.645                                                                              b-d                                                                               3 1.75                                                                               d-e                                                                               3 3.67                                                                               a                   30 + 4                                                                               3 0.0  e  3 0.0  e  3 253.0                                                                              a-d                                                                               3 1.593                                                                              c-d                                                                               3 0.08                                                                               e  3 2.75                                                                               a-c                 30 + 6                                                                               3 0.0  e  3 0.0  e  3 254.6                                                                              a-d                                                                               3 1.614                                                                              c-d                                                                               3 0.08                                                                               e  3 2.42                                                                               b-d                 30 + 8                                                                               3 0.0  e  3 0.0  e  3 246.3                                                                              a-d                                                                               3 1.616                                                                              c-d                                                                               3 0.00                                                                               e  3 1.67                                                                               d-e                 40 + 2                                                                               3 0.0  e  3 0.0  e  3 239.8                                                                              a-e                                                                               3 1.645                                                                              b-d                                                                               3 1.58                                                                               d-e                                                                               3 3.67                                                                               a                   40 + 4                                                                               3 0.0  e  3 0.0  e  3 263.3                                                                              a-b                                                                               3 1.591                                                                              c-d                                                                               3 0.00                                                                               e  3 3.42                                                                               a-c                 40 + 6                                                                               3 0.0  e  3 0.0  e  3 256.5                                                                              a-d                                                                               3 1.589                                                                              c-d                                                                               3 0.00                                                                               e  3 2.33                                                                               c-d                 40 + 8                                                                               3 8.3  a-e                                                                               3 0.0  e  3 259.4                                                                              a-c                                                                               2 1.684                                                                              b-d                                                                               3 0.08                                                                               e  3 1.50                                                                               e                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 23                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                         Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    3 0.0 e                                                                               3 0.0 e                                                                               3 362.3 a                                                                             3 1.239 f                                                                             3 0.33 e                                                                              3 0.00 g                              IC    3 16.7 a-b                                                                            3 16.7 a-b                                                                            3 172.8 f                                                                             2 1.976 a                                                                             3 8.42 a                                                                              3 3.67 a-b                            NARASIN                                                                        10    3 8.3 a-e                                                                             3 8.3 a-e                                                                             3 193.8 e-f                                                                           2 1.779 a-d                                                                           3 8.42 a                                                                              3 3.83 a-b                            20    3 8.3 a-e                                                                             3 8.3 a-e                                                                             3 234.5 b-f                                                                           2 1.682 a-f                                                                           3 8.92 a                                                                              3 3.58 a-b                            30    3 8.3 a-e                                                                             3 0.0 e                                                                               3 253.0 b-e                                                                           2 1.639 a-f                                                                           3 8.75 a                                                                              3 3.64 a-b                            40    3 0.0 e                                                                               3 0.0 e                                                                               3 211.0 d-f                                                                           3 1.655 a-f                                                                           3 8.92 a                                                                              3 3.75 a-b                            Example No. 57                                                                 2     3 8.3 a-e                                                                             3 8.3 a-e                                                                             3 178.3 e-f                                                                           2 1.933 a-b                                                                           3 8.58 a                                                                              e 3.58 a-b                            4     3 0.0 e                                                                               3 0.0 e                                                                               3 212.0 d-f                                                                           3 1.793 a-c                                                                           3 8.83 a                                                                              3 3.67 a-b                            6     3 8.3 a-e                                                                             3 8.3 a-e                                                                             3 225.3 c-f                                                                           2 1.706 a-e                                                                           3 8.25 a                                                                              3 3.42 a-b                            8     3 0.0 e                                                                               3 0.0 e                                                                               3 246.6 b-f                                                                           3 1.635 a-f                                                                           3 7.58 a-b                                                                            3 3.58 a-b                            NARASIN + Example No. 57                                                       10 + 2                                                                               3 16.7 a-b                                                                            3 16.7 a-b                                                                            3 250.7 b-e                                                                           2 1.659 a-f                                                                           3 7.58 a-b                                                                            3 3.67 a-b                            10 + 4                                                                               3 0.0 e                                                                               3 0.0 e                                                                               3 241.4 b-f                                                                           3 1.544 c-f                                                                           3 7.75 a-b                                                                            3 3.50 a-b                            10 + 6                                                                               3 0.0 e                                                                               3 0.0 e                                                                               3 280.3 b-d                                                                           3 1.447 d-f                                                                           3 7.75 a-b                                                                            3 3.58 a-b                            10 + 8                                                                               3 0.0 e                                                                               3 0.0 e                                                                               3 301.3 a-c                                                                           3 1.428 d-f                                                                           3 1.67 d-e                                                                            3 1.67 d-f                            20 + 2                                                                               3 0.0 e                                                                               3 0.0 e                                                                               3 247.7 b-f                                                                           3 1.613 b-f                                                                           3 8.67 a                                                                              3 3.75 a-b                            20 + 4                                                                               3 0.0 e                                                                               3 0.0 e                                                                               3 291.6 a-d                                                                           3 1.453 d-f                                                                           3 6.50 1-c                                                                            3 2.92 a-c                            20 + 6                                                                               3 0.0 e                                                                               3 0.0 e                                                                               3 309.9 a-c                                                                           3 1.401 d-f                                                                           3 3.25 b-e                                                                            3 2.25 c-e                            20 + 8                                                                               3 0.0 e                                                                               3 0.0 e                                                                               3 303.3 a-c                                                                           3 1.429 d-f                                                                           3 1.42 d-e                                                                            3 1.42 e-f                            30 + 2                                                                               3 0.0 e                                                                               3 0.0 e                                                                               3 272.3 b-d                                                                           3 1.430 d- f                                                                          3 7.42 a-b                                                                            3 3.92 a                              30 + 4                                                                               3 8.3 a-e                                                                             3 8.3 a-e                                                                             3 294.7 a-c                                                                           2 1.495 c-f                                                                           3 3.42 b-e                                                                            3 2.58 b-d                            30 + 6                                                                               3 0.0 e                                                                               3 0.0 e                                                                               3 314.3 a-b                                                                           3 1.372 e-f                                                                           3 3.00 c-e                                                                            3 2.08 c-e                            30 + 8                                                                               3 0.0 e                                                                               3 0.0 e                                                                               3 296.4 a-c                                                                           3 1.429 d-f                                                                           3 1.17 d-e                                                                            3 0.75 f-g                            40 + 2                                                                               3 0.0 e                                                                               3 0.0 e                                                                               3 274.0 b-d                                                                           3 1.378 e-f                                                                           3 5.50 a-d                                                                            3 3.92 a                              40 + 4                                                                               3 0.o e                                                                               3 0.0 e                                                                               3 286.6 a-d                                                                           3 1.451 d-f                                                                           3 2.00 d-e                                                                            3 2.17 c-e                            40 + 6                                                                               3 0.o e                                                                               3 0.0 e                                                                               3 308.1 a-c                                                                           3 1.383 d-f                                                                           3 0.83 d-e                                                                            3 1.58 d-f                            40 + 9                                                                               3 0.o e                                                                               3 0.0 e                                                                               3 292.9 a-d                                                                           3 1.428 d-f                                                                           3 0.83 d-e                                                                            3 0.67 f-g                            __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 24                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                     Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    3 8.3 a                                                                               3 0.0 a                                                                               3 308.4 a                                                                             2 1.433 b                                                                             3 0.00 e                                                                              3 0.00 e                              IC    3 16.7 a                                                                              3 16.7 a                                                                              3 209.7 b-c                                                                           1 1.796 a-b                                                                           3 6.75 a                                                                              3 3.75 a-b                            NARASIN                                                                        60    3 16.7 a                                                                              3 16.7 a                                                                              3 258.7 a-c                                                                           2 1.693 a-b                                                                           3 2.75 b-e                                                                            3 4.00 a                              80    3 0.0 a                                                                               3 0.0 a                                                                               3 230.9 a-c                                                                           3 1.741 a-b                                                                           3 0.83 c-e                                                                            3 3.75 a-b                            Example No. 57                                                                  2    3 8.3 a                                                                               3 8.3 a                                                                               3 228.6 a-c                                                                           2 1.749 a-b                                                                           3 4.75 a-b                                                                            3 3.58 a-b                            4     3 0.0 a                                                                               3 0.0 a                                                                               3 245.9 a-c                                                                           3 1.799 a-b                                                                           3 3.17 b-d                                                                            3 3.92 a                              8     3 0.0 a                                                                               3 0.0 a                                                                               3 250.3 a-c                                                                           3 1.747 a-b                                                                           3 0.92 c-e                                                                            3 3.25 a-b                            Example No. 56                                                                 2     3 8.3 a                                                                               3 8.3 a                                                                               3 192.5 c                                                                             2 1.914 a                                                                             3 6.00 a                                                                              3 3.75 a-b                            4     3 16.7 a                                                                              3 8.3 a                                                                               3 236.2 a-c                                                                           1 1.764 a-b                                                                           3 6.92 a                                                                              3 3.75 a-b                            8     3 8.3 a                                                                               3 8.3 a                                                                               3 238.7 a-c                                                                           2 1.776 a-b                                                                           3 3.33 b-c                                                                            3 3.17 a-b                            NARASIN + Example No. 57                                                       60 + 2                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 252.0 a-c                                                                           3 1.740 a-b                                                                           3 1.33 c-e                                                                            3 3.92 a                              60 + 4                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 270.9 a-c                                                                           3 1.612 a-b                                                                           3 0.42 d-e                                                                            3 3.92 a                              60 + 8                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 266.3 a-c                                                                           3 1.640 a-b                                                                           3 0.00 e                                                                              3 1.16 d                              80 + 2                                                                               3 16.7 a                                                                              3 16.7 a                                                                              3 255.1 a-c                                                                           1 1.676 a-b                                                                           3 2.33 c-e                                                                            3 3.92 a                              80 + 4                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 253.3 a-c                                                                           3 1.648 a-b                                                                           3 0.25 e                                                                              3 3.83 a                              80 + 8                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 274.5 a-c                                                                           3 1.645 a-b                                                                           3 0.00 e                                                                              3 1.92 c                              NARASIN + Example No. 56                                                       60 + 2                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 279.5 a-b                                                                           3 1.571 a-b                                                                           3 0.92 c-e                                                                            3 3.75 a-b                            60 + 4                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 258.8 a-c                                                                           3 1.659 a-b                                                                           3 1.08 c-e                                                                            3 3.92 a                              60 + 8                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 270.8 a-c                                                                           3 1.603 a-b                                                                           3 0.08 e                                                                              3 2.67 b-c                            80 ° 2                                                                        3 8.3 a                                                                               3 8.3 a                                                                               3 240.0 a-c                                                                           2 1.769 a-b                                                                           3 2.08 c-e                                                                            3 4.00 a                              80 + 4                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 282.7 a-b                                                                           3 1.620 a-b                                                                           3 0.25 e                                                                              3 3.83 a                              80 + 8                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 272.1 a-c                                                                           3 1.610 a-b                                                                           3 0.00 e                                                                              3 2.17 c                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 25                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                         Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    3 8.3 a                                                                               3 0.0 a                                                                               3 265.5 a                                                                             2 1.432 d                                                                             3 0.00 d                                                                              3 0.00 d                              IC    3 8.3 a                                                                               3 8.3 a                                                                               3 160.9 d                                                                             2 1.880 b-c                                                                           3 8.67 a-b                                                                            3 3.83 a-b                            NARASIN                                                                        60    3 8.3 a                                                                               3 8.3 a                                                                               3 175.4 c-d                                                                           2 2.158 a-b                                                                           3 7.83 a-b                                                                            3 3.85 a-b                            80    3 25.0 a                                                                              3 25.0 a                                                                              3 212.1 a-d                                                                           1 1.774 b-d                                                                           3 5.83 a-c                                                                            3 3.58 a-b                            Example No. 57                                                                 2     3 16.7 a                                                                              3 16.7 a                                                                              3 148.3 d                                                                             1 2.528 a                                                                             3 8.25 a-b                                                                            3 3.83 a-b                            4     3 25.0 a                                                                              3 16.7 a                                                                              3 159.8 d     3 8.17 a-b                                                                            3 3.31 a-b                            8     3 0.0 a                                                                               3 0.0 a                                                                               3 201.9 a-d                                                                           3 1.795 b-d                                                                           3 4.50 a-d                                                                            3 2.33 c                              Example No. 56                                                                 2     3 16.7 a                                                                              3 16.7 a                                                                              3 146.8 d                                                                             1 2.283 a-b                                                                           3 8.17 a-b                                                                            3 3.67 a-b                            4     3 8.3 a                                                                               3 8.3 a                                                                               3 156.9 d                                                                             2 2.205 a-b                                                                           3 8.42 a-b                                                                            3 3.92 a                              8     3 8.3 a                                                                               3 8.3 a                                                                               3 158.3 d                                                                             2 2.027 b-c                                                                           3 8.92 a                                                                              3 3.67 a-b                            NARASIN + Example No. 57                                                       60 + 2                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 191.1 b-d                                                                           3 1.839 b-c                                                                           3 4.08 a-d                                                                             3                                                                               3.67 a-b                            60 + 4                                                                               3 8.3 a                                                                               3 8.3 a                                                                               3 248.0 a-b                                                                           2 1.618 c-d                                                                           3 3.58 b-d                                                                            3 3.83 a-b                            60 + 8                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 241.7 a-c                                                                           3 1.619 c-d                                                                           3 2.33 c-d                                                                            3 2.25 c                              80 + 2                                                                               3 16.7 a                                                                              3 16.7 a                                                                              3 200.8 a-d                                                                           2 1.890 b-c                                                                           3 6.00 a-c                                                                            3 3.83 a-b                            80 + 4                                                                               3 8.3 a                                                                               3 8.3 a                                                                               3 231.2 a-c                                                                           2 1.784 b-d                                                                           3 4.00 a-d                                                                            3 3.58 a-b                            80 + 8                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 238.6 a-c                                                                           3 1.624 c-d                                                                           3 0.67 d                                                                              3 2.25 c                              NARASIN + Example No. 56                                                       60 + 2                                                                               3 16.7 a                                                                              2 8.3 a                                                                               3 179.6 c-d                                                                           3 1.799 b-d                                                                           3 6.44 a-c                                                                            3 3.75 a-b                            60 + 4                                                                               3 8.3 a                                                                               3 8.3 a                                                                               3 213.1 a-d                                                                           2 1.809 b-d                                                                           3 6.42 a- c                                                                           3 3.83 a-b                            60 + 8                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 239.2 a-c                                                                           3 1.649 c-d                                                                           3 3.48 b-d                                                                            3 2.83 b-c                            80 ° 2                                                                        3 8.3 a                                                                               3 8.3 a                                                                               3 191.4 b-d                                                                           2 1.766 b-d                                                                           3 7.08 a-c                                                                            3 4.00 a                              80 + 4                                                                               3 8.3 a                                                                               3 8.3 a                                                                               3 246.6 a-b                                                                           2 1.729 c-d                                                                           3 5.22 a-c                                                                            3 3.72 a-b                            80 + 8                                                                               3 16.7 a                                                                              3 8.3 a                                                                               3 229.3 a-c                                                                           1 1.555 c-d                                                                           3 0.17 d                                                                              3 2.47 c                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 26                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                     Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    3 0.0 h                                                                               3 0.0 h                                                                               3 319.9 a                                                                             3 1.511 h                                                                             3 0.00 e                                                                              3 0.00 h                              IC    3 16.7 a-d                                                                            3 16.7 a-c                                                                            3 242.4 e-h                                                                           2 1.800 a-b                                                                           3 3.83 a                                                                              3 3.50 a-e                            A80190                                                                         4     3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 264.0 a-h                                                                           2 1.711 a-e                                                                           3 3.58 a                                                                              3 3.67 a-e                            8     3 16.7 a-d                                                                            3 16.7 a-c                                                                            3 261.1 a-h                                                                           1 1.511 h                                                                             3 3.67 a                                                                              3 3.33 a-e                            16    3 0.0 h                                                                               3 0.0 h                                                                               3 267.8 a-h                                                                           3 1.621 a-h                                                                           3 1.83 a-e                                                                            3 3.67 a-e                            Example No. 57                                                                 2     3 0.0 h                                                                               3 0.0 h                                                                               3 253.4 b-h                                                                           3 1.647 a-h                                                                           3 3.08 a-b                                                                            3 3.67 a-e                            4     3 0.0 h                                                                               3 0.0 h                                                                               3 251.5 c-h                                                                           3 1.668 a-g                                                                           3 3.17 a-b                                                                            3 3.42 a-e                            8     3 0.0 h                                                                               3 0.0 h                                                                               3 249.8 d-h                                                                           3 1.665 a-h                                                                           3 1.42 a-e                                                                            3 3.60 a-e                            Example No. 56                                                                 2     3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 238.8 f-h                                                                           2 1.794 a-c                                                                           3 3.75 a                                                                              3 3.25 a-e                            4     3 8.3 a-h                                                                             3 0.0 h                                                                               3 273.1 a-h                                                                           2 1.628 a-h                                                                           3 3.00 a-c                                                                            3 3.61 a-e                            8     3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 267.1 a-h                                                                           2 1.651 a-h                                                                           3 2.25 a-e                                                                            3 3.08 a-e                             A80190 + Example No. 57                                                       4 + 2 3 0.0 h                                                                               3 0.0 h                                                                               3 220.5 h                                                                             3 1.810 a                                                                             3 2.67 a-d                                                                            3 3.67 a-e                            4 + 4 3 16.7 a-d                                                                            3 16.7 a-c                                                                            3 272.6 a-h                                                                           1 1.538 e-h                                                                           3 3.17 a-b                                                                            3 3.67 a-e                            4 + 8 3 0.0 h                                                                               3 0.0 h                                                                               3 277.3 a-h                                                                           3 1.622 a-h                                                                           3 0.00 e                                                                              3 2.00 e-g                            8 + 2 3 0.0 h                                                                               3 0.0 h                                                                               3 297.3 a-c                                                                           3 1.531 f-h                                                                           3 2.00 a-e                                                                            3 3.75 a-c                            8 + 4 3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 283.5 a-g                                                                           2 1.545 c-h                                                                           3 1.67 a-e                                                                            3 3.00 b-e                            8 + 8 3 0.0 h                                                                               3 0.0 h                                                                               3 281.9 a-h                                                                           3 1.595 a-h                                                                           3 0.25 d-e                                                                            3 2.00 e-g                            16 + 2                                                                               3 0.0 h                                                                               3 0.0 h                                                                               3 271.5 a-h                                                                           3 1.620 a-h                                                                           3 0.83 b-e                                                                            3 3.42 a-e                            16 + 4                                                                               3 0.0 h                                                                               3 0.0 h                                                                               3 295.2 a-d                                                                           3 1.537 e-h                                                                           3 1.50 a-e                                                                            3 3.42 a-e                            16 + 8                                                                               3 8.3 a-h                                                                             3 0.0 h                                                                               3 287.7 a-f                                                                           2 1.598 a-h                                                                           3 0.00 e                                                                              3 0.81 g-h                            A80190 + Example No. 56                                                        4 + 2 3 8.3 a-h                                                                             3 8.3 a-h                                                                             2 265.6 a-h                                                                           2 1.659 a-h                                                                           3 3.33 a-b                                                                            3 3.50 a-e                            4 + 4 3 0.0 h                                                                               3 0.0 h                                                                               3 257.3 a-h                                                                           3 1.697 a-f                                                                           3 2.50 a-e                                                                            3 3.92 a                              4 + 8 3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 265.8 a-h                                                                           2 1.591 a-h                                                                           3 1.83 a-e                                                                            3 3.76 a-c                            8 + 2 3 0.0 h                                                                               3 0.0 h                                                                               3 231.4 g-h                                                                           3 1.766 a-d                                                                           3 2.08 a-e                                                                            3 .333 a-e                            8 + 4 3 0.0 h                                                                               3 0.0 h                                                                               3 259.6 a-h                                                                           3 1.624 a- h                                                                          3 1.33 a-e                                                                            3 3.50 a-e                            8 + 8 3 0.0 h                                                                               3 0.0 h                                                                               3 268.2 a-h                                                                           3 1.644 a-h                                                                           3 1.50 a-e                                                                            3 2.67 c-f                            16 + 2                                                                               3 16.7 a-d                                                                            3 8.3 a-h                                                                             3 291.8 a-e                                                                           1 1.622 a-h                                                                           3 1.25 a-e                                                                            3 3.33 a-e                            16 + 4                                                                               3 0.0 h                                                                               3 0.0 h                                                                               3 281.7 a-h                                                                           3 1.585 a-h                                                                           3 0.92 b-e                                                                            3 3.08 a-e                            16 + 8                                                                               3 0.0 h                                                                               3 0.0 h                                                                               3 299.0 a-b                                                                           3 1.556 b-h                                                                           3 0.42 c-e                                                                            3 1.58 f-g                            __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 27                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                         Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 0.0 h                                                                               3 0.0 h                                                                               3 271.4 a                                                                             3 1.522 h                                                                             3 0.00 f                                                                              3 0.00 g                              IC                                                                             0     3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 151.7 h                                                                             2 2.374 a                                                                             3 7.67 a-d                                                                            3 3.42 a-d                            A80190                                                                         4     3 0.0 h                                                                               3 0.0 h                                                                               3 199.9 a-h                                                                           3 1.903 b-e                                                                           3 8.17 a-d                                                                            3 3.58 a-d                            8     3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 190.1 b-h                                                                           2 1.791 b-h                                                                           3 8.50 a-d                                                                            3 3.75 a-d                            16    3 0.0 h                                                                               3 0.0 h                                                                               3 190.8 a-h                                                                           3 1.882 b-f                                                                           3 8.00 a-d                                                                            3 3.75 a-d                            Example No. 57                                                                 2     3 16.7 a-e                                                                            3 8.3 a-h                                                                             3 171.1 f-h                                                                           1 1.610 c-h                                                                           3 9.22 a                                                                              3 4.00 a                              4     3 8.3 a-h                                                                             3 0.0 h                                                                               3 218.6 a-h                                                                           2 1.688 b-h                                                                           3 8.50 a-d                                                                            3 3.75 a-d                            8     3 0.0 h                                                                               3 0.0 h                                                                               3 223.8 a-h                                                                           3 1.689 b-h                                                                           3 6.42 a-d                                                                            3 2.92 a-d                            Example No. 56                                                                 2     3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 164.4 g-h                                                                           2 2.079 a-b                                                                           3 8.00 a-d                                                                            3 3.67 a-d                            4     3 0.0 h                                                                               3 0.0 h                                                                               3 182.6 e-h                                                                           3 1.949 b-c                                                                           3 8.33 a-d                                                                            3 3.75 a-d                            8     3 0.0 h                                                                               3 0.0 h                                                                               3 224.0 a-h                                                                           3 1.670 b-h                                                                           3 6.25 a-d                                                                            3 3.33 a-d                            A80190 + Example No. 57                                                        4 + 2 3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 188.4 d-h                                                                           2 1.924 b-d                                                                           3 7.02 a-d                                                                            3 3.58 a-d                            4 + 4 3 16.7 a-e                                                                            3 8.3 a-h                                                                             3 204.8 a-h                                                                           2 1.793 b-h                                                                           3 6.08 b-d                                                                            3 3.67 a-d                            4 + 8 3 8.3 a-h                                                                             3 0.0 h                                                                               3 229.2 a-h                                                                           2 1.623 b-h                                                                           3 3.92 d-e                                                                            3 2.78 c-d                            8 + 2 3 0.0 h                                                                               3 0.0 h                                                                               3 199.9 a-h                                                                           3 1.817 b-h                                                                           3 8.83 a-b                                                                            3 3.58 a-d                            8 + 4 3 16.7 a-e                                                                            3 16.7 a-b                                                                            3 239.6 a-f                                                                           1 1.567 e-h                                                                           3 6.42 a-d                                                                            3 3.33 a-d                            8 + 8 3 0.0 h                                                                               3 0.0 h                                                                               3 260.8 a-b                                                                           3 1.549 g-h                                                                           3 1.33 e-f                                                                            3 1.83 e-f                            16 +  2                                                                              3 8.3 a-b                                                                             3 8.3 a-h                                                                             3 228.4 a-h                                                                           2 1.739 b-h                                                                           3 6.83 a-d                                                                            3 3.42 a-d                            16 + 4                                                                               3 0.0 h                                                                               3 0.0 h                                                                               3 238.3 a-g                                                                           3 1.660 b-h                                                                           3 7.08 a-d                                                                            3 3.42 a-d                            16 + 8                                                                               3 0.0 h                                                                               3 0.0 h                                                                               3 237.5 a-g                                                                           3 1.562 f-h                                                                           3 0.83 e-f                                                                            3 1.25 f                              A80190 + Example No. 56                                                        4 + 2 3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 190.1 c-h                                                                           2 1.841 b-g                                                                           3 6.92 a-d                                                                            3 2.83 b-d                            4 + 4 3 0.0 h                                                                               3 0.0 h                                                                               3 230.1 a-h                                                                           3 1.638 b-h                                                                           3 8.17 a-d                                                                            3 3.08 a-d                            4 + 8 3 8.3 a-h                                                                             3 0.0 h                                                                               3 241.4 a-d                                                                           2 1.586 d-h                                                                           3 6.97 a-d                                                                            3 3.36 a-d                            8 + 2 3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 199.2 a-h                                                                           2 1.828 b-h                                                                           3 7.42 a-d                                                                            3 3.75 a-d                            8 + 4 3 0.0 h                                                                               3 0.0 h                                                                               3 212.1 a-h                                                                           3 1.714 b-h                                                                           3 8.00 a-d                                                                            3 3.58 a-d                            8 + 8 3 0.0 h                                                                               3 0.0 h                                                                               3 240.1 a-e                                                                           3 1.615 b-h                                                                           3 4.00 c-e                                                                            3 2.50 d-e                            16 + 2                                                                               3 16.7 a-e                                                                            3 16.7 a-b                                                                            3 238.0 a-g                                                                           2 1.691 b-h                                                                           3 7.50 a-d                                                                            3 3.67 a-d                            16 + 4                                                                               3 0.0 h                                                                               3 0.0 h                                                                               3 236.4 a-g                                                                           3 1.640 b-h                                                                           3 7.17 a-d                                                                            3 3.50 a-d                            16 + 8                                                                               3 16.7 a-e                                                                            3 8.3 a-h                                                                             3 256.3 a-c                                                                           2 1.622 b-h                                                                           3 1.75 e-f                                                                            3 1.69 e-f                            __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 28                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                     Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 0.0 h                                                                               3 0.0 h                                                                               3 308.2 a                                                                             3 1.475 c-d                                                                           3 0.00 h                                                                              3 0.00 f                              IC                                                                             0     3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 214.7 e-h                                                                           2 1.872 b                                                                             3 6.33 a-b                                                                            3 3.58 a-b                            A80190                                                                         4     3 33.3 a                                                                              3 25.0 a-d                                                                            3 193.0 g-h   3 7.00 a                                                                              3 3.44 a-b                            8     3 16.7 a-h                                                                            3 0.0 h                                                                               3 274.0 a- f                                                                          1 1.570 b-d                                                                           3 4.39 a-e                                                                            3 2.83 a-b                            16    3 25.0 a-e                                                                            3 16.7 a-g                                                                            3 212.0 f-h                                                                           2 1.590 b-d                                                                           3 3.61 a-h                                                                            3 2.89 a-b                            Example No. 57                                                                 2     3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 168.0 h                                                                             2 2.331 a                                                                             3 4.00 a-f                                                                            3 3.50 a-b                            4     3 16.7 a-h                                                                            3 16.7 a-g                                                                            3 222.2 c-h                                                                           2 1.922 b                                                                             3 5.08 a-c                                                                            3 3.58 a-b                            8     3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 261.3 a-f                                                                           2 1.541 c-d                                                                           3 2.42 c-h                                                                            3 3.08 a-b                            Example No. 56                                                                 2     3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 242.9 a-g                                                                           2 1.888 b                                                                             3 4.75 a-d                                                                            3 3.67 a-b                            4     3 16.7 a-h                                                                            3 16.7 a-g                                                                            3 217.8 d-h                                                                           1 1.622 b-d                                                                           3 5.42 a-c                                                                            3 3.42 a-b                            8     3 16.7 a-h                                                                            3 8.3 a-h                                                                             3 226.8 b-g                                                                           2 1.726 b-d                                                                           3 3.75 a-g                                                                            3 3.19 a-b                            A80190 + Example No. 57                                                        4 + 2 3 25.0 a-e                                                                            3 25.0 a-d                                                                            3 245.4 a-g                                                                           1 1.814 b-c                                                                           3 4.94 a-c                                                                            3 3.56 a-b                            4 + 4 3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 262.9 a-f                                                                           2 1.684 b-d                                                                           3 3.25 b-h                                                                            3 3.33 a-b                            4 + 8 3 0.0 h                                                                               3 0.0 h                                                                               3 282.8 a-e                                                                           3 1.584 b-d                                                                           3 0.08 h                                                                              3 2.25 b-d                            8 + 2 3 25.0 a-e                                                                            3 25.0 a-d                                                                            3 243.0 a-g   3 3.92 a-f                                                                            3 3.42 a-b                            8 + 4 3 8.3 a-h                                                                             3 0.0 h                                                                               3 271.7 a-f                                                                           2 1.609 b-d                                                                           3 1.19 e-h                                                                            3 3.03 a-b                            8 + 8 3 8.3 a-h                                                                             3 0.0 h                                                                               3 275.1 a-f                                                                           2 1.570 b-d                                                                           3 0.00 h                                                                              3 1.36 c-e                            16 + 2                                                                               3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 255.9 a-g                                                                           2 1.725 b-d                                                                           3 3.08 b-h                                                                            3 3.33 a-b                            16 + 4                                                                               3 0.0 h                                                                               3 0.0 h                                                                               23                                                                               289.6 a-b                                                                           3 1.543 c-d                                                                           3 0.00 h                                                                              3 1.25 d-e                            16 + 8                                                                               3 0.0 h                                                                               3 0.0 h                                                                               3 282.4 a-f                                                                           3 1.619 b-d                                                                           3 0.00 h                                                                              3 0.17 f                              A80190 + Example No. 56                                                        4 + 2 3 25.0 a-d                                                                            3 25.0 a-d                                                                            3 249.5 a-g                                                                           1 1.468 d                                                                             3 5.17 a-c                                                                            3 3.42 a-b                            4 + 4 3 0.0 h                                                                               3 0.0 h                                                                               3 273.3 a-f                                                                           3 1.589 b-d                                                                           3 2.75 b-h                                                                            3 3.25 a-b                            4 + 8 3 8.3 a-h                                                                             3 0.0 h                                                                               3 237.5 a-g                                                                           2 1.663 b-d                                                                           3 1.00 e-h                                                                            3 2.94 a-b                            8 + 2 3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 243.8 a-g                                                                           2 1.787 b-d                                                                           3 3.33 b- h                                                                           3 3.67 a-b                            8 + 4 3 8.3 a-h                                                                             3 8.3 a-h                                                                             3 246.1 a-g                                                                           2 1.661 b-d                                                                           3 3.25 b-h                                                                            3 3.33 a-b                            8 + 8 3 0.0 h                                                                               3 0.0 h                                                                               3 270.0 a-f                                                                           3 1.550 c-d                                                                           3 0.58 f-h                                                                            3 2.42 a-c                            16 + 2                                                                               3 0.0 h                                                                               3 0.0 h                                                                               3 272.7 a-f                                                                           3 1.580 b-d                                                                           3 1.33 d-h                                                                            3 2.42 a-c                            16 + 4                                                                               3 0.0 h                                                                               3 0.0 h                                                                               3 289.3 a-c                                                                           3 1.480 c-d                                                                           3 0.42 f-h                                                                            3 1.50 c-e                            16 + 8                                                                               3 0.0 h                                                                               3 0.0 h                                                                               3 283.8 a-c                                                                           3 1.494 c-d                                                                           3 0.25 g-h                                                                            3 0.83 e-f                            __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 29                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                         Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 0.0 h                                                                               3 0.0 h                                                                               3 320.3 a                                                                             3 1.523 d-e                                                                           3 0.00 g                                                                              3 0.00 g                              IC                                                                             0     3 16.7 a-h                                                                            3 16.7 a-h                                                                            3 182.6 h-j                                                                           2 1.973 -b                                                                            3 9.08 a                                                                              3 3.75 a-e                            A80190                                                                         4     3 25.0 a-h                                                                            3 25.0 a-g                                                                            3 217.8 c-j                                                                           2 1.883 a-e                                                                           3 9.00 a                                                                              3 3.75 a-e                            8     3 25.0 a-h                                                                            3 25.0 a- g                                                                           3 213.1 c-j                                                                           2 1.955 a-c                                                                           3 7.50 a-d                                                                            3 3.83 a-e                            16    3 25.0 a-h                                                                            3 16.7 a-h                                                                            3 208.4 d-j                                                                           1 1.943 a-d                                                                           3 7.75 a-d                                                                            3 4.00 a                              Example No. 57                                                                 2     3 25.0 a-h                                                                            3 25.0 a-g                                                                            3 161.4 j                                                                             1 2.083 a                                                                             3 8.58 a-b                                                                            3 3.83 a-e                            4     3 41.7 a-b                                                                            3 33.3 a-b                                                                            3 172.2 i-j   3 7.89 a-d                                                                            3 3.56 a-e                            8     3 8.3 b-h                                                                             3 8.3 a-h                                                                             3 237.4 b-j                                                                           2 1.793 a-e                                                                           3 7.17 a-d                                                                            3 3.67 a-e                            Example No. 56                                                                 2     3 25.0 a-h                                                                            3 25.0 a-g                                                                            3 173.8 i-j                                                                           1 1.789 a-e                                                                           3 7.42 a-d                                                                            3 3.75 a-e                            4     3 50.0 a                                                                              3 50.0 a                                                                              3 192.9 f-j   3 7.25 a-d                                                                            3 3.83 a-e                            8     3 0.0 h                                                                               3 0.0 h                                                                               3 190.1 g-j                                                                           3 2.087 a                                                                             3 6.83 a-e                                                                            3 3.33 a-e                            A80190 + Example No. 57                                                        4 + 2 3 25.0 a-h                                                                            3 25.0 a-g                                                                            3 216.5 c-j                                                                           1 1.701 a-e                                                                           3 8.25 a-c                                                                            3 3.92 a-b                            4 + 4 3 8.3 b-h                                                                             3 8.3 a-h                                                                             3 239.4 b-j                                                                           2 1.820 a-e                                                                           3 6.00 a-e                                                                            3 3.67 a-e                            4 + 8 3 0.0 h                                                                               3 0.0 h                                                                               3 270.4 a-f                                                                           3 1.616 b-e                                                                           3 0.17 g                                                                              3 3.17 a-e                            8 + 2 3 25.0 a-h                                                                            3 8.3 a-h                                                                             3 221.0 c-j                                                                           1 1.831 a-e                                                                           3 7.69 a-d                                                                            3 3.89 a-c                            8 + 4 3 16.7 a-h                                                                            3 8.3 a-h                                                                             3 250.7 a-i                                                                           1 1.709 a-e                                                                           3 4.56 b-f                                                                            3 3.72 a-e                            8 + 8 3 0.0 h                                                                               3 0.0 h                                                                               3 287.0 a-d                                                                           3 1.554 d-e                                                                           3 0.33 g                                                                              3 2.08 e-f                            16 +  2                                                                              3 16.7 a-h                                                                            3 16.7 a-h                                                                            3 275.2 a-e                                                                           1 1.628 a-e                                                                           3 4.25 c-f                                                                            3 2.75 b-e                            16 + 4                                                                               3 16.7 a-h                                                                            3 8.3 a-h                                                                             3 263.4 a-g                                                                           1 1.649 a-e                                                                           3 3.17 e-g                                                                            3 2.94 a-e                            16 + 8                                                                               3 8.3 b-h                                                                             3 0.0 h                                                                               3 291.4 a-c                                                                           2 1.557 c-e                                                                           3 0.00 g                                                                              3 0.44 g                              A80190 + Example No. 56                                                        4 + 2 3 25.0 a-h                                                                            3 16.7 a-h                                                                            3 218.1 c-j                                                                           1 1.723 a-e                                                                           3 8.39 a-c                                                                            3 3.44 a-e                            4 + 4 3 16.7 a-h                                                                            3 16.7 a-h                                                                            3 232.5 b-j                                                                           1 1.873 a-e                                                                           3 7.75 a-d                                                                            3 3.75 a-e                            4 + 8 3 8.3 b-h                                                                             3 8.3 a-h                                                                             3 260.9 a-h                                                                           2 1.584 b-e                                                                           3 4.00 d-f                                                                            3 3.50 a-e                            8 + 2 3 8.3 b-h                                                                             3 8.3 a-h                                                                             3 206.1 e-j                                                                           2 1.873 a-e                                                                           3 8.08 a-d                                                                            3 3.58 a-e                            8 + 4 3 0.0 h                                                                               3 0.0 h                                                                               3 230.4 c-j                                                                           3 1.752 a-e                                                                           3 5.58 a-e                                                                            3 3.58 a-e                            8 + 8 3 0.0 h                                                                               3 0.0 h                                                                               3 292.6 a-c                                                                           3 1.517 e                                                                             3 1.42 f-g                                                                            3 2.08 e-f                            16 + 2                                                                               3 8.3 b-h                                                                             3 8.3 a-h                                                                             3 248.7 a-i                                                                           2 1.744 a-e                                                                           3 5.25 a-e                                                                            3 3.25 a-e                            16 + 4                                                                               3 8.3 b-h                                                                             3 0.0 h                                                                               3 267.5 a-g                                                                           2 1.542 d-e                                                                           3 3.22 e-g                                                                            3 2.47 c-f                            16 + 8                                                                               3 8.3 b-h                                                                             3 0.0 h                                                                               3 308.1 a-b                                                                           2 1.537 d-e                                                                           3 0.17 g                                                                              3 1.17 f-g                            __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 30                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                     Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     4 0.0 e                                                                               4 0.0 a                                                                               4 330.6 a                                                                             4 1.394 d                                                                             4 0.00 f                                                                              4 0.00 e                              IC                                                                             0     4 0.0 e                                                                               4 0.0 a                                                                               4 276.3 d-e                                                                           4 1.641 a-b                                                                           4 5.88 a                                                                              4 3.56 a-b                            A80190                                                                         10    4 0.0 e                                                                               4 0.0 a                                                                               4 293.4 a-e                                                                           4 1.515 a-d                                                                           4 5.19 a-b                                                                            4 3.00 a-c                            20    4 0.0 e                                                                               4 0.0 a                                                                               4 300.4 a-e                                                                           4 1.449 c-d                                                                           4 3.56 b-d                                                                            4 3.00 a-c                            30    4 12.5 a-c                                                                            4 0.0 a                                                                               4 313.9 a-c                                                                           3 1.450 c-d                                                                           4 2.06 d-f                                                                            4 3.00 a-c                            40    4 0.0 e                                                                               4 0.0 a                                                                               4 321.9 a-b                                                                           4 1.391 d                                                                             4 2.38 c-e                                                                            4 2.44 a-c                            Example No. 57                                                                 2     4 0.0 e                                                                               4 0.0 a                                                                               4 270.8 e                                                                             4 1.662 a                                                                             4 5.81 a                                                                              4 3.69 a                              4     4 0.0 e                                                                               4 0.0 a                                                                               4 284.4 a-e                                                                           4 1.583 a-c                                                                           4 4.81 a-b                                                                            4 3.56 a-b                            6     4 0.0 e                                                                               4 0.0 a                                                                               4 277.8 b-e                                                                           4 1.568 a-d                                                                           4 4.75 a-b                                                                            4 2.38 a-c                            8     4 12.5 a-c                                                                            4 0.0 a                                                                               4 277.2 b-e                                                                           2 1.617 a-c                                                                           4 4.06 a-c                                                                            4 2.48 a-c                            A80190 + Example No. 57                                                        10 + 2                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 283.6 a-e                                                                           4 1.543 a-d                                                                            4                                                                               4.06 a-c                                                                            4 3.13 a-c                            10 + 4                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 301.3 a-e                                                                           4 1.437 c-d                                                                           4 2.44 c-e                                                                            4 2.69 a-c                            10 + 6                                                                               4 6.3 a-e                                                                             4 0.0 a                                                                               4 276.5 b-e                                                                           3 1.559 a-d                                                                           4 2.04 d-f                                                                            4 2.29 b-c                            10 + 8                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 280.6 a-e                                                                           4 1.566 a-d                                                                           4 1.19 e-f                                                                            4 1.00 d-e                            20 + 2                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 306.9 a-e                                                                           4 1.430 c-d                                                                           4 1.63 e-f                                                                            4 2.56 a-c                            20 + 4                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 291.8 a-e                                                                           4 1.514 a-d                                                                           4 1.69 e-f                                                                            4 1.75 c-d                            20 + 6                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 289.5 a-e                                                                           4 1.508 a-d                                                                           4 0.88 e-f                                                                            4 1.00 d-e                            20 + 8                                                                               4 6.3 a-e                                                                             4 0.0 a                                                                               4 276.5 c-e                                                                           3 1.498 a-d                                                                           4 0.29 f                                                                              4 1.13 d-e                            30 + 2                                                                               4 12.5 a-c                                                                            4 0.0 a                                                                               4 296.3 a-e                                                                           2 1.487 a-d                                                                           4 1.71 e-f                                                                            4 2.52 a-c                            30 + 4                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 289.7 a-e                                                                           4 1.504 a-d                                                                           4 1.06 e-f                                                                            4 1.13 d-e                            30 + 6                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 303.2 a-e                                                                           4 1.520 a-d                                                                           4 0.25 f                                                                              4 0.56 d-e                            30 + 8                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 278.3 b-e                                                                           4 1.528 a-d                                                                           4 0.19 f                                                                              4 0.44 e                              40 + 2                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 303.3 a-e                                                                           4 1.448 c-d                                                                           4 0.81 e-f                                                                            4 1.75 c-d                            40 + 4                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 311.1 a-d                                                                           4 1.451 b-d                                                                           4 0.06 f                                                                              4 0.19 e                              40 + 6                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 286.8 a-e                                                                           4 1.571 a-d                                                                           4 0.19 f                                                                              4 0.25 e                              40 + 8                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 296.6 a-e                                                                           4 1.475 b-d                                                                           4 0.00 f                                                                              4 0.00 e                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 31                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                     Lesion Scores                                Treatment                                                                            Mortality                                                                             Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     4 0.0 e                                                                               4 0.0 e                                                                               4 332.1 a                                                                             4 1.439 f                                                                             4 0.00 g                                                                              4 0.00 g                              IC                                                                             0     4 0.0 e                                                                               4 0.0 e                                                                               4 283.9 a-e                                                                           4 1.688 a-c                                                                           4 5.56 a                                                                              4 3.00 a-c                            A80190 + Example No. 57                                                        2 + 2 4 6.3 a-e                                                                             4 0.0 e                                                                               4 285.4 a-e                                                                           3 1.621 a-f                                                                            4                                                                               5.31 a                                                                              4 3.21 a-b                            2 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 280.3 a-e                                                                           4 1.758 a                                                                             4 3.94 a-c                                                                            4 3.13 a-c                            2 + 8 4 0.0 e                                                                               4 0.0 e                                                                               4 280.8 a-e                                                                           4 1.637 a-e                                                                           4 2.31 c-g                                                                            4 2.00 b-d                            4 + 2 4 0.0 e                                                                               4 0.0 e                                                                               4 285.4 a-e                                                                           4 1.657 a-d                                                                           4 4.69 a-b                                                                            4 3.06 a-c                            4 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 301.2 a-e                                                                           4 1.545 c-f                                                                           4 3.50 a-d                                                                            4 3.50 a                              4 + 8 4 0.0 e                                                                               4 0.0 e                                                                               4 289.6 a-e                                                                           4 1.605 a-f                                                                           4 1.25 d-g                                                                            4 1.38 d-f                            8 + 2 4 0.0 e                                                                               4 0.0 e                                                                               4 284.8 a-e                                                                           4 1.604 a-f                                                                           4 4.06 a-c                                                                            4 3.38 a                              8 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 296.9 a-e                                                                           4 1.574 b-f                                                                           4 3.13 b-e                                                                            4 3.13 a-c                            8 + 8 4 0.0 e                                                                               4 0.0 e                                                                               4 274.3 d-e                                                                           4 1.572 b-f                                                                           4 9.81 e-g                                                                            4 0.75 e-g                            16 + 2                                                                               4 0.0 e                                                                               4 0.0 e                                                                               4 323.2 a-b                                                                           4 1.476 e-f                                                                           4 2.81 b-f                                                                            4 3.38 a                              16 + 4                                                                               4 0.0 e                                                                               4 0.0 e                                                                               4 298.3 a-e                                                                           4 1.635 a-e                                                                           4 2.13 c-g                                                                            4 3.13 a-c                            16 + 8                                                                               4 0.0 e                                                                               4 0.0 e                                                                               4 274.6 c-e                                                                           4 1.558 b-f                                                                           4 0.56 f-g                                                                            4 0.56 e-g                            A82810 + Example No. 57                                                        2 + 2 4 0.0 e                                                                               4 0.0 e                                                                               4 296.0 a-e                                                                           4 1.567 b-f                                                                           4 3.50 a-d                                                                            4 3.13 a-c                            2 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 300.3 a-e                                                                           4 1.549 c-f                                                                           4 4.06 a-c                                                                            4 3.06 a-c                            2 + 8 4 6.3 a-e                                                                             4 0.0 e                                                                               4 290.6 a-e                                                                           4 1.614 a-f                                                                           4 0.06 g                                                                              4 0.38 e-g                            4 + 2 4 6.3 a-e                                                                             4 0.0 e                                                                               4 320.4 a-c                                                                           3 1.513 c-f                                                                           4 2.54 b-f                                                                            4 3.06 a-c                            4 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 305.3 a-e                                                                           4 1.538 c-f                                                                           4 1.88 c-g                                                                            4 1.88 c-d                            4 + 8 4 0.0 e                                                                               4 0.0 e                                                                               4 291.1 a-e                                                                           4 1.600 a-f                                                                           4 0.00 g                                                                              4 0.25 e-g                            8 + 2 4 0.0 e                                                                               4 0.0 e                                                                               4 312.3 a-d                                                                           4 1.506 d-f                                                                           4 2.94 b-e                                                                            4 1.50 d-e                            8 + 4 4 6.3 a-e                                                                             4 0.0 e                                                                               4 303.1 a-e                                                                           3 1.553 b-f                                                                           4 1.25 d-g                                                                            4 1.44 d-f                            8 + 8 4 0.0 e                                                                               4 0.0 e                                                                               4 282.1 a-e                                                                           4 1.579 b-f                                                                           4 0.19 g                                                                              4 0.19 f-g                            16 + 2                                                                               4 0.0 e                                                                               4 0.0 e                                                                               4 276.6 b-e                                                                           4 1.616 a-f                                                                           4 0.06 g                                                                              4 0.38 e-g                            16 + 4                                                                               4 6.3 a-e                                                                             4 0.0 e                                                                               4 308.3 a-e                                                                           3 1.526 c-f                                                                           4 1.06 e-g                                                                            4 0.56 e-g                            16 + 8                                                                               4 0.0 e                                                                               4 0.0 e                                                                               4 256.4 e                                                                             4 1.732 a-b                                                                           4 0.00 g                                                                              4 0.00 g                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 32                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                         Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    4 0.0 e                                                                               4 0.0 a                                                                               4 318.6 a                                                                             4 1.467 b-e                                                                           4 1.63 i-j                                                                            4 0.13 g                              IC    4 6.3 a-c                                                                             4 0.0 a                                                                               4 274.0 b-f                                                                           3 1.588 a-e                                                                           4 8.29 a                                                                              4 3.29 a                              A80190 + Example No. 57                                                        2 + 2 4 0.0 e                                                                               4 0.0 a                                                                               4 258.3 f                                                                             4 1.599 a-c                                                                           4 7.88 a-b                                                                            4 2.94 a-c                            2 + 4 4 0.0 e                                                                               4 0.0 a                                                                               4 2.56.2 f                                                                            4 1.651 a                                                                             4 6.31 a-f                                                                            4 3.31 a                              2 + 8 4 0.0 e                                                                               4 0.0 a                                                                               4 269.0 d-f                                                                           4 1.582 a-e                                                                           4 5.13 a-h                                                                            4 2.50 a-d                            4 + 2 4 6.3 a-c                                                                             4 0.0 a                                                                               4 272.1 c-f                                                                           3 1.611 a-b                                                                           4 7.31 a-c                                                                            4 3.56 a                              4 + 4 4 0.0 e                                                                               4 0.0 a                                                                               4 292.7 a-f                                                                           4 1.528 a-e                                                                           4 6.25 a-f                                                                            4 3.19 a-b                            4 + 8 4 0.0 e                                                                               4 0.0 a                                                                               4 280.0 b-f                                                                           4 1.578 a-e                                                                           4 4.50 c-i                                                                            4 2.06 b-d                            8 + 2 4 0.0 e                                                                               4 0.0 a                                                                               4 265.8 3-f                                                                           4 1.577 a-e                                                                           4 7.44 a-c                                                                            4 3.00 a-c                            8 + 4 4 0.0 e                                                                               4 0.0 a                                                                               4 275.5 b-f                                                                           4 1.542 a-e                                                                           4 6.13 a-f                                                                            4 2.88 a-c                            8 + 8 4 0.0 e                                                                               4 0.0 a                                                                               4 274.7 b-f                                                                           4 1.571 a-e                                                                           4 3.69 d-j                                                                            4 0.94 e- g                           16 + 2                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 285.9 a-f                                                                           4 1.560 a-e                                                                           4 7.06 a-c                                                                            4 3.00 a-c                            16 + 4                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 296.9 a-e                                                                           4 1.512 a-e                                                                           4 5.44 a-g                                                                            4 2.06 b-d                            16 + 8                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 286.8 a-f                                                                           4 1.566 a-e                                                                           4 3.50 e-j                                                                            4 0.88 e-g                            A82810 + Example No. 57                                                        2 + 2 4 0.0 e                                                                               4 0.0 a                                                                               4 289.0 a-f                                                                           4 1.573 a-e                                                                           4 7.13 a-c                                                                            4 3.38 a                              2 + 4 4 0.0 e                                                                               4 0.0 a                                                                               4 301.3 a-e                                                                           4 1.505 a-e                                                                           4 6.50 a-e                                                                            4 3.25 a                              2 + 8 4 0.0 e                                                                               4 0.0 a                                                                               4 285.5 a-f                                                                           4 1.595 a-e                                                                           4 3.19 f-j                                                                            4 0.88 e-g                            4 + 2 4 0.0 e                                                                               4 0.0 a                                                                               4 306.3 a-d                                                                           4 1.490 a-e                                                                           4 6.81 a-d                                                                            4 3.31 a                              4 + 4 4 0.0 e                                                                               4 0.0 a                                                                               4 309.1 a-c                                                                           4 1.455 c-e                                                                           4 4.81 c-e                                                                            4 1.63 d-f                            4 + 8 4 0.0 e                                                                               4 0.0 a                                                                               4 287.3 a-f                                                                           4 1.488 a-f                                                                           4 2.88 g-j                                                                            4 0.63 f-g                            8 + 2 4 6.3 a-c                                                                             4 0.0 a                                                                               4 311.7 a-b                                                                           3 1.450 d-e                                                                           4 6.04 a-f                                                                            4 1.88 c-e                            8 + 4 4 0.0 e                                                                               4 0.0 a                                                                               4 305.3 a-d                                                                           4 1.455 e                                                                             4 3.74 d-j                                                                            4 0.81 e-g                            8 + 8 4 0.0 e                                                                               4 0.0 a                                                                               4 281.6 a-f                                                                           4 1.513 a-e                                                                           4 1.56 i-j                                                                            4 0.56 f-g                            16 + 2                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 290.0 a-f                                                                           4 1.535 a-e                                                                           4 3.81 d-j                                                                            4 0.56 f-g                            16 + 4                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 282.4 a-f                                                                           4 1.568 a-e                                                                           4 2.06 h-j                                                                            4 0.50 f-g                            16 + 8                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 265.6 e-f                                                                           4 1.596 a-d                                                                           4 0.75 j                                                                              4 0.00 g                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 33                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                         Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    4 0.0 e                                                                               4 0.0 a                                                                               4 341.1 a                                                                             4 1.395 c-e                                                                           4 2.00 d-f                                                                            4 0.06 f                              IC    4 0.0 e                                                                               4 0.0 a                                                                               4 314.8 a-d                                                                           4 1.439 a-e                                                                           4 6.44 a                                                                              4 2.44 a-b                            A80190                                                                         10    4 0.0 e                                                                               4 0.0 a                                                                               4 325.6 a-c                                                                           4 1.429 a-e                                                                           4 5.88 a-b                                                                            4 2.69 a                              20    4 0.0 e                                                                               4 0.0 a                                                                               4 310.7 a-e                                                                           4 1.377 e                                                                             4 5.69 a-b                                                                            4 2.44 a-b                            30    4 0.0 e                                                                               4 0.0 a                                                                               4 294.6 b-e                                                                           4 1.430 a-e                                                                           4 5.56 a-c                                                                            4 2.31 a-b                            40    4 0.0 e                                                                               4 0.0 a                                                                               4 308.6 a-e                                                                           4 1.436 a-e                                                                           4 4.69 a-f                                                                            4 2.06 a-b                            Example No. 57                                                                 2     4 0.0 e                                                                               4 0.0 a                                                                               4 296.5 a-e                                                                           4 1.466 a-e                                                                           4 5.31 a-d                                                                            4 2.19 a-b                            4     4 0.0 e                                                                               4 0.0 a                                                                               4 283.2 b-e                                                                           4 1.500 a-e                                                                           4 5.81 a-b                                                                            4 2.19 a-b                            6     4 0.0 e                                                                               4 0.0 a                                                                               4 290.4 b-e                                                                           4 1.470 a-e                                                                           4 6.50 a                                                                              4 2.31 a-b                            8     4 0.0 e                                                                               4 0.0 a                                                                               4 267.3 e                                                                             4 1.593 a                                                                             4 3.88 a-f                                                                            4 1.25 b-f                            A80190 + Example No. 57                                                        10 + 2                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 314.7 a-d                                                                           4 1.437 a-e                                                                           4  5.44 a-c                                                                           4 2.19 a-b                            10 + 4                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 296.7 a-e                                                                           4 1.481 a-e                                                                           4 5.00 a-e                                                                            4 2.13 a-b                            10 + 6                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 295.1 e-f                                                                           4 1.550 a-c                                                                           4 4.75 a-f                                                                            4 2.13 a-b                            10 + 8                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 280.6 c-e                                                                           4 1,566 a-b                                                                           4 2.69 b-f                                                                            4 9,56 c-f                            20 + 2                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 305.7 a-e                                                                           4 1.408 b-e                                                                           4 4.81 a-f                                                                            4 2.19 a-b                            20 + 4                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 304.9 a-e                                                                           4 1.465 a-e                                                                           4 3.50 a-f                                                                            4 1.44 a-e                            20 + 6                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 298.7 a-e                                                                           4 1.452 a-e                                                                           4 4.44 a-f                                                                            4 1.50 a-d                            20 + 8                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 288.0 b-e                                                                           4 1.515 a-e                                                                           4 2.56 b-f                                                                            4 0.19 f                              30 + 2                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 308.7 a-e                                                                           4 1.414 a-e                                                                           4 4.44 a-f                                                                            4 1.69 a-c                            30 + 4                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 297.7 a-e                                                                           4 1.456 a-e                                                                           4 4.06 a-f                                                                            4 0.75 c-f                            30 + 6                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 296.6 a-e                                                                           4 1.484 a-e                                                                           4 2.19 c-f                                                                            4 0.44 d-f                            30 + 8                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 280.2 d-e                                                                           4 1.494 a-e                                                                           4 1.50 f                                                                              4 0.13 f                              40 + 2                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 327.7 a-b                                                                           4 1.377 e                                                                             4 4.50 a-f                                                                            4 0.81 c-f                            40 + 4                                                                               4 6.3 a                                                                               4 0.0 a                                                                               4 302.8 a-e                                                                           3 1.450 a-e                                                                           4 3.60 a-f                                                                            4 0.69 c-f                            40 + 6                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 301.6 a-e                                                                           4 1.537 a-d                                                                           4 1.88 e-f                                                                            4 0.31 e-f                            40 + 8                                                                               4 0.0 e                                                                               4 0.0 a                                                                               4 294.0 b-e                                                                           4 1.533 a-e                                                                           4 1.63 e-f                                                                            4 0.25 f                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 34                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                     Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    4 0.0 a                                                                               4 0.0 a                                                                               4 326.7 a                                                                             4 1.352 d                                                                             4 0.00 f                                                                              4 0.00 e                              IC    4 0.0 a                                                                               4 0.0 a                                                                               4 279.3 b-e                                                                           3 1.613 a-c                                                                           4 5.88 a                                                                              4 3.50 a-b                            A80190                                                                         20    4 0.0 a                                                                               4 0.0 a                                                                               4 299.3 a-e                                                                           4 1.549 a-c                                                                           4 3.75 c                                                                              4 3.50 a-b                            40    4 0.0 a                                                                               4 0.0 a                                                                               4 317.5 a-b                                                                           4 1.447 b-d                                                                           4 0.94 e-f                                                                            4 1.13 d                              60    4 0.0 a                                                                               4 0.0 a                                                                               4 287.7 a-e                                                                           3 1.547 a-c                                                                           4 0.35 f                                                                              4 0.58 d-e                            Example No. 57                                                                 2     4 0.0 a                                                                               4 0.0 a                                                                               4 266.2 c-e                                                                           4 1.625 a-b                                                                           4 5.75 a                                                                              4 3.63 a                              3     4 0.0 a                                                                               4 0.0 a                                                                               4 274.2 b-e                                                                           4 1.635 a                                                                             4 5.19 a-b                                                                            4 3.44 a-b                            4     4 0.0 a                                                                               4 6.3 a                                                                               4 262.1 d-e                                                                           3 1.617 a-c                                                                           4 5.56 a                                                                              4 3.19 a-b                            5     4 0.0 a                                                                               4 0.0 a                                                                               4 267.3 c-e                                                                           4 1.579 a-c                                                                           4 4.63 b                                                                              4 3.50 a-b                            A80190 + Example No. 57                                                        20 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 295.5 a-e                                                                           4 1.507 a-d                                                                           4 219 d                                                                               4 3.56 a-b                            20 + 3                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 294.2 a-e                                                                           3 1.493 a-d                                                                           4 1.50 d-e                                                                            4 2.65 b-c                            20 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 312.6 a-c                                                                           4 1.450 b-d                                                                           4 1.19 e-f                                                                            4 2.06 c                              20 + 5                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 297.3 a-e                                                                           4 1.472 a-d                                                                           4 0.38 f                                                                              4 1.19 d                              40 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 311.5 a-c                                                                           4 1.432 c-d                                                                           4 0.19 f                                                                              4 0.69 d-e                            40 + 3                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 306.4 a-d                                                                           4 1.448 b-d                                                                           4 0.63 e-f                                                                            4 0.50 d-e                            40 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 271.3 b-e                                                                           4 1.580 a-c                                                                           4 0.31 f                                                                              4 0.44 d-e                            40 + 5                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 297.4 a-e                                                                           4 1.436 c-d                                                                           4 0.13 f                                                                              4 0.25 d-e                            60 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 279.5 b-e                                                                           2 1.381 c-d                                                                           4 0.00 f                                                                              4 0.13 e                              60 + 3                                                                               4 12.5 a                                                                              4 0.0 a                                                                               4 277.9 b-e                                                                           3 1.555 a-c                                                                           4 0.13 f                                                                              4 0.15 e                              60 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 254.1 e                                                                             4 1.634 a                                                                             4 0.00 f                                                                              4 0.06 e                              60 + 5                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 260.6 d-e                                                                           4 1.590 a-c                                                                           4 0.00 f                                                                              4 0.00 e                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 35                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                         Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    4 0.0 b                                                                               4 0.0 a                                                                               4 332.1 a-c                                                                           4 1.482 a-c                                                                           4 0.81 e                                                                              4 0.00 f                              IC    4 0.0 b                                                                               4 0.0 a                                                                               4 308.2 a-d                                                                           3 1.523 a-c                                                                           4 7.13 a                                                                              4 2.56 a-b                            A80190                                                                         20    4 0.0 b                                                                               4 0.0 a                                                                               4 312.4 a-d                                                                           4 1.544 a-c                                                                           4 5.81 a-b                                                                            4 2.13 b-c                            40    4 0.0 b                                                                               4 0.0 a                                                                               4 338.1 a-b                                                                           4 1.405 b-c                                                                           4 4.06 b-d                                                                            4 1.19 d-e                            60    4 0.0 b                                                                               4 0.0 a                                                                               4 277.1 d                                                                             4 1.655 a                                                                             4 1.94 d-e                                                                            4 0.63 e-f                            Example No. 57                                                                 2     4 18.8 a                                                                              4 12.5 a                                                                              4 282.4 d                                                                             2 1.609 a-c                                                                           4 6.65 a-b                                                                            4 3.27 a                              3     4 6.3 a-b                                                                             4 6.3 a                                                                               4 275.5 d                                                                             3 1.526 a-c                                                                           4 6.56 a-b                                                                            4 2.75 a-b                            4     4 0.0 b                                                                               4 0.0 a                                                                               4 285.3 d                                                                             4 1.554 a-c                                                                           4 5.81 a-b                                                                            4 2.38 b                              5     4 0.0 b                                                                               4 0.0 a                                                                               4 296.8 b-d                                                                           4 1.542 a-c                                                                           4 5.69 a-b                                                                            4 2.06 b-d                            A80190 + Example No. 57                                                        20 + 2                                                                               4 6.3 a-b                                                                             4 0.0 a                                                                               4 314.7 a-d                                                                           3 1.523 a-c                                                                           4 5.06 a-c                                                                            4 1.92 b-d                            20 + 3                                                                               4 0.0 b                                                                               4 0.0 a                                                                               4 312.2 a- d                                                                          4 1.501 a-d                                                                           4 4.94 a-c                                                                            4 1.81 b-d                            20 + 4                                                                               4 0.0 b                                                                               4 0.0 a                                                                               4 318.4 a-d                                                                           4 1.493 a-c                                                                           4 4.25 a-d                                                                            4 1.25 c-e                            20 + 5                                                                               4 0.0 b                                                                               4 0.0 a                                                                               4 309.1 a-d                                                                           4 1.493 a-c                                                                           4 2.88 c-e                                                                            4 0.63 e-f                            40 + 2                                                                               4 0.0 b                                                                               4 0.0 a                                                                               4 346.9 a                                                                             4 1.381 c                                                                             4 2.19 d-e                                                                            4 0.63 e-f                            40 + 3                                                                               4 0.0 b                                                                               4 0.0 a                                                                               4 313.5 a-d                                                                           4 1.500 a-c                                                                           4 2.06 d-e                                                                            4 0.31 e-f                            40 + 4                                                                               4 0.0 b                                                                               4 0.0 a                                                                               4 308.3 a-d                                                                           4 1.487 a-c                                                                           4 2.00 d-e                                                                            4 0.44 e-f                            40 + 5                                                                               4 0.0 b                                                                               4 0.0 a                                                                               4 289.5 c-d                                                                           4 1.536 a-c                                                                           4 1.13 e                                                                              4 0.13 f                              60 + 2                                                                               4 6.3 a-b                                                                             4 0.0 a                                                                               4 300.6 b-d                                                                           3 1.612 a-b                                                                           4 1.27 e                                                                              4 0.29 e-f                            60 + 3                                                                               4 0.0 b                                                                               4 0.0 a                                                                               4 296.1 b-d                                                                           4 1.546 a-c                                                                           4 0.56 e                                                                              4 0.25 e-f                            60 + 4                                                                               4 0.0 b                                                                               4 0.0 a                                                                               4 289.3 c-d                                                                           4 1.621 a                                                                             4 0.13 e                                                                              4 0.06 f                              60 + 5                                                                               4 0.0 b                                                                               4 0.0 a                                                                               4 275.6 d                                                                             4 1.624 a                                                                             4 0.75 e                                                                              4 0.06 f                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 36                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                     Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    4 6.3 a                                                                               4 0.0 a                                                                               4 318.4 a                                                                             4 1.358 d                                                                             4 0.00 f                                                                              4 0.00 e                              IC    4 0.0 a                                                                               4 0.0 a                                                                               4 257.7 c-d                                                                           3 1.676 a-b                                                                           4 5.75 a                                                                              4 3.50 a                              Monensin                                                                       20    4 6.3 a                                                                               4 0.0 a                                                                               4 277.0 a-d                                                                           4 1.604 a-c                                                                           4 4.44 a-b                                                                            4 3.21 a-b                            40    4 0.0 a                                                                               4 0.0 a                                                                               4 280.0 a-d                                                                           4 1.550 a-d                                                                           4 3.38 b-c                                                                            4 3.38 a                              60    4 0.0 a                                                                               4 0.0 a                                                                               4 281.8 a-d                                                                           4 1.527 a-d                                                                           4 3.25 b-c                                                                            4 3.56 a                              80    4 0.0 a                                                                               4 0.0 a                                                                               4 306.3 a-b                                                                           4 1.445 c-d                                                                           4 2.25 c-e                                                                            4 3.19 a-b                            Example No. 57                                                                 2     4 0.0 a                                                                               4 0.0 a                                                                               4 249.3 d                                                                             4 1.695 a                                                                             4 5.88 a                                                                              4 3.38 a                              4     4 0.0 a                                                                               4 0.0 a                                                                               4 270.2 b-d                                                                           4 1.594 a-c                                                                           4 5.31 a                                                                              4 2.81 a-c                            6     4 0.0 a                                                                               4 0.0 a                                                                               4 263.5 b-d                                                                           4 1.588 a-c                                                                           4 4.44 a-b                                                                            4 3.13 a-b                            Monesin + Example No. 57                                                       20 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 289.0 a-d                                                                           4 1.497 a-d                                                                           4 2.81 b-d                                                                            4 3.44 a                              20 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 291.9 a-d                                                                           4 1.450 c-d                                                                           4 3.25 b-c                                                                            4 3.13 a-b                            20 + 6                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 277.9 a-d                                                                           4 1.556 a-d                                                                           4 2.06 c-e                                                                            4 1.81 c-d                            40 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 289.8 a-d                                                                           4 1.492 a-d                                                                           4 2.94 b-d                                                                            4 3.19 a-b                            40 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 298.7 a-c                                                                           4 1.463 b-d                                                                           4 2.31 c-e                                                                            4 2.40 a-d                            40 + 6                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 285.0 a-d                                                                           4 1.515 a-d                                                                           4 1.19 d-f                                                                            4 2.38 a-d                            60 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 304.9 a-c                                                                           4 1.425 c-d                                                                           4 2.19 c-e                                                                            4 2,84 a-c                            60 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 289.7 a-d                                                                           4 1.470 b-d                                                                           4 2.13 c-e                                                                            4 2.69 a-c                            60 + 6                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 275.0 a-d                                                                           4 1.565 a-d                                                                           4 0.56 e-f                                                                            4 1.88 b-d                            80 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 293.5 a-d                                                                           4 1.470 b-d                                                                           4 1.88 c-e                                                                            4 3.50 a                              80 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 301.5 a-c                                                                           4 1.487 a-d                                                                           4 1.06 d-f                                                                            4 2.75 a-c                            80 + 6                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 286.9 a-d                                                                           4 1.460 b-d                                                                           4 0.63 e-f                                                                            4 1.50 d                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 37                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                         Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    4 0.0 b                                                                               4 0.0 b                                                                               4 322.4 a                                                                             4 1.473 g                                                                             4 0.00 e                                                                              4 0.00 b                              IC    4 43.8 a                                                                              4 43.8 a                                                                              4 145.9 g-h                                                                           4 2.438 b-c                                                                           4 8.06 a                                                                              4 3.94 a                              Monensin                                                                       20    4 37.5 a-b                                                                            4 37.5 a-b                                                                            4 165.9 f-h                                                                           4 2.364 b-d                                                                           4 8.13 a                                                                              4 3.81 a                              40    4 25.0 a-b                                                                            4 25.0 a-b                                                                            4 177.1 e-h                                                                           4 2.306 b-e                                                                           4 8.19 a                                                                              4 3.75 a                              60    4 6.3 a-b                                                                             4 6.3 a-b                                                                             4 180.6 e-h                                                                           4 2.252 b-f                                                                           4 7.63 a                                                                              4 3.63 a                              80    4 18.8 a-b                                                                            4 18.8 a-b                                                                            4 162.1 f-h                                                                           4 2.126 b-f                                                                           4 7.56 a                                                                              4 3.18 a                              Example No. 57                                                                 2     4 43.8 a                                                                              4 43.8 a                                                                              4 141.8 g-h                                                                           4 2.623 a-b                                                                           4 7.69 a                                                                              4 3.81 a                              4     4 37.5 a-b                                                                            4 37.5 a-b                                                                            4 172.8 f-h                                                                           4 2.310 b-e                                                                           4 6.44 a-d                                                                            4 3.88 a                              6     4 12.5 a-b                                                                            4 12.5 a-b                                                                            4 179.1 e-h                                                                           4 2.169 b-f                                                                           4 7.31 a-b                                                                            4 3.69 a                              Monesin + Example No. 57                                                       20 + 2                                                                               4 12.5 a-b                                                                            4 12.5 a-b                                                                            4 133.7 h                                                                             4 2.892 a                                                                             4 7.94 a                                                                              4 3.94 a                              20 + 4                                                                               4 18.8 a-b                                                                            4 18.8 a-b                                                                            4 194.0 d-h                                                                           4 2.128 b-f                                                                           4 6.94 a-c                                                                            4 3.94 a                              20 + 6                                                                               4 12.5 a-b                                                                            4 12.5 a-b                                                                            4 221.9 b-f                                                                           4 1.715 c-g                                                                           4 6.81 a-c                                                                            4 3.63 a                              40 + 2                                                                               4 6.3 a-b                                                                             4 6.3 a-b                                                                             4 180.0 e-h                                                                           4 2.182 b-f                                                                           4 7.94 a                                                                              4 3.75 a                              40 + 4                                                                               4 6.3 a-b                                                                             4 6.3 a-b                                                                             4 205.5 c-g                                                                           4 2.099 b-f                                                                           4 7.69 a                                                                              4 4.00 a                              40 + 6                                                                               4 6.3 a-b                                                                             4 6.3 a-b                                                                             4 247.9 b-d                                                                           4 1.716 d-g                                                                           4 6.25 a-d                                                                            4 3.81 a                              60 + 2                                                                               4 12.5 a-b                                                                            4 12.5 a-b                                                                            4 228.2 b-f                                                                           4 1.815 c-g                                                                           4 7.19 a-b                                                                            4 3.94 a                              60 + 4                                                                               4 12.5 a-b                                                                            4 6.3 a-b                                                                             4 243.8 b-e                                                                           4 1.770 d-g                                                                           4 6.90 a-c                                                                            4 3.75 a                              60 + 6                                                                               4 6.3 a-b                                                                             4 6.3 a-b                                                                             4 266.7 b-c                                                                           4 1.651 e-g                                                                           4 5.06 c-d                                                                            4 3.94 a                              80 + 2                                                                               4 31.3 a-b                                                                            4 31.3 a∝b                                                                     4 209.9 b-g                                                                           4 1.994 b-g                                                                           4 6.94 a-c                                                                            4 3.81 a                              80 + 4                                                                               4 0.0 b                                                                               4 0.0 b                                                                               4 261.1 b-c                                                                           4 1.612 f-g                                                                           4 5.50 b-d                                                                            4 3.81 a                              80 + 6                                                                               4 0.0 b                                                                               4 0.0 b                                                                               4 274.5 b                                                                             4 1.653 e-g                                                                           4 4.94 d                                                                              4 3.69 a                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 38                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E acervulina, E. tenella and E. maxima                                                                           Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    4 0.0 a                                                                               4 0.0 a                                                                               4 321.1 a-b                                                                           4 1.488 b                                                                             4 0.00 b                                                                              4 0.00 c                              IC    4 6.3 a                                                                               4 0.0 a                                                                               4 214.4 c                                                                             4 1.960 a                                                                             4 8.00 a                                                                              4 3.73 a                              A80190                                                                         30    4 0.0 a                                                                               4 0.0 a                                                                               4 334.0 a                                                                             4 1.437 b                                                                             4 0.25 b                                                                              4 0.25 c                              40    4 0.0 a                                                                               4 0.0 a                                                                               4 330.8 a                                                                             4 1.430 b                                                                             4 0.25 b                                                                              4 0.00 c                              50    4 0.0 a                                                                               4 0.0 a                                                                               4 306.1 a-b                                                                           4 1.480 b                                                                             4 0.00 b                                                                              4 0.00 c                              Example No. 57                                                                 2     4 6.3 a                                                                               4 6.3 a                                                                               4 223.5 c                                                                             4 1.852 a                                                                             4 8.06 a                                                                              4 3.50 a-b                            3     4 6.3 a                                                                               4 0.0 a                                                                               4 218.0 c                                                                             4 1.897 a                                                                             4 8.44 a                                                                              4 3.08 b                              4     4 0.0 a                                                                               4 0.0 a                                                                               4 228.1 c                                                                             4 1.892 a                                                                             4 8.06 a                                                                              4 3.69 a                              A80190 + Example No. 57                                                        30 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 324.7 a-b                                                                           4 1.407 b                                                                             4 0.00 b                                                                              4 0.25 c                              30 + 3                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 315.3 a-b                                                                           4 1.459 b                                                                             4 0.00 b                                                                              4 0.13 c                              30 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 317.1 a-b                                                                           4 1.424 b                                                                             4 0.00 b                                                                              4 0.00 c                              40 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 329.2 a                                                                             4 1.414 b                                                                             4 0.00 b                                                                              4 0.00 c                              40 + 3                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 292.5 a-b                                                                           4 1.503 b                                                                             4 0.00 b                                                                              4 0.00 c                              40 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 285.1 b                                                                             4 1.562 b                                                                             4 0.00 b                                                                              4 0.00 c                              50 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 304.3 a-b                                                                           4 1.497 b                                                                             4 0.00 b                                                                              4 0.00 c                              50 + 3                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 304.4 a-b                                                                           4 1.487 b                                                                             4 0.00 b                                                                              4 0.00 c                              50 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 303.6 a-b                                                                           4 1.522 b                                                                             4 0.00 b                                                                              4 0.00 c                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 39                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina, E. maxima and E. tenella                                                                                    Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    4 0.0  a  4 0.0  b  4 316.7                                                                              a  4 1.414                                                                              b  4 0.00                                                                               d  4 0.00                                                                               f                   IC                                                                              0    4 25.0 a  4 25.0 a  4 169.3                                                                              c  4 2.188                                                                              a  4 8.75                                                                               a  4 3.81                                                                               a                   A80190                                                                         30    4 0.0  a  4 0.0  b  4 256.0                                                                              b  4 1.586                                                                              b  4 7.63                                                                               a  4 3.69                                                                               a                   40    4 0.0  a  4 0.0  b  4 274.8                                                                              a-b                                                                               4 1.572                                                                              b  4 5.31                                                                               b  4 2.75                                                                               a-d                 50    4 6.3  a  4 0.0  b  4 290.1                                                                              a-b                                                                               4 1.487                                                                              b  4 2.90                                                                               b-d                                                                               4 2.17                                                                               b-e                 Example No. 57                                                                  2    4 12.5 a  4 12.5 a-b                                                                               4 185.7                                                                              c  4 2.039                                                                              a  4 8.50                                                                               a  4 3.50                                                                               a-b                  3    4 18.8 a  4 12.5 a-b                                                                               4 189.1                                                                              c  4 2.091                                                                              a  4 8.65                                                                               a  4 3.75                                                                               a                    4    4 18.8 a  4 18.8 a-b                                                                               4 161.3                                                                              c  4 2.222                                                                              a  4 8.25                                                                               a  4 3.81                                                                               a                   A80190 + Example No. 57                                                        30 + 2                                                                               4 0.0  a  4 0.0  b  4 269.6                                                                              a-b                                                                               4 1.597                                                                              b  4 5.25                                                                               b  4 3.06                                                                               a-c                 30 + 3                                                                               4 0.0  a  4 0.0  b  4 295.6                                                                              a-b                                                                               4 1.477                                                                              b  4 3.38                                                                               b-c                                                                               4 2.81                                                                               a-d                 30 + 4                                                                               4 0.0  a  4 0.0  b  4 294.5                                                                              a-b                                                                               4 1.481                                                                              b  4 1.19                                                                               c-d                                                                               4 1.75                                                                               c-e                 40 + 2                                                                               4 0.0  a  4 0.0  b  4 269.1                                                                              a-b                                                                               4 1.647                                                                              b  4 3.50                                                                               b-c                                                                               4 2.50                                                                               a-d                 40 + 3                                                                               4 12.5 a  4 6.3  a-b                                                                               4 290.7                                                                              a-b                                                                               4 1.489                                                                              b  4 1.60                                                                               c-d                                                                               4 1.56                                                                               d-e                 40 + 4                                                                               4 0.0  a  4 0.0  b  4 300.0                                                                              a-b                                                                               4 1.493                                                                              b  4 0.00                                                                               d  4 1.44                                                                               d-e                 50 + 2                                                                               4 0.0  a  4 0.0  b  4 266.7                                                                              a-b                                                                               4 1.584                                                                              b  4 0.19                                                                               d  4 0.88                                                                               e-f                 50 + 3                                                                               4 0.0  a  4 0.0  b  4 268.7                                                                              a-b                                                                               4 1.608                                                                              b  4 0.25                                                                               d  4 0.75                                                                               e-f                 50 + 4                                                                               4 0.0  a  4 0.0  b  4 273.4                                                                              a-b                                                                               4 1.556                                                                              b  4 0.00                                                                               d  4 0.88                                                                               e-f                 __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 40                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  a  3 0.0  a  3 333.5                                                                              a  3 1.400                                                                              d  3 0.00                                                                               c  3 0.00                                                                               g                   IC                                                                             0     3 0.0  a  3 0.0  a  3 235.5                                                                              e-f                                                                               3 1.747                                                                              c  3 8.58                                                                               a  3 3.33                                                                               a                   A204                                                                           2     3 0.0  a  3 0.0  a  3 247.8                                                                              d-e                                                                               3 1.670                                                                              c  3 4.33                                                                               b  3 3.33                                                                               a                   4     3 0.0  a  3 0.0  a  3 278.9                                                                              b-d                                                                               3 1.680                                                                              c  3 3.83                                                                               b  3 3.33                                                                               a                   8     3 0.0  a  3 0.0  a  3 312.7                                                                              a-b                                                                               3 1.487                                                                              c-d                                                                               3 0.17                                                                               c  3 3.00                                                                               a                   Example No. 39                                                                 2     3 0.0  a  3 0.0  a  3 269.0                                                                              c-d                                                                               3 1.653                                                                              c-d                                                                               3 0.33                                                                               c  3 3.50                                                                               a                   4     3 8.3  a  3 0.0  a  3 271.7                                                                              b-d                                                                               2 1.612                                                                              c-d                                                                               3 0.08                                                                               c  3 1.89                                                                               b-c                 8     3 0.0  a  3 0.0  a  3 207.7                                                                              f-g                                                                               3 1.936                                                                              b  3 0.00                                                                               c  3 0.92                                                                               d-f                 A204 + Example No. 39                                                          2 + 2 3 0.0  a  3 0.0  a  3 300.6                                                                              a-c                                                                               3 1.554                                                                              c-d                                                                               3 0.00                                                                               c  3 3.17                                                                               a                   2 +  4                                                                               3 0.0  a  3 0.0  a  3 280.2                                                                              b-d                                                                               3 1.592                                                                              c-d                                                                               3 0.00                                                                               c  3 1.50                                                                               c-d                 2 + 8 3 0.0  a  3 0.0  a  3 205.4                                                                              f-g                                                                               3 2.008                                                                              a-b                                                                               3 0.00                                                                               c  3 0.67                                                                               e-g                 4 + 2 3 0.0  a  3 0.0  a  3 286.3                                                                              b-d                                                                               3 1.553                                                                              c-d                                                                               3 0.00                                                                               c  3 2.17                                                                               b                   4 + 4 3 0.0  a  3 0.0  a  3 279.3                                                                              b-d                                                                               3 1.573                                                                              c-d                                                                               3 0.00                                                                               c  3 1.17                                                                               d-e                 4 + 8 3 0.0  a  3 0.0  a  3 195.0                                                                              g  3 1.984                                                                              a-b                                                                               3 0.00                                                                               c  3 0.17                                                                               f-g                 8 + 2 3 0.0  a  3 0.0  a  3 308.8                                                                              a-c                                                                               3 1.491                                                                              c-d                                                                               3 0.00                                                                               c  3 0.67                                                                               e-g                 8 + 4 3 0.0  a  3 0.0  a  3 292.3                                                                              b-c                                                                               3 1.596                                                                              c-d                                                                               3 0.00                                                                               c  3 0.33                                                                               f-g                 8 + 8 3 8.3  a  3 0.0  a  3 199.3                                                                              g  2 2.187                                                                              a  3 0.00                                                                               c  3 0.00                                                                               g                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 41                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  a  3 0.0  a  3 308.8                                                                              a  3 1.485                                                                              b  3 0.00                                                                               c  3 0.00                                                                               b                   IC                                                                             0     3 0.0  a  3 0.0  a  3 247.1                                                                              c-e                                                                               3 1.722                                                                              a-b                                                                               3 5.25                                                                               a  3 3.42                                                                               a                   A82810                                                                         1     3 0.0  a  3 0.0  a  3 238.1                                                                              c-e                                                                               3 1.797                                                                              a-b                                                                               3 2.75                                                                               b  3 3.17                                                                               a                   3     3 0.0  a  3 0.0  a  3 295.2                                                                              a-b                                                                               3 1.544                                                                              a-b                                                                               3 1.50                                                                               c  3 2.67                                                                               a                   5     3 8.3  a  3 0.0  a  3 301.8                                                                              a  2 1.466                                                                              b  3 0.17                                                                               c  3 0.42                                                                               b                   Example No. 39                                                                 2     3 0.0  a  3 0.0  a  3 235.3                                                                              c-e                                                                               3 1.789                                                                              a-b                                                                               3 1.25                                                                               c  3 3.42                                                                               a                   4     3 0.0  a  3 0.0  a  3 246.0                                                                              c-e                                                                               3 1.766                                                                              a-b                                                                               3 0.00                                                                               c  3 2.58                                                                               a                   8     3 16.7 a  3 0.0  a  3 219.3                                                                              d-e                                                                               2 1.875                                                                              a  3 0.00                                                                               c  3 0.83                                                                               b                   A82810 + Example No. 39                                                        1 + 2 3 0.0  a  3 0.0  a  3 290.9                                                                              a-b                                                                               3 1.499                                                                              b  3 0.33                                                                               c  3 2.75                                                                               a                   1 + 4 3 0.0  a  3 0.0  a  3 253.3                                                                              b-e                                                                               3 1.689                                                                              a-b                                                                               3 0.00                                                                               c  3 0.83                                                                               b                   1 + 8 3 0.0  a  3 0.0  a  3 221.4                                                                              d-e                                                                               3 1.902                                                                              a  3 0.00                                                                               c  3 0.00                                                                               b                   3 + 2 3 0.0  a  3 0.0  a  3 265.9                                                                              a-d                                                                               3 1.673                                                                              a-b                                                                               3 0.08                                                                               c  3 1.17                                                                               b                   3 + 4 3 25.0 a  3 0.0  a  3 269.3                                                                              a-c                                                                               1 1.537                                                                              a-b                                                                               3 0.00                                                                               c  3 0.42                                                                               b                   3 + 8 3 16.7 a  3 0.0  a  3 209.0                                                                              e  1 1.829                                                                              a-b                                                                               3 0.00                                                                               c  3 0.00                                                                               b                   5 + 2 3 0.0  a  3 0.0  a  3 292.1                                                                              a-b                                                                               3 1.551                                                                              a-b                                                                               3 0.00                                                                               c  3 0.33                                                                               b                   5 + 4 3 8.3  a  3 0.0  a  3 277.1                                                                              a-c                                                                               2 1.620                                                                              a-b                                                                               3 0.00                                                                               c  3 0.08                                                                               b                   5 + 8 3 0.0  a  3 0.0  a  3 230.9                                                                              c-e                                                                               3 1.790                                                                              a-b                                                                               3 0.00                                                                               c  3 0.00                                                                               b                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 42                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    3 0.0  a  3 0.0  a  3 261.9                                                                              a-b                                                                               3 1.467                                                                              b  3 0.00                                                                               b  3 0.00                                                                               c                   IC                                                                              0    3 16.7 a  3 0.0  a  3 227.8                                                                              a-c                                                                               1 1.735                                                                              a-b                                                                               3 4.50                                                                               a  3 2.67                                                                               a                    A82810                                                                         1    3 0.0  a  3 0.0  a  3 233.8                                                                              a-c                                                                               3 1.628                                                                              a-b                                                                               3 5.67                                                                               a  3 3.00                                                                               a                    3    3 0.0  a  3 0.0  a  3 270.5                                                                              a  3 1.507                                                                              b  3 1.08                                                                               b  3 1.83                                                                               a-b                  5    3 16.7 a  3 0.0  a  3 255.7                                                                              a-b                                                                               2 1.541                                                                              a-b                                                                               3 0.42                                                                               b  3 0.92                                                                               b-c                 Example No. 57                                                                  3    3 0.0  a  3 0.0  a  3 200.8                                                                              b-c                                                                               3 1.774                                                                              a-b                                                                               3 4.75                                                                               a  3 3.08                                                                               a                    6    3 0.0  a  3 0.0  a  3 218.5                                                                              a-c                                                                               3 1.730                                                                              a-b                                                                               3 1.00                                                                               b  3 2.50                                                                               a                   12    3 0.0  a  3 0.0  a  3 203.0                                                                              a-c                                                                               3 1.783                                                                              a-b                                                                               3 0.00                                                                               b  3 1.17                                                                               b-c                 A82810 + Example No. 57                                                         1 + 3                                                                               3 8.3  a  3 8.3  a  3 256.1                                                                              a-b                                                                               2 1.559                                                                              a-b                                                                               3  2.33                                                                              b  3 2.67                                                                               a                    1 + 6                                                                               3 0.0  a  3 0.0  a  3 255.8                                                                              a-b                                                                               3 1.561                                                                              a-b                                                                               3 0.25                                                                               b  3 1.17                                                                               b-c                  1 + 12                                                                              3 33.3 a  3 0.0  a  3 178.8                                                                              c  1 2.051                                                                              a  3 0.00                                                                               b  3 0.17                                                                               c                    3 + 3                                                                               3 0.0  a  3 0.0  a  3 261.0                                                                              a-b                                                                               3 1.524                                                                              a-b                                                                               3 0.25                                                                               b  3 1.00                                                                               b-c                  3 + 6                                                                               3 0.0  a  3 0.0  a  3 231.2                                                                              a-c                                                                               3 1.646                                                                              a-b                                                                               3 0.00                                                                               b  3 0.42                                                                               b-c                  3 + 12                                                                              3 0.0  a  3 0.0  a  3 217.3                                                                              a-c                                                                               3 1.716                                                                              a-b                                                                               3 0.00                                                                               b  3 0.08                                                                               c                    5 + 3                                                                               3 0.0  a  3 0.0  a  3 245.9                                                                              a-b                                                                               3 1.567                                                                              a-b                                                                               3 0.00                                                                               b  3 0.58                                                                               b-c                  5 + 6                                                                               3 16.7 a  3 0.0  a  3 247.6                                                                              a-b                                                                               1 1.513                                                                              a-b                                                                               3 0.00                                                                               b  3 0.11                                                                               c                    5 + 12                                                                              3 0.0  a  3 0.0  a  3 194.6                                                                              b- c                                                                              3 1.889                                                                              a  3 0.00                                                                               b  3 0.08                                                                               c                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 43                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                                   Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    2 0.0  a  2 0.0  b  2 313.8                                                                              a  2 1.548                                                                              c  2 0.00                                                                               c  2 0.00                                                                               d                   IC                                                                              0    3 8.3  a  3 8.3  b  3 168.3                                                                              d  2 2.404                                                                              a  3 8.58                                                                               a  3 3.58                                                                               a                   A82810                                                                          1    3 8.3  a  3 8.3  b  3 188.8                                                                              c-d                                                                               2 2.037                                                                              b  3 8.42                                                                               a  3 3.42                                                                               a                    3    3 8.3  a  3 0.0  b  3 286.9                                                                              a  2 1.588                                                                              c  3 5.78                                                                               b  3 2.25                                                                               b-c                  5    3 8.3  a  3 0.0  b  3 300.6                                                                              a  2 1.505                                                                              c  3 2.75                                                                               c  3 1.14                                                                               d                   Example No. 57                                                                  3    3 33.3 a  3 33.3 a  3 191.8                                                                              c-d                                                                               1 1.873                                                                              b-c                                                                               3 7.50                                                                               a-b                                                                               3 3.42                                                                               a                    6    3 0.0  a  3 0.0  b  3 227.9                                                                              b-c                                                                               3 1.828                                                                              b-c                                                                               3 5.42                                                                               b  3 3.42                                                                               a                   12    3 8.3  a  3 0.0  b  3 253.8                                                                              a-b                                                                               2 1.740                                                                              b-c                                                                               3 0.50                                                                               c  3 1.42                                                                               c-d                 A82810 + Example No. 57                                                         1 + 3                                                                               3 16.7 a  3 8.3  b  3 266.2                                                                              a-b                                                                               1 1.701                                                                              b-c                                                                               3 3.11                                                                               c  3  3.64                                                                              a                    1 + 6                                                                               3 0.0  a  3 0.0  b  3 255.5                                                                              a-b                                                                               3 1.673                                                                              c  3 2.50                                                                               c  3 2.50                                                                               a-b                  1 + 12                                                                              3 8.3  a  3 0.0  b  3 249.4                                                                              a-b                                                                               2 1.776                                                                              b-c                                                                               3 0.00                                                                               c  3 1.06                                                                               d                    3 + 3                                                                               3 0.0  a  3 0.0  b  3 286.6                                                                              a  3 1.537                                                                              c  3 0.92                                                                               c  3 1.50                                                                               c-d                  3 + 6                                                                               3 0.0  a  3 0.0  b  3 284.5                                                                              a  3 1.556                                                                              c  3 0.17                                                                               c  3 0.92                                                                               d                    3 + 12                                                                              3 8.3  a  3 0.0  b  3 263.4                                                                              a-b                                                                               2 1.746                                                                              b-c                                                                               3 0.08                                                                               c  3 0.17                                                                               d                    5 + 3                                                                               3 0.0  a  3 0.0  b  3 310.1                                                                              a  3 1.517                                                                              c  3 0.00                                                                               c  3 0.67                                                                               d                    5 + 6                                                                               3 0.0  a  3 0.0  b  3 289.3                                                                              a  3 1.571                                                                              c  3 0.00                                                                               c  3 0.25                                                                               d                    5 + 12                                                                              3 8.3  a  3 0.0  b  3 292.5                                                                              a  2 1.577                                                                              c  3 0.00                                                                               c  3 0.00                                                                               d                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 44                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina, E. maxima and E. tenella                                                                                    Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    4 0.0  c  4 0.0  b  4 220.8                                                                              a  4 1.466                                                                              c  4 0.00                                                                               d  4 0.00                                                                               d                   IC                                                                              0    4 55.0 b  4 55.0 a  3  74.2                                                                              c           3 3.64                                                                               b  3 3.81                                                                               a                   Example No. 5                                                                  30    4 100.0                                                                               a  4 0.0  b                                                       20    4 95.0 a  4 5.0  b  1  89.0                                                                              c           1 0.00                                                                               d  1 0.00                                                                               d                   10    4 5.0  c  4 0.0  b  4 144.6                                                                              b  3 2.138                                                                              a  4 0.00                                                                               d  4 1.59                                                                               c                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 45                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella, E. acervulina and E. maxima                                                                                    Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    3 0.0  c  3 0.0  a  3 236.7                                                                              a  3 1.551                                                                              b  3 0.00                                                                               c  3 0.00                                                                               b                   IC                                                                              0    3 13.3 c  3 13.3 a  3 160.7                                                                              b  1 1.950                                                                              a  3 3.62                                                                               a  3 2.93                                                                               a                   Example No. 5                                                                  10    3 13.3 c  3 13.3 a  3 153.7                                                                              b  1 2.176                                                                              a  3 0.25                                                                               c  3 2.30                                                                               a                    7.5  3 13.3 c  3 13.3 a  3 164.9                                                                              b  2 2.050                                                                              a  3 0.47                                                                               c  3 1.82                                                                               a                    5    3 26.7 b-c                                                                               3 26.7 a  3 163.5                                                                              b  1 2.177                                                                              a  3 1.51                                                                               b  3 2.78                                                                               a                    2.5  3 20.0 c  3 20.0 a  3 156.3                                                                              b           3 1.92                                                                               b  3 2.33                                                                               a                   Example No. 90                                                                 75    3 100.0                                                                               a  3 0.0  a                                                       50    3 46.7 b  3 0.0  a  3  70.4                                                                              c           3 0.00                                                                               c  3 0.00                                                                               b                   25    3 0.0  c  3 0.0  a  3 172.3                                                                              b  3 1.968                                                                              a  3 0.00                                                                               c  3 0.67                                                                               b                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 46                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella, E. acervulina and E. maxima                                                                                    Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 6.7  a  3 0.0  a  3 296.0                                                                              a  2 1.289                                                                              c  3 0.00                                                                               b  3 0.00                                                                               d                   IC                                                                             0     3 26.7 a  3 26.7 a  3 166.7                                                                              b           3 8.11                                                                               a  3 3.83                                                                               a                   Example No. 94                                                                 5     2 0.0  a  2 0.0  a  2 218.8                                                                              b  2 1.462                                                                              b-c                                                                               2 1.60                                                                               b  2 3.20                                                                               a                   3.5   2 10.0 a  2 10.0 a  2 208.4                                                                              b  1 1.440                                                                              c  2 1.52                                                                               b  2 3.65                                                                               a                   2     2 40.0 a  2 40.0 a  2 165.1                                                                              b           2 7.00                                                                               a  2 3.67                                                                               a                   Example No. 98                                                                 5     2 0.0  a  2 0.0  a  2 220.3                                                                              b  2 1.478                                                                              b-c                                                                               2 0.30                                                                               b  2 2.50                                                                               b                   3.5   2 30.0 a  2 30.0 a  2 232.4                                                                              b  1 1.614                                                                              b-c                                                                               2 1.30                                                                               b  2 3.80                                                                               a                   2     2 20.0 a  2 20.0 a  2 201.0                                                                              b  1 1.491                                                                              b-c                                                                               2 5.67                                                                               a  2 3.47                                                                               a                   Example No. 5                                                                  7.5   2 0.0  a  2 0.0  a  2 210.4                                                                              b  2 1.557                                                                              b-c                                                                               2 0.40                                                                               b  2 2.00                                                                               b                   5     2 0.0  a  2 0.0  a  2 233.2                                                                              b  2 1.440                                                                              c  2 0.30                                                                               b  2 2.60                                                                               b                   2.5   2 10.0 a  2 10.0 a  2 184.8                                                                              b  1 1.779                                                                              a-b                                                                               2 1.70                                                                               b  2 3.65                                                                               a                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 47                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 25.0 a  3 0.0  a  3 318.5                                                                              a  1 1.425                                                                              c  3 0.00                                                                               d  3 0.00                                                                               c                   IC                                                                             0     3 41.7 a  3 33.3 a  3 229.6                                                                              c           3 8.17                                                                               a-b                                                                               3 3.22                                                                               a-b                 A80190                                                                         8     3 16.7 a  3 0.0  a  3 240.8                                                                              b-c                                                                               2 1.591                                                                              b-c                                                                               3 7.50                                                                               b  3 2.83                                                                               a-b                 Example No. 5                                                                  2.5   3 8.3  a  3 8.3  a  3 213.0                                                                              c  2 1.852                                                                              a  3 9.00                                                                               a  3 3.17                                                                               a-b                 5     3 0.0  a  3 0.0  a  3 242.5                                                                              b-c                                                                               3 1.653                                                                              b  3 0.25                                                                               d  3 3.50                                                                               a                   A80190 + Example No. 5                                                         8 + 2.5                                                                              3 0.0  a  3 0.0  a  3 274.3                                                                              a-c                                                                               3 1.488                                                                              c  3 1.58                                                                               c  3 2.92                                                                               a-b                 8 + 5 3 0.0  a  3 0.0  a  3 297.8                                                                              a-b                                                                               3 1.440                                                                              c  3 0.00                                                                               d  3 1.92                                                                               b                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 48                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  a  3 0.0  a  3 321.8                                                                              a  3 1.391                                                                              c  3 0.00                                                                               b  3 0.00                                                                               c                   IC                                                                             0     3 0.0  a  3 0.0  a  3 199.5                                                                              f  3 1.852                                                                              a  3 6.08                                                                               a  3 2.92                                                                               a-b                 A204                                                                           2     3 0.0  a  3 0.0  a  3 252.2                                                                              c-e                                                                               3 1.649                                                                              a-c                                                                               3 4.00                                                                               a  3 3.42                                                                               a                   4     3 0.0  a  3 0.0  a  3 247.8                                                                              d-e                                                                               3 1.686                                                                              a-b                                                                               3 6.50                                                                               a  3 3.08                                                                               a-b                 8     3 0.0  a  3 0.0  a  3 271.0                                                                              c-e                                                                               3 1.489                                                                              b-c                                                                               3 0.92                                                                               b  3 3.58                                                                               a                   Example No. 5                                                                  2     3 0.0  a  3 0.0  a  3 245.8                                                                              d-e                                                                               3 1.652                                                                              a-c                                                                               3 4.17                                                                               a  3 3.08                                                                               a-b                 4     3 0.0  a  3 0.0  a  3 243.8                                                                              d-e                                                                               3 1.676                                                                              a-c                                                                               3 0.25                                                                               b  3 3.17                                                                               a-b                 8     3 0.0  a  3 0.0  a  3 234.3                                                                              d-e                                                                               3 1.671                                                                              a-c                                                                               3 0.08                                                                               b  3 2.33                                                                               a-b                 A204 + Example No. 5                                                           2 + 2 3 8.3  a  3 8.3  a  3 265.2                                                                              c-e                                                                               2 1.576                                                                              a-c                                                                               3 0.83                                                                               b  3 3.25                                                                               a                   2 + 4 3 0.0  a  3 0.0  a  3 276.0                                                                              c-e                                                                               3 1.491                                                                              b-c                                                                               3 0.08                                                                               b  3 3.50                                                                               a                   2 + 8 3 0.0  a  3 0.0  a  3 246.8                                                                              d-e                                                                               3 1.637                                                                              a-c                                                                               3 0.00                                                                               b  3 0.67                                                                               c                   4 + 2 3 8.3  a  3 0.0  a  3 262.4                                                                              c-e                                                                               2 1.574                                                                              a-c                                                                               3 0.00                                                                               b  3 2.81                                                                               a-b                 4 + 4 3 0.0  a  3 0.0  a  3 280.7                                                                              b-d                                                                               3 1.540                                                                              b-c                                                                               3 0.00                                                                               b  3 1.83                                                                               b                   4 + 8 3 8.3  a  3 0.0  a  3 229.7                                                                              e  2 1.683                                                                              a-c                                                                               3 0.00                                                                               b  3 0.53                                                                               c                   8 + 2 3 16.7 a  3 0.0  a  3 312.7                                                                              a-b                                                                               2 1.442                                                                              b-c                                                                               3 0.00                                                                               b  3 2.58                                                                               a-b                 8 + 4 3 0.0  a  3 0.0  a  3 293.3                                                                              a-c                                                                               3 1.496                                                                              b-c                                                                               3 0.00                                                                               b  3 0.92                                                                               c                   8 + 8 3 0.0  a  3 0.0  a  3 246.3                                                                              d-e                                                                               3 1.659                                                                              a-c                                                                               3 0.00                                                                               b  3 0.25                                                                               c                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 49                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    3 8.3  b-c                                                                               3 0.0  a  3 325.5                                                                              a  2 1.359                                                                              c  3 0.00                                                                               c  3 0.00                                                                               c                   IC                                                                              0    3 0.0  c  3 0.0  a  3 257.4                                                                              c  3 1.687                                                                              b  3 6.58                                                                               a  3 3.33                                                                               a                   A82810                                                                           1   3 0.0  c  3 0.0  a  3 262.1                                                                              c  3 1.638                                                                              b-c                                                                               3 6.17                                                                               a  3 3.42                                                                               a                    3    3 0.0  c  3 0.0  a  3 288.0                                                                              a-c                                                                               3 1.506                                                                              b-c                                                                               3 2.75                                                                               b  3 2.92                                                                               a                    5    3 0.0  c  3 0.0  a  3 319.8                                                                              a-b                                                                               3 1.424                                                                              b-c                                                                               3 0.92                                                                               b-c                                                                               3 1.75                                                                               b                   Example No. 113                                                                 6    3 8.3  b-c                                                                               3 0.0  a  3 255.2                                                                              c  2 1.662                                                                              b-c                                                                               3 0.17                                                                               b-c                                                                               3 2.06                                                                               b                   12    3 41.7 b  3 0.0  a  3 179.4                                                                              d           3 0.00                                                                               c  3 0.67                                                                               c                   24    1 75.0 a  1 0.0  a  1  53.8                                                                              f           1 0.00                                                                               c  1 0.00                                                                               c                   A82810 + Example No. 113                                                        1 + 6                                                                               3 0.0  c  3 0.0  a  3 264.0                                                                              c  3 1.641                                                                              b-c                                                                               3 0.00                                                                               c  3 1.00                                                                               c                    1 + 12                                                                              3 25.0 b-c                                                                               3 0.0  a  3 160.4                                                                              d  1 2.182                                                                              a  3 0.00                                                                               c  3 0.11                                                                               c                    3 + 6                                                                               3 0.0  c  3 0.0  a  3 274.2                                                                              b-c                                                                               3 1.580                                                                              b-c                                                                               3 0.00                                                                               c  3 0.17                                                                               c                    3 + 12                                                                              3 8.3  b-c                                                                               3 0.0  a  3 184.2                                                                              d  2 2.160                                                                              a  3 0.00                                                                               c  3 0.00                                                                               c                    5 + 6                                                                               3 0.0  c  3 0.0  a  3 265.5                                                                              c  3 1.640                                                                              b-c                                                                               3 0.00                                                                               c  3 0.08                                                                               c                    5 + 12                                                                              3 33.3 b-c                                                                               3 0.0  a  3 113.1                                                                              e           3 0.00                                                                               c  3 0.00                                                                               c                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 50                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  a  3 0.0  a  3 307.9                                                                              a-b                                                                               3 1.516                                                                              b-c                                                                               3 0.00                                                                               b  3 0.00                                                                               d                   IC                                                                             0     3 0.0  a  3 0.0  a  3 258.3                                                                              b-e                                                                               3 1.670                                                                              a-c                                                                               3 5.00                                                                               a  3 2.92                                                                               a-b                  A82810                                                                        1     3 0.0  a  3 0.0  a  3 250.0                                                                              c-e                                                                               3 1.692                                                                              a-c                                                                               3 3.75                                                                               a  3 2.67                                                                               a-b                 3     3 0.0  a  3 0.0  a  3 285.3                                                                              a-d                                                                               3 1.599                                                                              a-c                                                                               3 1.33                                                                               b  3 2.50                                                                               a-b                 5     3 0.0  a  3 0.0  a  3 313.5                                                                              a  3 1.446                                                                              c  3 0.25                                                                               b  3 0.92                                                                               c-d                 Example No. 113                                                                2     3 0.0  a  3 0.0  a  3 254.3                                                                              b-e                                                                               3 1.714                                                                              a-c                                                                               3 3.92                                                                               a  3 3.33                                                                               a                   4     3 8.3  a  3 0.0  a  3 285.4                                                                              a-d                                                                               2 1.541                                                                              a-c                                                                               3 0.39                                                                               b  3 3.19                                                                               a-b                 8     3 0.0  a  3 0.0  a  3 239.7                                                                              c-e                                                                               3 1.724                                                                              a-b                                                                               3 0.00                                                                               b  3 0.42                                                                               c-d                 A82810 + Example No. 113                                                       1 + 2 3 0.0  a  3 0.0  a  3 289.9                                                                              a-d                                                                               3 1.527                                                                              a-c                                                                               3 0.42                                                                               b   3                                                                               1.83                                                                               b-c                 1 + 4 3 0.0  a  3 0.0  a  3 278.3                                                                              a-e                                                                               3 1.528                                                                              a-c                                                                               3 0.00                                                                               b  3 1.08                                                                               c-d                 1 + 8 3 0.0  a  3 0.0  a  3 236.2                                                                              d-e                                                                               3 1.747                                                                              a-b                                                                               3 0.00                                                                               b  3 0.33                                                                               c-d                 3 + 2 3 0.0  a  3 0.0  a  3 316.3                                                                              a  3 1.473                                                                              b-c                                                                               3 0.00                                                                               b  3 0.83                                                                               c-d                 3 + 4 3 8.3  a  3 0.0  a  3 272.9                                                                              a-e                                                                               2 1.482                                                                              b-c                                                                               3 0.00                                                                               b  3 0.72                                                                               c-d                 3 + 8 3 8.3  a  3 0.0  a  3 224.6                                                                              e  2 1.821                                                                              a  3 0.00                                                                               b  3 0.00                                                                               d                   5 + 2 3 0.0  a  3 0.0  a  3 293.7                                                                              a-c                                                                               3 1.477                                                                              b-c                                                                               3 0.00                                                                               b  3 0.58                                                                               c-d                 5 + 4 3 0.0  a  3 0.0  a  3 274.4                                                                              a-e                                                                               3 1.568                                                                              a-c                                                                               3 0.00                                                                               b  3 0.50                                                                               c-d                 5 + 8 3 0.0  a  3 0.0  a  3 234.9                                                                              d-e                                                                               3 1.722                                                                              a-b                                                                               3 0.00                                                                               b  3 0.00                                                                               d                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 51                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                                   Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  b  3 0.0  b  3 345.9                                                                              a  3 1.375                                                                              c  3 0.00                                                                               d  3 0.00                                                                               e                   IC                                                                             0     3 25.0 a-b                                                                               3 16.7 b  3 245.9                                                                              a           3 7.64                                                                               a  3 3.67                                                                               a                   A82810                                                                         1     3 41.7 a  3 41.7 a  3 259.3                                                                              a           3 8.67                                                                               a  3 3.67                                                                               a                   3     3 8.3  b  3 8.3  b  3 281.8                                                                              a  2 1.482                                                                              b-c                                                                               3 7.00                                                                               a  3 2.58                                                                               b-c                 5     3 0.0  b  3 0.0  b  3 270.3                                                                              a  3 1.554                                                                              b-c                                                                               3 8.25                                                                               a  3 2.42                                                                               c                   Example No. 113                                                                2     3 0.0  b  3 0.0  b  3 190.8                                                                              a  3 1.956                                                                              a  3 7.75                                                                               a  3 3.33                                                                               a-b                 4     3 16.7 b  3 16.7 b  3 232.8                                                                              a  2 1.848                                                                              a-b                                                                               3 4.08                                                                               b  3 3.67                                                                               a                   8     3 0.0  b  3 0.0  b  3 234.1                                                                              a  3 1.786                                                                              a-b                                                                               3 0.67                                                                               d  3 1.00                                                                               d-e                 A82810 + Example No. 113                                                       1 + 2 3 0.0  b  3 0.0  b  3 262.0                                                                              a  3 1.674                                                                              a-c                                                                               3 3.08                                                                               b-c                                                                               3 2.83                                                                               a-c                 1 + 4 3 8.3  b  3 0.0  b  3 281.6                                                                              a  2 1.569                                                                              b-c                                                                               3 2.00                                                                               b-d                                                                               3 2.39                                                                               c                   1 + 8 3 0.0  b  3 0.0  b  3 233.4                                                                              a  3 1.741                                                                              a-b                                                                               3 0.33                                                                               d  3 0.83                                                                               d-e                 3 + 2 3 0.0  b  3 0.0  b  3 313.3                                                                              a  3 1.509                                                                              b-c                                                                               3 1.33                                                                               c-d                                                                               3 1.08                                                                               d                   3 + 4 3 0.0  b  3 0.0  b  3 300.0                                                                              a  3 1.538                                                                              b-c                                                                               3 0.00                                                                               d  3 0.58                                                                               d-e                 3 + 8 3 0.0  b  3 0.0  b  3 251.7                                                                              a  3 1.733                                                                              a-b                                                                               3 0.00                                                                               d  3 0.08                                                                               e                   5 + 2 3 0.0  b  3 0.0  b  3 303.4                                                                              a  3 1.478                                                                              b-c                                                                               3 0.00                                                                               d  3 0.25                                                                               d-e                 5 + 4 3 0.0  b  3 0.0  b  3 295.4                                                                              a  3 1.541                                                                              b-c                                                                               3 0.00                                                                               d  3 0.17                                                                               d-e                 5 + 8 3 0.0  b  3 0.0  b  3 279.8                                                                              a  3 1.664                                                                              a-c                                                                               3 0.00                                                                               d  3 0.00                                                                               e                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 52                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  a  3 0.0  a  3 330.2                                                                              a  3 1.346                                                                              d  3 0.00                                                                               c  3 0.00                                                                               c                   IC                                                                             0     3 0.0  a  3 0.0  a  3 240.8                                                                              c-d                                                                               3 1.682                                                                              b-d                                                                               3 7.92                                                                               a  3 3.58                                                                               a                   A204                                                                           2     3 8.3  a  3 8.3  a  3 247.4                                                                              c-d                                                                               2 1.695                                                                              b-d                                                                               3 7.17                                                                               a  3 3.33                                                                               a-b                 4     3 0.0  a  3 0.0  a  3 248.1                                                                              c-d                                                                               3 1.707                                                                              b-d                                                                               3 4.58                                                                               b  3 2.83                                                                               a-b                 8     3 0.0  a  3 0.0  a  3 289.4                                                                              a-c                                                                               3 1.530                                                                              c-d                                                                               3 0.92                                                                               c  3 3.17                                                                               a-b                 Example No. 113                                                                2     3 0.0  a  3 0.0  a  3 228.5                                                                              d  3 1.800                                                                              b-c                                                                               3 5.00                                                                               b  3 3.33                                                                               a-b                 4     3 0.0  a  3 0.0  a  3 260.6                                                                              b-d                                                                               3 1.747                                                                              b-c                                                                               3 0.00                                                                               c  3 2.17                                                                               b                   8     3 8.3  a  3 0.0  a  3 165.9                                                                              e  2 2.232                                                                              a  3 0.00                                                                               c  3 0.67                                                                               c                   A204 + Example No. 113                                                         2 + 2 3 0.0  a  3 0.0  a  3 285.7                                                                              a-c                                                                               3 1.557                                                                              c-d                                                                               3 0.25                                                                               c  3 2.92                                                                               a- b                2 + 4 3 0.0  a  3 0.0  a  3 281.1                                                                              b-d                                                                               3 1.634                                                                              b-d                                                                               3 0.00                                                                               c  3 0.75                                                                               c                   2 + 8 3 16.7 a  3 0.0  a  3 190.0                                                                              e  2 2.060                                                                              a-b                                                                               3 0.00                                                                               c  3 0.50                                                                               c                   4 + 2 3 8.3  a  3 0.0  a  3 270.2                                                                              b-d                                                                               2 1.604                                                                              b-d                                                                               3 0.00                                                                               c  3 2.08                                                                               b                   4 + 4 3 0.0  a  3 0.0  a  3 258.9                                                                              b-d                                                                               3 1.669                                                                              b-d                                                                               3 0.00                                                                               c  3 0.75                                                                               c                   4 + 8 3 16.7 a  3 0.0  a  3 185.4                                                                              e  2 2.164                                                                              a  3 0.00                                                                               c  3 0.00                                                                               c                   8 + 2 3 8.3  a  3 0.0  a  3 306.2                                                                              a-b                                                                               2 1.546                                                                              c-d                                                                               3 0.00                                                                               c  3 0.67                                                                               c                   8 + 4 3 0.0  a  3 0.0  a  3 272.4                                                                              b-d                                                                               3 1.672                                                                              b-d                                                                               3 0.00                                                                               c  3 0.33                                                                               c                   8 + 8 3 16.7 a  3 0.0  a  3 177.0                                                                              e  1 2.424                                                                              a  3 0.00                                                                               c  3 0.00                                                                               c                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 53                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina, E. maxima and E. tenella                                                                                    Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    4 0.0  a  4 0.0  a  4 325.9                                                                              a  4 1.423                                                                              c-d                                                                               4 0.00                                                                               c  4 0.00                                                                               f                   IC                                                                              0    4 0.0  a  4 0.0  a  4 254.8                                                                              c-e                                                                               4 1.666                                                                              a-c                                                                               4 8.81                                                                               a  4 3.31                                                                               c                   A80190                                                                         30    4 0.0  a  4 0.0  a  4 313.5                                                                              a-b                                                                               4 1.428                                                                              c-d                                                                               4 0.00                                                                               c  4 0.44                                                                               e                   40    4 0.0  a  4 0.0  a  4 317.3                                                                              a  4 1.392                                                                              d  4 0.00                                                                               c  4 0.00                                                                               f                   50    4 0.0  a  4 0.0  a  4 309.2                                                                              a-b                                                                               4 1.462                                                                              c-d                                                                               4 0.00                                                                               c  4 0.00                                                                               f                   Example No. 57                                                                  2    4 0.0  a  4 0.0  a  4 221.9                                                                              e  4 1.809                                                                              a  4 8.50                                                                               b  4 3.56                                                                               b                    3    4 0.0  a  4 0.0  a  4 232.4                                                                              d-e                                                                               4 1.730                                                                              a-b                                                                               4 8.69                                                                               a-b                                                                               4 3.06                                                                               d                    4    4 0.0  a  4 0.0  a  4 222.9                                                                              e  4 1.880                                                                              a  4 8.88                                                                               a  4 3.81                                                                               a                   A80190 + Example No. 57                                                        30 + 2                                                                               4 6.3  a  4 0.0  a  4 307.5                                                                              a-b                                                                               4 1.520                                                                              b-d                                                                               4 0.00                                                                               c  4 0.00                                                                               f                   30 + 3                                                                               4 0.0  a  4 0.0  a  4 292.4                                                                              a-c                                                                               4 1.533                                                                              b-d                                                                               4 0.00                                                                               c  4 0.00                                                                               f                   30 + 4                                                                               4 0.0  a  4 0.0  a  4 306.8                                                                              a-b                                                                               4 1.472                                                                              c-d                                                                               4 0.00                                                                               c  4 0.00                                                                               f                   40 + 2                                                                               4 0.0  a  4 0.0  a  4 285.4                                                                              a-c                                                                               4 1.468                                                                              c-d                                                                               4 0.00                                                                               c  4 0.00                                                                               f                   40 + 3                                                                               4 0.0  a  4 0.0  a  4 298.0                                                                              a-c                                                                               4 1.498                                                                              b-d                                                                               4 0.00                                                                               c  4 0.00                                                                               f                   40 + 4                                                                               4 0.0  a  4 0.0  a  4 287.3                                                                              a-c                                                                               4 1.538                                                                              b-d                                                                               4 0.00                                                                               c  4 0.00                                                                               f                   50 + 2                                                                               4 6.3  a  4 0.0  a  4 299.4                                                                              a-c                                                                               4 1.524                                                                              b-d                                                                               4 0.00                                                                               c  4 0.00                                                                               f                   50 + 3                                                                               4 0.0  a  4 0.0  a  4 255.1                                                                              c-e                                                                               4 1.781                                                                              a  4 0.00                                                                               c  4 0.00                                                                               f                   50 + 4                                                                               4 0.0  a  4 0.0  a  4 267.0                                                                              b-d                                                                               4 1.672                                                                              a-c                                                                               4 0.00                                                                               c  4 0.00                                                                               f                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 54                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina, E. maxima and E. tenella                                                                                    Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    4 0.0  a  4 0.0  a  4 322.3                                                                              a  4 1.356                                                                              e  4 0.00                                                                               e  4 0.38                                                                               d                   IC                                                                              0    4 18.8 a  4 18.8 a  4 203.6                                                                              c  4 1.865                                                                              b-d                                                                               4 8.44                                                                               a  4 3.44                                                                               a                   A80190                                                                         30    4 6.3  a  4 0.0  a  4 259.4                                                                              b  4 1.624                                                                              c-e                                                                               4 6.90                                                                               a-b                                                                               4 3.54                                                                               a                   40    4 0.0  a  4 0.0  a  4 229.6                                                                              b-c                                                                               4 1.670                                                                              b-e                                                                               4 5.13                                                                               b-c                                                                               4 2.81                                                                               a-b                 50    4 0.0  a  4 0.0  a  4 285.5                                                                              a-b                                                                               4 1.449                                                                              e  4 1.94                                                                               d-e                                                                               4 2.00                                                                               b-c                 Example No. 57                                                                  2    4 6.3  a  4 6.3  a  4 186.4                                                                              c-d                                                                               4 1.955                                                                              b  4 8.81                                                                               a  4 3.56                                                                               a                    3    4 12.5 a  4 12.5 a  4 203.0                                                                              c  4 1.885                                                                              b-c                                                                               4 8.31                                                                               a  4 3.75                                                                               a                    4    4 6.3  a  4 6.3  a  4 151.9                                                                              d  4 2.285                                                                              a  4 8.81                                                                               a  4 3.88                                                                               a                   A80190 + Example No. 57                                                        30 + 2                                                                               4 0.0  a  4 0.0  a  4 260.5                                                                              b  4 1.589                                                                              c-e                                                                               4 3.75                                                                               c-d                                                                               4 3.56                                                                               a                   30 + 3                                                                               4 6.3  a  4 0.0  a  4 270.8                                                                              a-b                                                                               4 1.490                                                                              d-e                                                                               4 3.08                                                                               c-e                                                                               4 3.19                                                                               a-b                 30 + 4                                                                               4 0.0  a  4 0.0  a  4 274.6                                                                              a-b                                                                               4 1.495                                                                              d-e                                                                               4 0.81                                                                               e  4 2.00                                                                               b-c                 40 + 2                                                                               4 6.3  a  4 6.3  a  4 256.9                                                                              b  4 1.549                                                                              c-e                                                                               4 3.81                                                                               c-d                                                                               4 2.75                                                                               a-b                 40 + 3                                                                               4 0.0  a  4 0.0  a  4 290.2                                                                              a-b                                                                               4 1.486                                                                              d-e                                                                               4 0.94                                                                               e  4 1.50                                                                               c-d                 40 + 4                                                                               4 0.0  a  4 0.0  a  4 276.8                                                                              a-b                                                                               4 1.554                                                                              c-e                                                                               4 0.31                                                                               e  4 1.44                                                                               c-d                 50 + 2                                                                               4 0.0  a  4 0.0  a  4 287.8                                                                              a-b                                                                               4 1.486                                                                              d-e                                                                               4 0.13                                                                               e  4 1.31                                                                               c-d                 50 + 3                                                                               4 0.0  a  4 0.0  a  4 271.2                                                                              a-b                                                                               4 1.615                                                                              c-e                                                                               4 0.13                                                                               e  4 0.88                                                                               c-d                 50 + 4                                                                               4 0.0  a  4 0.0  a  4 263.4                                                                              b  4 1.566                                                                              c-e                                                                               4 0.50                                                                               e  4 0.63                                                                               d                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 55                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella, E. acervulina and E. maxima                                                                                    Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    3 0.0  b  3 0.0  b  3 218.8                                                                              a  3 1.285                                                                              d  3 0.00                                                                               b  3 0.00                                                                               d                   IC                                                                              0    3 40.0 a-b                                                                               3 40.0 a  3 105.2                                                                              c           3 1.50                                                                               a  3 3.44                                                                               a                   Example No. 22                                                                 15    3 86.7 a  3 0.0  b  1 5.9 e           1 0.00                                                                               b  1 0.00                                                                               d                   10    3 53.3 a-b                                                                               3 0.0  b  2 84.4                                                                               c-d                                                                               1 2.352                                                                              a  2 0.00                                                                               b  2 0.00                                                                               d                    5    3 13.3 b  3 0.0  b  3 144.6                                                                              b  1 1.675                                                                              b-c                                                                               3 0.08                                                                               b  3 2.05                                                                               b                   Example No. 15                                                                 15    3 6.7  b  3 0.0  b  3 146.4                                                                              b  2 1.811                                                                              b  3 0.00                                                                               b  3 1.77                                                                               b-c                 10    3 0.0  b  3 0.0  b  3 160.1                                                                              b  3 1.588                                                                              c  3 0.00                                                                               b  3 3.27                                                                               a                    5    3 26.7 b  3 26.7 a-b                                                                               3 132.3                                                                              b  1 1.747                                                                              b  3 0.00                                                                               b  3 3.60                                                                               a                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 56                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                               Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                              0    3 8.3  b  3 0.0  a  3 323.0                                                                              a  2 1.396                                                                              d  3 0.00                                                                               c  3 0.22                                                                               c                   IC                                                                              0    3 16.7 b  3 16.7 a  3 195.7                                                                              e  2 2.032                                                                              a  3 7.67                                                                               a  3 3.75                                                                               a                   A82810                                                                          1    3 8.3  b  3 8.3  a  3 202.0                                                                              e  2 2.032                                                                              b  3 7.42                                                                               a  3 3.50                                                                               a                    3    3 0.0  b  3 0.0  a  3 278.3                                                                              a-d                                                                               3 1.565                                                                              b-d                                                                               3 2.33                                                                               b  3 3.00                                                                               a                    5    3 0.0  b  3 0.0  a  3 317.3                                                                              a  3 1.448                                                                              c-d                                                                               3 0.50                                                                               c  3 1.50                                                                               b                   Example No. 36                                                                  6    3 33.3 a  3 25.0 a  3 211.6                                                                              e           3 7.08                                                                               a  3 3.69                                                                               a                   12    3 0.0  b  3 0.0  a  3 256.2                                                                              c-d                                                                               3 1.701                                                                              b  3 0.58                                                                               c  3 3.58                                                                               a                   24    3 0.0  b  3 0.0  a  3 232.1                                                                              d-e                                                                               3 1.832                                                                              a  3 0.00                                                                               c  3 1.42                                                                               b                   A82810 + Example No. 36                                                         1 + 6                                                                               3 0.0  b  3 0.0  a  3 268.7                                                                              b-d                                                                               3 1.533                                                                              b-d                                                                               3 0.17                                                                               c  3 2.92                                                                               a                    1 +  12                                                                             3 0.0  b  3 0.0  a  3 270.8                                                                              b-d                                                                               3 1.609                                                                              b-d                                                                               3 0.00                                                                               c  3 0.75                                                                               b-c                  1 + 24                                                                              3 0.0  b  3 0.0  a  3 212.1                                                                              e  3 1.902                                                                              a  3 0.00                                                                               c  3 1.08                                                                               b-c                  3 + 6                                                                               3 0.0  b  3 0.0  a  3 311.0                                                                              a-b                                                                               3 1.478                                                                              c-d                                                                               3 0.00                                                                               c  3 0.92                                                                               b-c                  3 + 12                                                                              3 0.0  b  3 0.0  a  3 278.8                                                                              a-d                                                                               3 1.581                                                                              b-d                                                                               3 0.00                                                                               c  3 0.17                                                                               c                    3 + 24                                                                              3 0.0  b  3 0.0  a  3 214.1                                                                              e  3 1.954                                                                              a  3 0.00                                                                               c  3 0.17                                                                               c                    5 + 6                                                                               3 0.0  b  3 0.0  a  3 290.9                                                                              a-c                                                                               3 1.501                                                                              c-d                                                                               3 0.00                                                                               c  3 0.17                                                                               c                    5 + 12                                                                              3 0.0  b  3 0.0  a  3 269.5                                                                              b-d                                                                               3 1.620                                                                              b-c                                                                               3 0.00                                                                               c  3 0.25                                                                               c                    5 + 24                                                                              3 8.3  b  3 0.0  a  3 205.8                                                                              e  2 1.974                                                                              a  3 0.00                                                                               c  3 0.19                                                                               c                   __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 57                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina, E. maxima and E. tenella                                                                         Lesion Scores                                 Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                            Intestinal                                                                           Cecal                                   PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean                                                                               # Mean                                                                               # Mean                                  __________________________________________________________________________     NC    4 0.0 d                                                                               4 0.0 a                                                                               4 224.4 a                                                                             4 1.655 f                                                                            4 0.00 b                                                                             4 0.00 f                                IC    4 15.0 d                                                                              4 5.0 a                                                                               4 117.2 d-f                                                                           1 2.602 c                                                                            4 6.43 a                                                                             4 3.17 a-b                              Example No. 94                                                                 20    4 95.0 a                                                                              4 0.0 a                                                                               1 108.4 d-f  1 0.00 b                                                                             1 0.00 f                                15    4 20.0 c-d                                                                            4 0.0 a                                                                               4 106.0 e-f                                                                           1 3.461 a                                                                            4 0.00 b                                                                             4 0.31 e-f                              12.5  4 0.0 d                                                                               4 0.0 a                                                                               4 127.4 d-f                                                                           4 2.543 c                                                                            4 0.00 b                                                                             4 0.25 e-f                              10    4 10.0 d                                                                              4 0.0 a                                                                               4 147.8 c-f                                                                           3 2.023 e                                                                            4 0.00 b                                                                             4 1.63 c-e                              5     4 5.0 d                                                                               4 5.0 a                                                                               4 199.2 a-b                                                                           3 1.917 e                                                                            4 0.00 b                                                                             4 2.16 c-d                              Example No. 98                                                                 20    4 90.0 a                                                                              4 0.0 a                                                                               2 14.9 g     2 0.00 b                                                                             2 1.00 d-f                              15    4 55.0 b                                                                              4 0.0 a                                                                               4 94.6 f     4 0.00 b                                                                             4 0.38 e-f                              12.5  4 35.0 c                                                                              4 0.0 a                                                                               4 101.9 e-f  4 0.00 b                                                                             4 0.90 d-f                              10    4 0.0 d                                                                               4 0.0 a                                                                               4 142.4 c-f                                                                           4 2.260 d                                                                            4 0.00 b                                                                             4 1.30 d-f                              5     4 0.0 d                                                                               4 0.0 a                                                                               4 183.1 b-c                                                                           4 1.854 e                                                                            4 0.00 b                                                                             4 2.35 b-c                              NC (Equal volume of ACETONE added)                                             0     2 0.0 d                                                                               2 0.0 a                                                                               2 235.5 a                                                                             2 1.521 f                                                                            2 0.00 b                                                                             2 0.00 f                                IC (Equal volume of ACETONE added)                                             0     2 10.0 d                                                                              2 10.0 a                                                                              2 101.1 e-f                                                                           1 2.931 b                                                                            2 6.25 a                                                                             2 3.80 a                                Example No. 94 (Dissolved in ACETONE)                                          20    2 100.0 a                                                                             2 0.0 a                                                           15    2 40.0 b-c                                                                            2 0.0 a                                                                               2 94.4 f     2 0.00 b                                                                             2 0.50 e-f                              10    2 0.0 d                                                                               2 0.0 a                                                                               2 166.5 b-e                                                                           2 2.003 e                                                                            2 0.00 b                                                                             2 1.30 d-f                              5     2 0.0 d                                                                               2 0.0 a                                                                               2 169.5 b-d                                                                           2 1.986 e                                                                            2 0.60 b                                                                             2 2.20 b-d                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 58                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina, and E. tenella                                                                                    Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                           Cecal                                  PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean                                                                               # Mean                                 __________________________________________________________________________     NC    3 0.0 a                                                                               3 0.0 a                                                                               3 332.8 a                                                                             3 1.448 c                                                                             3 0.00 b                                                                             3 0.00 e                               IC    3 0.0 a                                                                               3 0.0 a                                                                               3 256.0 b-c                                                                           3 1.691 a-c                                                                           3 7.42 a                                                                             3 2.92 a                               A204                                                                           2     3 8.3 a                                                                               3 0.0 a                                                                               3 263.9 b-c                                                                           2 1.744 a-b                                                                           3 8.00 a                                                                             3 3.25 a                               4     3 0.0 a                                                                               3 0.0 a                                                                               3 259.7 b-c                                                                           3 1.595 a-c                                                                           3 6.00 a                                                                             3 3.08 a                               8     3 8.3 a                                                                               3 0.0 a                                                                               3 271.8 b-c                                                                           2 1.537 a-c                                                                           3 1.69 b                                                                             3 2.78 a                               Example No. 108                                                                2     3 0.0 a                                                                               3 0.0 a                                                                               3 237.3 c                                                                             3 1.831 a                                                                             3 7.75 a                                                                             4 3.17 a                               4     3 8.3 a                                                                               3 0.0 a                                                                               3 237.1 c                                                                             2 1.840 a                                                                             3 1.81 b                                                                             3 3.03 a                               8     3 8.3 a                                                                               3 0.0 a                                                                               3 242.9 c                                                                             2 1.707 a-c                                                                           3 0.00 b                                                                             3 2.22 a-c                             A204 + Example No. 108                                                         2 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 271.4 b-c                                                                           3 1.579 a-c                                                                           3 0.92 b                                                                             3 3.08 a                               2 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 282.9 a-c                                                                           3 1.592 a-c                                                                           3 0.00 b                                                                             3 2.58 a-b                             2 + 8 3 0.0 a                                                                               4 0.0 a                                                                               3 264.3 b-c                                                                           3 1.644 a-c                                                                           3 0.00 b                                                                             3 1.17 c-e                             4 +  2                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 305.7 a-b                                                                           3 1.509 b-c                                                                           3 0.00 b                                                                             3 2.40 a-b                             4 + 4 3 8.3 a                                                                               3 0.0 a                                                                               3 271.3 b-c                                                                           2 1.637 a-c                                                                           3 0.00 b                                                                             3 1.44 b-d                             4 + 8 3 0.0 a                                                                               3 0.0 a                                                                               3 251.8 b-c                                                                           3 1.670 a-c                                                                           3 0.00 b                                                                             3 0.33 d-e                             8 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 290.0 a-c                                                                           3 1.448 c                                                                             3 0.00 b                                                                             3 1.83 a-c                             8 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 269.0 b-c                                                                           3 1.508 b-c                                                                           3 0.00 b                                                                             3 0.50 d-e                             8 + 8 3 8.3 a                                                                               3 0.0 a                                                                               3 251.2 b-c                                                                           2 1.708 a-c                                                                           3 0.00 b                                                                             3 0.00 e                               __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 59                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                     Lesion Scores                                Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    4 0.0 a                                                                               4 0.0 e                                                                               4 315.6 a                                                                             4 1.457 c-d                                                                           4 0.00 g                                                                              4 0.00 d                              IC    4 0.0 e                                                                               4 0.0 e                                                                               4 242.1 b-d                                                                           4 1.736 a-c                                                                           4 5.50 a-b                                                                            4 3.63 a                              MADURAMICIN                                                                    2     4 6.3 a-d                                                                             4 0.0 e                                                                               4 267.2 a-c                                                                           4 1.601 c-d                                                                           4 5.00 a-c                                                                            4 3.48 a                              3     4 0.0 e                                                                               4 0.0 e                                                                               4 265.0 a-c                                                                           4 1.639 b-c                                                                           4 4.06 b-d                                                                            4 3.50 a                              4     4 0.0 e                                                                               4 0.0 e                                                                               4 298.7 a                                                                             4 1.464 c-d                                                                           4 4.31 a-d                                                                            4 3.63 a                              5     4 0.0 e                                                                               4 0.0 e                                                                               4 291.7 a-b                                                                           4 1.544 c-d                                                                           4 4.19 a-d                                                                            4 3.56 a                              Example No. 57                                                                 2     4 6.3 a-d                                                                             4 6.3 b                                                                               4 209.0 d                                                                             4 1.893 a                                                                             4 6.19 a                                                                              4 3.81 a                              3     4 0.0 e                                                                               4 0.0 e                                                                               4 229.2 c-d                                                                           4 1.763 a-c                                                                           4 5.75 a-b                                                                            4 3.38 a                              4     4 12.5 a                                                                              4 12.5 a                                                                              4 217.1 d                                                                             4 1.848 a-b                                                                           4 6.00 a-b                                                                            4 3.63 a                              5     4 0.0 e                                                                               4 0.0 e                                                                               4 233.1 c-d                                                                           4 1.869 a-b                                                                           4 4.31 a-d                                                                            4 3.69 a                              MADURAMICIN + Example No. 57                                                   2 + 2 4 0.0 e                                                                               4 0.0 e                                                                               4 281.3 a-b                                                                           4 1.544 c-d                                                                           4 3.31 c-e                                                                            4 3,56 a                              2 + 3 4 0.0 e                                                                               4 0.0 e                                                                               4 290.3 a-b                                                                           4 1.483 c-d                                                                           4 2.50 d-f                                                                            4 3.81 a                              2 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 289.4 a-b                                                                           4 1.483 c-d                                                                           4 1.63 e-g                                                                            4 3.56 a                              2 + 5 4 6.3 a-d                                                                             4 0.0 e                                                                               4 282.5 a-b                                                                           4 1.567 c-d                                                                           4 0.77 f-g                                                                            4 2.48 a-b                            3 + 2 4 0.0 e                                                                               4 0.0 e                                                                               4 291.6 a-b                                                                           4 1.591 c-d                                                                           4 2.56 d-f                                                                            4 3.50 a                              3 + 3 4 0.0 e                                                                               4 0.0 e                                                                               4 283.2 a-b                                                                           4 1.495 c-d                                                                           4 1.75 e-g                                                                            4 3.50 a                              3 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 296.4 a                                                                             4 1.506 c-d                                                                           4 1.81 e-g                                                                            4 2.44 a-b                            3 + 5 4 0.0 e                                                                               4 0.0 e                                                                               4 278.4 a-b                                                                           4 1.544 c-d                                                                           4 1.38 e-g                                                                            4 2.19 b                              4 + 2 4 0.0 e                                                                               4 0.0 e                                                                               4 302.2 a                                                                             4 1.448 d                                                                             4 1.50 e-g                                                                            4 3.31 a                              4 + 3 3 0.0 e                                                                               4 0.0 e                                                                               4 289.5 a-b                                                                           4 1.538 c-d                                                                           4 2.13 e-g                                                                            4 3.50 a                              4 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 283.9 a-b                                                                           4 1.573 c-d                                                                           4 0.44 f-g                                                                            4 2.06 b                              4 + 5 4 0.0 e                                                                               4 0.0 e                                                                               4 295.0 a                                                                             4 1.509 c-d                                                                           4 0.69 f-g                                                                            4 1.44 b-c                            5 + 2 4 0.0 e                                                                               4 0.0 e                                                                               4 276.4 a-b                                                                           4 1.537 c-d                                                                           4 1.81 e-g                                                                            4 2.50 a-b                            5 + 3 4 0.0 e                                                                               4 0.0 e                                                                               4 299.0 a                                                                             4 1.476 c-d                                                                           4 0.94 f-g                                                                            4 2.50 a-b                            5 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 293.2 a-b                                                                           4 1.484 c-d                                                                           4 0.50 f-g                                                                            4 1.38 b-c                            5 + 5 4 0.0 e                                                                               4 0.0 e                                                                               4 287.4 a-b                                                                           4 1.575 c-d                                                                           4 0.19 g                                                                              4 1.00 c                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 60                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                         Lesion Scores                                Treatment                                                                            Mortality Mean (3)                                                                           Wt. Gain (4)                                                                          Feed/Gain (5)                                                                         Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC    4 0.0 e                                                                               4 0.0 e                                                                               4 325.8 a                                                                             4 1.453 f                                                                             4 0.00 j                                                                              4 0.00 h                              IC    4 25.0 a-c                                                                            4 18.8 b-c                                                                            4 154.5 g                                                                             4 2.431 a                                                                             4 8.42 a                                                                              4 3.83 a                              MADURAMICIN                                                                    2     4 12.5 b-e                                                                            4 12.5 b-e                                                                            4 187.8 f-f                                                                           4 2.155 b-c                                                                           4 8.06 a-b                                                                            4 3.69 a-b                            3     4 12.5 b-e                                                                            4 12.5 b-e                                                                            4 218.7 e-f                                                                           4 1.892 c-e                                                                           4 7.44 a-b                                                                            4 3.75 a-b                            4     4 0.0 e                                                                               4 0.0 e                                                                               4 223.2 e-f                                                                           4 1.799 d-f                                                                           4 7.38 a-b                                                                            4 3.63 a-c                            5     4 6.3 b-e                                                                             4 0.0 e                                                                               4 262.1 c-d                                                                           4 1.600 e-f                                                                           4 6.44 a-c                                                                            4 3.88 a                              Example No. 57                                                                 2     4 25.0 a-c                                                                            4 25.0 a-b                                                                            4 163.5 g                                                                             4 2.303 a-b                                                                           4 8.31 a-b                                                                            4 3.88 a                              3     4 37.5 a                                                                              4 37.5 a                                                                              4 159.4 g                                                                             4 2.496 a                                                                             4 8.44 a                                                                              4 3.94 a                              4     4 6.3 b-e                                                                             4 6.3 b-e                                                                             4 185.9 f-g                                                                           4 2.091 b-d                                                                           4 7.31 a-b                                                                            4 3.88 a                              5     4 6.3 b-e                                                                             4 6.3 b-e                                                                             4 203.8 f                                                                             4 2.007 c-d                                                                           4 7.88 a-b                                                                            4 3.50 a-c                            MADURAMICIN + Example No. 57                                                   2 + 2 4 12.5 b-e                                                                            4 12.5 b-e                                                                            4 248.7 d-e                                                                           4 1.787 d-f                                                                           4 6.63 a-c                                                                            4 4.00 a                              2 + 3 4 0.0 e                                                                               4 0.0 e                                                                               4 297.8 a-c                                                                           4 1.443 f                                                                             4 5.81 b-d                                                                            4 3.31 a-c                            2 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 295.5 a-d                                                                           4 1.502 f                                                                             4 4.81 c-e                                                                            4 3.63 a-c                            2 + 5 4 0.0 e                                                                               4 0.0 e                                                                               4 277.6 a-d                                                                           4 1.587 e-f                                                                           4 3.00 e-h                                                                            4 2.44 c-e                            3 + 2 4 0.0 e                                                                               4 0.0 e                                                                               4 273.4 b-d                                                                           4 1.653 e-f                                                                           4 6.38 a-c                                                                            4 3.56 a-c                            3 + 3 4 0.0 e                                                                               4 0.0 e                                                                               4 290.9 a-d                                                                           4 1.580 e-f                                                                           4 4.25 c-g                                                                            4 3.75 a-b                            3 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 302.0 a-c                                                                           4 1.484 f                                                                             4 3.69 d-g                                                                            4 2.50 b-e                            3 + 5 4 6.3 b-e                                                                             4 0.0 e                                                                               4 285.0 a-d                                                                           4 1.564 e-f                                                                           4 2.06 g-j                                                                            4 2.17 d-f                            4 +  2                                                                               4 0.0 e                                                                               4 0.0 e                                                                               4 291.4 a-d                                                                           4 1.514 f                                                                             4 4.44 c-g                                                                            4 3.63 a-c                            4 + 3 4 0.0 e                                                                               4 0.0 e                                                                               4 305.7 a-c                                                                           4 1.462 f                                                                             4 3.69 d-g                                                                            4 3.06 a-d                            4 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 301.6 a-c                                                                           4 1.471 f                                                                             4 2.25 f-j                                                                            4 1.75 e-f                            4 + 5 4 6.3 b-e                                                                             4 0.0 e                                                                               4 299.1 a-c                                                                           4 1.510 f                                                                             4 0.90 h-j                                                                            4 1.19 f-g                            5 + 2 4 6.3 b-e                                                                             4 0.0 e                                                                               4 313.7 a-c                                                                           4 1.463 f                                                                             4 4.60 c-f                                                                            4 2.52 b-e                            5 + 3 4 0.0 e                                                                               4 0.0 e                                                                               4 315.5 a-b                                                                           4 1.448 f                                                                             4 2.56 e-i                                                                            4 1.69 e-f                            5 + 4 4 0.0 e                                                                               4 0.0 e                                                                               4 302.4 a-c                                                                           4 1.461 f                                                                             4 1.00 h-j                                                                            4 1.19 f-g                            5 + 5 4 0.0 e                                                                               4 0.0 e                                                                               4 284.6 a-d                                                                           4 1.591 e-f                                                                           4 0.31 i-j                                                                            4 0.63 g-h                            __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 61                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                              Lesion Scores                                       Treatment                                                                            % Mort. (3)                                                                           Wt. Gain (4)                                                                          Feed/Gain (5)                                                                         Intestinal                                                                           Cecal                                         PPM   #  Mean                                                                               # Mean # Mean # Mean                                                                               # Mean                                        __________________________________________________________________________     NNC   3  0.0 a                                                                              3 280.7                                                                               2 1.452 b                                                                             3 0.00 d                                                                             3 0.00 e                                      IC    3  0.0 a                                                                              3 239.2 a-b                                                                           3 1.691 a-b                                                                           3 8.00 a                                                                             3 2.92 a-b                                    A204                                                                           2     3  8.3 1                                                                              3 261.3 a-b                                                                           2 1.662 a-b                                                                           3 6.75 a                                                                             3 3.08 a-b                                    4     3  0.0 a                                                                              4 235.1 a-b                                                                           3 1.621 a-b                                                                           3 5.00 b                                                                             3 3.42 a                                      8     3  0.0 a                                                                              4 253.1 a-b                                                                           2 1.456 b                                                                             3 1.00 d                                                                             3 2.00 a-d                                    Example No. 22                                                                 2     3  8.3 a                                                                              3 258.2 a-b                                                                           2 1.577 a-b                                                                           3 3.00 c                                                                             3 2.92 a-b                                    4     3  0.0 a                                                                              3 261.8 a-b                                                                           3 1.590 a-b                                                                           3 0.00 d                                                                             3 2.17 a-c                                    8     3  0.0 a                                                                              3 171.2 c                                                                             1 1.860 a-b                                                                           3 0.00 d                                                                             3 0.50 d-e                                    A204 + Example No. 22                                                          2 + 2 3  0.0 a                                                                              3 279.2 a                                                                             1 1.518 a-b                                                                           3 0.28 d                                                                             3 2.81 a-b                                    2 + 4 3  0.0 a                                                                              3 253.2 a-b                                                                           3 1.577 a-b                                                                           3 0.00 d                                                                             3 0.83 c-e                                    2 + 8 3  0.0 a                                                                              3 169.2 c                                                                             2 1.798 a-b                                                                           3 0.00 d                                                                             3 0.25 c                                      4 + 2 3  0.0 a                                                                              3 290.3 a                                                                             3 1.459 b                                                                             3 0.08 d                                                                             3 2.25 a-c                                    4 + 4 3  0.0 a                                                                              3 256.3 a-b                                                                           2 1.558 a-b                                                                           3 0.00 d                                                                             3 1.58 b-e                                    4 + 8 3  0.0 a                                                                              3 256.3 a-b   3 0.00 d                                                                             3 0.44 d-e                                    8 + 2 3  0.0 a                                                                              3 284.0 a                                                                             2 1.451 b                                                                             3 0.00 d                                                                             3 0.89 c-e                                    8 + 4 3  0.0 a                                                                              3 255.6 a-b                                                                           1 1.587 a-b                                                                           3 0.00 d                                                                             3 0.08 e                                      8 + 8 3  0.0 a                                                                              3 195.9 b-c                                                                           1 2.069 a                                                                             3 0.00 d                                                                             3 0.00 e                                      __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 62                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                              Lesion Scores                                       Treatment                                                                            % Mort. (3)                                                                           Wt. Gain (4)                                                                          Feed/Gain (5)                                                                         Intestinal                                                                           Cecal                                         PPM   #  Mean                                                                               # Mean # Mean # Mean                                                                               # Mean                                        __________________________________________________________________________     NNC   3  0.0 a                                                                              3 320.1 a                                                                             3 1.454 b                                                                             3 0.00 d                                                                             3 0.00 c                                      IC    3  0.0 a                                                                              3 277.3 c                                                                             3 1.787 a                                                                             3 8.80 a                                                                             3 3.42 a                                      A204                                                                           2     3  0.0 a                                                                              3 239.3 b-c                                                                           3 1.787 a                                                                             3 6.33 b                                                                             3 3.42 a                                      4     3  8.3 a                                                                              3 263.5 a-c                                                                           2 1.708 a-b                                                                           3 3.33 c                                                                             3 3.08 a                                      8     3  0.0 a                                                                              4 272.4 a-c                                                                           3 1.619 a-b                                                                           3 0.58 d                                                                             3 3.33 a                                       Example No. 57                                                                2     3  16.7 a                                                                             3 238.8 b-c                                                                           2 1.675 a-b                                                                           3 5.33 b                                                                             3 3.33 a                                      4     3  0.0 a                                                                              3 236.3 b-c                                                                           3 1.748 a                                                                             3 2.83 c-d                                                                           3 3.00 a                                      8     3  0.0 a                                                                              3 241.1 b-c                                                                           2 1.735 a-b                                                                           3 0.17 d                                                                             3 3.19 a                                      A204 + Example No. 57                                                          2 + 2 3  0.0 a                                                                              3 269.6 a-c                                                                           3 1.610 a-b                                                                           3 2.58 c-d                                                                           3 3.00 a                                      2 + 4 3  0.0 a                                                                              3 278.4 a-c                                                                           3 1.599 a-b                                                                           3 0.25 d                                                                             3 3.08 a                                      2 + 8 3  0.0 a                                                                              3 253.9 a-c                                                                           2 1.691 a-b                                                                           3 0.00 d                                                                             3 0.97 b-c                                    4 + 2 3  0.0 a                                                                              3 256.4 a-c                                                                           3 1.624 a-b                                                                           3 0.33 d                                                                             3 3.25 a                                      4 + 4 3  0.0 a                                                                              3 290.0 a-c                                                                           3 1.543 a-b                                                                           3 0.00 d                                                                             3 2.08 a-b                                    4 + 8 3  0.0 a                                                                              3 237.9 b-c                                                                           3 1.675 a-b                                                                           3 0.00 d                                                                             3 0.75 b-c                                    8 + 2 3  0.0 a                                                                              3 290.0 a-c                                                                           2 1.484 a-b                                                                           3 0.00 d                                                                             3 1.59 b-c                                    8 + 4 3  0.0 a                                                                              3 304.3 a-b                                                                           3 1.497 a-b                                                                           3 0.00 d                                                                             3 0.58 c                                      8 + 8 3  0.0 a                                                                              3 265.8 a-c                                                                           3 1.646 a-b                                                                           3 0.00 d                                                                             3 0.33 c                                      __________________________________________________________________________ 

I claim:
 1. A method of treating coccidiosis attributable to Eimeria in a fowl which comprises administering to the fowl an effective amount of an active agent selected from compounds of the formulae ##STR3## wherein R¹ represents bromo or chloro,m represents an integer of 0 or 1 and n represents an integer of from 0 to 3, with the sum of m and n being an integer of from 1 to 3; R² represents difluoroacetyl, chlorodifluoroacetyl, 2,2,3,3-tetrafluoropropionyl, or a perfluoroalkanoyl of from C₂ to C₄ ; R³ represents H, trichloroacetyl, or an independently selected R² as described above; R⁴ represents H, OH, OCH₃, or a group hydrolyzable to a foregoing R⁴ moiety; and R⁵ represents difluoromethyl, chlorodifluoromethyl, 1,1,2,2-tetrafluoroethyl, or a perfluoroalkyl of C₁ -C₃ ; or a physiologically acceptable salt of a Formula II compound.
 2. The method of claim 1 wherein the active agent is a compound of Formula I.
 3. The method of claim 2 wherein the active agent is 3-nitro-5-(trifluoromethyl)-N¹ -(2,2,3,3-tetrafluoropropionyl)-o-phenylenediamine.
 4. The method of claim 1 wherein the active agent is a compound of Formula II.
 5. The method of claim 4 wherein the active agent is 4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-tetrafluoroethyl)benzimidazole or a physiologically acceptable salt thereof.
 6. The method of claim 4 wherein the active agent is 1-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-tetrafluoroethyl)benzimidazole or a physiologically acceptable salt thereof.
 7. The method of claim 1 wherein the coccidiosis is attributable to a strain of Eimeria which is polyether insensitive.
 8. The method of claim 7 wherein the active agent is 1-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-tetrafluoroethyl)benzimidazole. 